Search Results - "TSAI, Peter"
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Differential Changes in Gut Microbiota After Gastric Bypass and Sleeve Gastrectomy Bariatric Surgery Vary According to Diabetes Remission
Published in Obesity surgery (01-04-2017)“…Background It is unclear whether specific gut microbiota is associated with remission of type 2 diabetes (T2D) after distinct types of bariatric surgery. Aims…”
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Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits
Published in Nature neuroscience (01-09-2020)“…Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-relevant…”
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Marine biogeographic realms and species endemicity
Published in Nature communications (20-10-2017)“…Marine biogeographic realms have been inferred from small groups of species in particular environments (e.g., coastal, pelagic), without a global map of realms…”
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Cerebellar Dysfunction in Autism Spectrum Disorders: Deriving Mechanistic Insights from an Internal Model Framework
Published in Neuroscience (10-05-2021)“…•Cerebellar generated internal models are disrupted in autism spectrum disorders.•Cerebellar-mediated prediction and adaptation is impaired in…”
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Adaptive Prediction for Social Contexts: The Cerebellar Contribution to Typical and Atypical Social Behaviors
Published in Annual review of neuroscience (08-07-2021)“…Social interactions involve processes ranging from face recognition to understanding others' intentions. To guide appropriate behavior in a given context,…”
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Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice
Published in Nature neuroscience (01-12-2017)“…Cerebellar abnormalities, particularly in Right Crus I (RCrusI), are consistently reported in autism spectrum disorders (ASD). Although RCrusI is functionally…”
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Hierarchical heterogeneity and an elastic microstructure observed in a metallic glass alloy
Published in Acta materialia (15-10-2017)“…Heterogeneities in a Zr-based bulk metallic glass (BMG) were investigated using dynamic modulus mapping on a nanoindentation platform, revealing a complex…”
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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
Published in Nature (London) (30-08-2012)“…Both heterozygous loss and homozygous loss of Tsc1 in mouse cerebellar Purkinje cells (PCs) result in autistic-like behaviours, which can be prevented by…”
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Autism and cerebellar dysfunction: Evidence from animal models
Published in Seminars in fetal & neonatal medicine (01-10-2016)“…Summary Autism is a prevalent neurodevelopmental disorder whose origins are not well understood. Cerebellar involvement has been implicated in the pathogenesis…”
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N95 Respirator Cleaning and Reuse Methods Proposed by the Inventor of the N95 Mask Material
Published in The Journal of emergency medicine (01-05-2020)Get full text
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Outcomes of Anatomic Lung Resection for Cancer Are Better When Performed by Cardiothoracic Surgeons
Published in The Annals of thoracic surgery (01-03-2021)“…Anatomic lung resection (ALR) outcomes are superior for cardiothoracic surgeons (CTSs) by analysis of Medicare; National Inpatient Sample; South Carolina…”
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Update on the Association of Inflammation and Atrial Fibrillation
Published in Journal of cardiovascular electrophysiology (01-09-2010)“…Update on the Association of Inflammation and Atrial Fibrillation. Atrial fibrillation (AF) is a common arrhythmia and is associated with significant morbidity…”
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Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors
Published in Cell reports (Cambridge) (09-10-2018)“…Despite a prevalence exceeding 1%, mechanisms underlying autism spectrum disorders (ASDs) are poorly understood, and targeted therapies and guiding parameters…”
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A Critical Period for Development of Cerebellar-Mediated Autism-Relevant Social Behavior
Published in The Journal of neuroscience (30-03-2022)“…The cerebellum has been increasingly implicated in autism spectrum disorder (ASD) with many ASD-linked genes impacting both cerebellar function and…”
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Therapeutic Targeting of mTORC2 in mTORopathies
Published in Neuron (Cambridge, Mass.) (18-12-2019)“…Dysregulated mTOR contributes to neurodevelopmental dysfunction. A new study (Chen et al., 2019) demonstrates that suppression of mTORC2, not mTORC1,…”
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Uropathogenic Escherichia coli Releases Extracellular Vesicles That Are Associated with RNA
Published in PloS one (08-08-2016)“…Bacterium-to-host signalling during infection is a complex process involving proteins, lipids and other diffusible signals that manipulate host cell biology…”
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Assessing the complex sponge microbiota: core, variable and species-specific bacterial communities in marine sponges
Published in The ISME Journal (01-03-2012)“…Marine sponges are well known for their associations with highly diverse, yet very specific and often highly similar microbiota. The aim of this study was to…”
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Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models
Published in Cell reports (Cambridge) (26-12-2023)“…Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although cerebellar pathology has been observed in individuals with fragile X…”
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Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy
Published in Cell reports (Cambridge) (25-07-2017)“…Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder characterized by mutations in either the TSC1 or TSC2 genes, whose products form a critical…”
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