Search Results - "TROCHIMOWICZ, HENRY J."

Cardiac sensitization: methodology and interpretation in risk assessment by Brock, William J., Rusch, George M., Trochimowicz, Henry J.

“…An increased sensitivity of the heart to endogenous epinephrine (adrenaline), a phenomenon referred to as cardiac sensitization, has long been recognized as a…”
Get full text

Inhalation toxicity and genotoxicity of hydrochlorofluorocarbon (HCFC)-225ca and HCFC-225cb by Brock, William J., Shin-Ya, Seiji, Rusch, George M., Hardy, Colin J., Trochimowicz, Henry J.

“…The acute, subchronic and genetic toxicity of the hydrochlorofluorocarbons HCFC‐225ca and HCFC‐225cb were evaluated to assist in establishing proper handling…”
Get full text

Acute, Subchronic, and Developmental Toxicity and Genotoxicity of 1,1,1-Trifluoroethane (HFC-143a) by BROCK, WILLIAM J., TROCHIMOWICZ, HENRY J., FARR, CRAIG H., MILLISCHER, RENE-JEAN, RUSCH, GEORGE M.

“…The toxicity potential of 1,1,1-trifluoroethane (HFC-143a), a CFC alternative, was evaluated in several acute, subchronic, and developmental toxicity studies…”
Get full text

Industrial research on alternative fluorocarbons by Trochimowicz, H J

“…Fluorocarbons containing chlorine or bromine have been associated with stratospheric ozone depletion and the search for suitable alternatives is progressing at…”
Get more information

Four-week repeated inhalation study of HCFC 225ca and HCFC 225cb in the common marmoset by Kurata, Yoshimasa, Takechi, Masato, Toyota, Naoto, Tsuchitani, Minoru, Katoh, Masanobu, Rusch, George M., Trochimowicz, Henry J., Shin-Ya, Seiji

“…Four male and three female marmosets in each group were exposed to air only, 1000 ppm of HCFC 225ca or 5000 ppm of HCFC 225cb, for 6 h per day for 28…”
Get full text

Subchronic Toxicity and Teratogenicity of 2-Chloro-1,1,1,2-tetrafluoroethane (HCFC-124) by MALLEY, LINDA A., CARAKOSTAS, MICHAEL, ELLIOTT, GLENN S., ALVAREZ, LOUIS, SCHROEDER, RAYMOND E., FRAME, STEVEN R., VAN PELT, CAROLYN, TROCHIMOWICZ, HENRY J., RUSCH, G. M.

“…Inhalation studies were conducted to determine the potential toxicity of HCFC–124. Groups of rats and mice were exposed to HCFC-124 6 hr/day, 5 days/week for…”
Get full text

Induction of nasal tumors in rats exposed to hexamethylphosphoramide by inhalation by Lee, K P, Trochimowicz, H J

“…Charles River-CD Sprague-Dawley rats in 4 equal groups of 240 each were exposed to 4,000, 400, 50, and 0 ppb of hexamethylphosphoramide (HMPA) vapor for 9 to…”
Get more information

Chronic Toxicity, Oncogenicity, and Mutagenicity Studies with Chlorotetrafluoroethane (HCFC-124) by Malley, Linda A., Frame, Steven R., Elliott, Glenn S., Bentley, Karin S., Brock, William J., Trochimowicz, Henry J., Rusch, George M.

“…ABSTRACT The chronic toxicity, oncogenicity, and mutagenicity of chlorotetrafluoroethane (HCFC-124) were evaluated. in the chronic toxicity/oncogenicity study,…”
Get full text

Teratogenic evaluation of 1,4-dichlorobutene-2 in the rat following inhalation exposure by Kennedy, Jr, G L, Culik, R, Trochimowicz, H J

Get more information

Toxicological evaluation of 1,1,1,2,2-pentafluoroethane (HFC-125) by Kawano, T, Trochimowicz, H J, Malinverno, G, Rusch, G M

“…Acute, subacute, and subchronic inhalation toxicity studies, developmental toxicity studies, a cardiac sensitization evaluation, and mutagenicity assays were…”
Get more information

Two-year inhalation toxicity study in rats with hydrochlorofluorocarbon 123 by Malley, L A, Carakostas, M, Hansen, J F, Rusch, G M, Kelly, D P, Trochimowicz, H J

“…The potential chronic toxicity and oncogenicity of hydrochlorofluorocarbon 123 (HCFC-123) was evaluated by exposing male and female rats to 0, 300, 1000, or…”
Get more information

Acute, Subchronic, and Developmental Toxicity and Genotoxicity of 1,1,1-Trifluoroethane (HFC-143a) by Brock, William J., Trochimowicz, Henry J., Farr, Craig H., Millischer, Rene-Jean, Rusch, George M.

“…The toxicity potential of 1,1,1-trifluoroethane (HFC-143a), a CFC alternative, was evaluated in several acute, subchronic, and developmental toxicity studies…”
Get full text

Subchronic inhalation toxicity studies with hydrochlorofluorocarbon 123 (HCFC 123) by Rusch, G M, Trochimowicz, H J, Malley, L J, Kelly, D P, Peckham, J, Hansen, J, Charm, J B

“…Hydrochlorofluorocarbon 123 (HCFC 123) is one of the chemicals being considered as a replacement for the chlorofluorocarbons. Four subchronic inhalation…”
Get more information

Subchronic Toxicity and Teratogenicity of 2-Chloro-1,1,1,2-tetrafluoroethane (HCFC-124) by Malley, Linda A., Carakostas, Michael, Elliott, Glenn S., Alvarez, Louis, Schroeder, Raymond E., Frame, Steven R., Pelt, Carolyn Van, Trochimowicz, Henry J., Rusch, G.M.

“…Inhalation studies were conducted to determine the potential toxicity of HCFC-124. Groups of rats and mice were exposed to HCFC-124 6 hr/day, 5 days/week for…”
Get full text

The effect of myocardial infarction on the cardiac sensitization potential of certain halocarbons by Trochimowicz, H J, Reinhardt, C F, Mullin, L S, Azar, A, Karrh, B W

“…We have previously shown that many halocarbons and hydrocarbons are capable of producing cardiac sensitization. Briefly, the test method involved exposure of…”
Get more information