Search Results - "TRYPHONAS, L"

Skin reservoir formation and bioavailability of dermally administered chemicals in hairless guinea pigs by Chu, I., Dick, D., Bronaugh, R., Tryphonas, L.

“…There is concern as to whether dermally applied chemicals that remain in the skin after exposure are: bioavailable and should be included as part of the…”
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A 60 Hz magnetic field does not affect the incidence of squamous cell carcinomas in SENCAR mice by McLean, J.R., Thansandote, A., McNamee, J.P., Tryphonas, L., Lecuyer, D., Gajda, G.

“…Two groups of SENCAR mice were treated with a single dose of carcinogen and then, for 23 weeks, with a chemical tumor promoter to induce skin tumors. During…”
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Domoic acid poisoning and mussel-associated intoxication: preliminary investigations into the response of mice and rats to toxic mussel extract by Iverson, F, Truelove, J, Nera, E, Tryphonas, L, Campbell, J, Lok, E

“…Consumption of cultivated blue mussels from Prince Edward Island was recently associated with episodes of gastro-intestinal and neurological distress. Extracts…”
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Histomorphogenesis of soman-induced encephalocardiomyopathy in Sprague-Dawley rats by Tryphonas, L, Clement, J G

“…Although myocardial damage caused by soman has been previously reported, its relation to brain damage is unclear. In order to clarify this relationship, we…”
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Acute neurotoxicity of domoic acid in the rat by Tryphonas, L, Truelove, J, Nera, E, Iverson, F

“…A recent outbreak of human food poisoning, characterized by severe gastrointestinal and neurologic abnormalities, with a fatal outcome in 3 patients, was…”
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Experimental oral toxicity of domoic acid in cynomolgus monkeys (Macaca fascicularis) and rats. Preliminary investigations by Tryphonas, L, Truelove, J, Todd, E, Nera, E, Iverson, F

“…A recent outbreak of marine food poisoning in humans was attributed to the consumption of blue mussels (Mytilus edulis L.) contaminated with domoic acid (DA)…”
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Neuropathology of excitatory neurotoxins: the domoic acid model by Tryphonas, L, Iverson, F

“…A novel type of intoxication in Canada in 1987 was traced to consumption of cultivated mussels contaminated with the excitotoxin domoic acid. Studies carried…”
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A 60-Hz magnetic field increases the incidence of squamous cell carcinomas in mice previously exposed to chemical carcinogens by McLean, J., Thansandote, A., Lecuyer, D., Goddard, M., Tryphonas, L., Scaiano, J.C., Johnson, F.

“…The exposure of tumor-bearing SENCAR mice to a magnetic field of 2 mT at a frequency of 60 Hz for 52 weeks, was found to increase the rate of malignant…”
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Effects of the spermicide nonoxynol-9 on the pregnant uterus and the conceptus of rat by Tryphonas, L, Buttar, H S

“…In a series of experiments the embryotoxic potential of nonoxynol-9 (N-9) was investigated in adult female rats given a single per vaginam application of 5…”
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A Case of Traumatic Reticulitis (Intraparietal Fistula) by Tryphonas, L

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Nerve cell degeneration and progeny survival following ethylenethiourea treatment during pregnancy in rats by Khera, K S, Tryphonas, L

“…Ethylenethiourea (ETU)-induced early histologic changes in fetal CNS and their effect on postnatal survival was studied at 0, 15 or 30 mg/kg administered as…”
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Alteration of neuronal cytoskeletal organization in dorsal root ganglia associated with pyridoxine neurotoxicity by MONTPETIT, V. J. A, CLAPIN, D. F, TRYPHONAS, L, DANCEA, S

“…The pathogenesis of the sensory neurotoxicity arising from high doses of pyridoxine is obscure. Beagle dogs were fed 200 mg pyridoxine/kg per day and killed at…”
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Ethylenethiourea-induced hydrocephalus: pre- and postnatal pathogenesis in offspring from rats given a single oral dose during pregnancy by Khera, K S, Tryphonas, L

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A pilot study in adult rhesus monkeys (M. mulatta) treated with Aroclor 1254 for two years by Tryphonas, L, Arnold, D L, Zawidzka, Z, Mes, J, Charbonneau, S, Wong, J

“…Aroclor 1254, at a dose level of 280 micrograms/kg body weight equivalent to 200 micrograms/kg/day, was given 5 days per week to rhesus monkeys over a 27 to 28…”
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Morphologic evidence for vaginal toxicity of Delfen contraceptive cream in the rat by Tryphonas, L, Buttar, H S

“…The morphologic effects of Delfen contraceptive cream on the female genital tract were evaluated in young female rats given a single per vaginum application…”
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Polychlorinated biphenyl toxicity in the pregnant cynomolgus monkey: a pilot study by Truelove, J, Grant, D, Mes, J, Tryphonas, H, Tryphonas, L, Zawidzka, Z

“…Three pregnant cynomolgus monkeys were dosed with 100 or 400 mg/kg/day of Aroclor 1254 from approximately 60 days of gestation. The two monkeys given the lower…”
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Reversal by testosterone of atrophy of accessory genital glands of castrated male sheep. A histologic and morphometric study by Tryphonas, L, Hidiroglou, M, Collins, B

“…The histologic features of male accessory genital glands of entire sheep (group I), castrated sheep (group II), castrated sheep treated with 40 daily…”
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Isoniazid-induced hepatic steatosis in rabbits: an explanation for susceptibility and its antagonism by pyridoxine hydrochloride by Whitehouse, L W, Tryphonas, L, Paul, C J, Solomonraj, G, Thomas, B H, Wong, L T

“…Steatosis was induced in rabbits by subacute administration of isoniazid (INH, 50 mg/kg po). Concomitant treatment with pyridoxine (vitamin B6, 25 mg/kg po)…”
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Lead poisoning in cattle: brain lesions and hematologic changes by Christian, R G, Tryphonas, L

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Nuclear jaundice (kernicterus) in a newborn kitten by Tryphonas, L, Rozdilsky, B

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