Search Results - "TRONKO, Mykola D"
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ETV6‐NTRK3 is a common chromosomal rearrangement in radiation‐associated thyroid cancer
Published in Cancer (15-03-2014)“…BACKGROUND In their previous analysis of papillary thyroid carcinomas (PTCs) from an Ukrainian‐American cohort that was exposed to iodine‐131 (131I) from the…”
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Histopathological analysis of papillary thyroid carcinoma detected during ultrasound screening examinations in Fukushima
Published in Cancer science (01-02-2019)“…Thyroid ultrasound screening of young residents in Fukushima Prefecture, Japan, showed a high detection rate of papillary thyroid carcinoma (PTC). Detailed…”
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Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer
Published in JNCI : Journal of the National Cancer Institute (01-04-2018)“…Exposure to ionizing radiation during childhood is a well-established risk factor for thyroid cancer. However, the genetic mechanisms of radiation-associated…”
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Papillary Thyroid Carcinoma in Ukraine After Chernobyl and in Japan After Fukushima: Different Histopathological Scenarios
Published in Thyroid (New York, N.Y.) (01-09-2021)“…A significant increase in the incidence of papillary thyroid carcinoma (PTC) in subjects exposed to radiation at a young age is a well-documented health…”
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Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident
Published in Nature communications (13-06-2024)“…Childhood radioactive iodine exposure from the Chornobyl accident increased papillary thyroid carcinoma (PTC) risk. While cervical lymph node metastases (cLNM)…”
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Comparative Histopathologic Analysis of "Radiogenic" and "Sporadic" Papillary Thyroid Carcinoma: Patients Born Before and After the Chernobyl Accident
Published in Thyroid (New York, N.Y.) (01-07-2018)“…The issue of whether radiation-induced thyroid cancer is pathologically different from sporadic remains not fully answered. This study compared structural…”
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Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort
Published in British journal of cancer (01-12-2015)“…Background: There are limited data on the histopathology of papillary thyroid carcinomas (PTCs) diagnosed in irradiated populations. We evaluated the…”
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Comparative histopathological analysis of sporadic pediatric papillary thyroid carcinoma from Japan and Ukraine
Published in ENDOCRINE JOURNAL (01-01-2017)“…This study set out to compare structural and invasive characteristics of sporadic papillary thyroid carcinoma (PTC) in age-matched groups of children and…”
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Impact of uncertainties in exposure assessment on estimates of thyroid cancer risk among Ukrainian children and adolescents exposed from the Chernobyl accident
Published in PloS one (29-01-2014)“…The 1986 accident at the Chernobyl nuclear power plant remains the most serious nuclear accident in history, and excess thyroid cancers, particularly among…”
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A Cohort Study of Thyroid Cancer and Other Thyroid Diseases After the Chornobyl Accident: Thyroid Cancer in Ukraine Detected During First Screening
Published in JNCI : Journal of the National Cancer Institute (05-07-2006)“…Background: The Chornobyl accident in 1986 exposed thousands of people to radioactive iodine isotopes, particularly 131I; this exposure was followed by a large…”
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Iodine-131 dose dependent gene expression in thyroid cancers and corresponding normal tissues following the Chernobyl accident
Published in PloS one (25-07-2012)“…The strong and consistent relationship between irradiation at a young age and subsequent thyroid cancer provides an excellent model for studying radiation…”
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Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
Published in Cancer letters (01-06-2004)“…Point mutations of the BRAF gene have been recently described with high prevalence in papillary thyroid carcinomas. However, this molecular alteration has not…”
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1194-P: NT-proBNP, Subclinical Diastolic Dysfunction in Patients with DM Type 1 Treated with iSGLT2
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Aim: Subclinical diastolic dysfuntion in patients with preclinical heart failure with preserved ejection fraction (HFpEF) has been demonstrated in patients…”
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RET/PTC and PAX8/PPARγ chromosomal rearrangements in post‐Chernobyl thyroid cancer and their association with iodine‐131 radiation dose and other characteristics
Published in Cancer (15-05-2013)“…BACKGROUND: Childhood exposure to iodine‐131 from the 1986 nuclear accident in Chernobyl, Ukraine, led to a sharp increase in papillary thyroid carcinoma (PTC)…”
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I-131 Dose Response for Incident Thyroid Cancers in Ukraine Related to the Chornobyl Accident
Published in Environmental health perspectives (01-07-2011)“…Background: Current knowledge about Chornobyl-related thyroid cancer risks comes from ecological studies based on grouped doses, case-control studies, and…”
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RET/PTC and PAX8/PPAR[gamma] chromosomal rearrangements in post-Chernobyl thyroid cancer and their association with iodine-131 radiation dose and other characteristics
Published in Cancer (15-05-2013)“…BACKGROUND: Childhood exposure to iodine-131 from the 1986 nuclear accident in Chernobyl, Ukraine, led to a sharp increase in papillary thyroid carcinoma (PTC)…”
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2337-PUB: Impact of Treatment with Insulin and Other Hypoglycemic Drugs on 5'-AMP-Activated Protein Kinase Activity in Leukocytes of Patients with Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Background: The leukocytes play an essential role in the development of pathological conditions such as diabetes and its complications. The 5'-adenosine…”
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Utility of gene expression studies in relation to radiation exposure and clinical outcomes: thyroid cancer in the Ukrainian-American cohort and late health effects in a MAYAK worker cohort
Published in International journal of radiation biology (02-01-2021)“…We herein report on changes in gene expression after radiation exposure to iodine-131 from the Chernobyl accident in the Ukrainian-American thyroid cohort and…”
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487-P: The Activation of mTORC1 in Leukocytes of Patients with Cancer and Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Aim: mTOR/p70S6K1 play an important role in the pathogenesis of cancer and diabetes. Macrophages and lymphocytes are involved in the pathogenesis of diabetes,…”
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