Search Results - "TRIP, M. D"

Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP) : a prospective, randomised, double-blind trial by SMILDE, T. J, VAN WISSEN, S, WOLLERSHEIM, H, TRIP, M. D, KASTELEIN, J. J. P, STALENHOEF, A. F. H

“…High LDL-cholesterol is a risk factor for atherosclerosis. We aimed to determine whether aggressive cholesterol lowering with statins was more effective than…”
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The contribution of classical risk factors to cardiovascular disease in familial hypercholesterolaemia: data in 2400 patients by Jansen, A. C. M., Aalst‐Cohen, E. S., Tanck, M. W., Trip, M. D., Lansberg, P. J., Liem, A. H., Roeters van Lennep, H. W. O., Sijbrands, E. J. G., Kastelein, J. J. P.

“… Objective.  To determine the contribution of classical risk factors to the development of cardiovascular disease (CVD) in patients with heterozygous familial…”
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A Systematic Review and Meta-Analysis of Statin Therapy in Children With Familial Hypercholesterolemia by Avis, H J, Vissers, M N, Stein, E A, Wijburg, F A, Trip, M D, Kastelein, J J.P, Hutten, B A

“…OBJECTIVE—Functional and morphological changes of the arterial wall already present in young children with heterozygous familial hypercholesterolemia (HeFH)…”
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Colesevelam added to combination therapy with a statin and ezetimibe in patients with familial hypercholesterolemia: A 12-week, multicenter, randomized, double-blind, controlled trial by Huijgen, Roeland, MD, Abbink, Evertine J., MD, PhD, Bruckert, Eric, MD, Stalenhoef, Anton F.H., MD, PhD, FRCP, Imholz, Ben P.M., MD, PhD, Durrington, Paul N., MD, FMedSci, Trip, M.D., MD, PhD, Eriksson, Mats, MD, PhD, Visseren, Frank L.J., MD, PhD, Schaefer, Juergen R., MD, Kastelein, John J.P., MD, PhD

“…Abstract Background: Familial hypercholesterolemia (FH) has been associated with increased cardiovascular risk when untreated or when normal LDL-C…”
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Long-term LDL-c lowering in heterozygous familial hypercholesterolemia normalizes carotid intima-media thickness by Sivapalaratnam, S, van Loendersloot, L.L, Hutten, B.A, Kastelein, J.J.P, Trip, M.D, de Groot, E

“…Abstract Objective We investigated the effectiveness of statins in daily practice in reducing the arterial wall thicknesses by comparing the carotid…”
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Long term statin treatment reduces lipoprotein(a) concentrations in heterozygous familial hypercholesterolaemia by van Wissen, S, Smilde, T J, Trip, M D, de Boo, Th, Kastelein, J J P, Stalenhoef, A F H

“…Background: Raised plasma lipoprotein(a) (Lp(a)) is associated with increased risk of cardiovascular disease. It is unknown whether increased Lp(a) is an…”
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Abnormalities in liver function and coagulation profile following the Fontan procedure by van Nieuwenhuizen, R C, Peters, M, Lubbers, L J, Trip, M D, Tijssen, J G P, Mulder, B J M

“…OBJECTIVE To investigate liver function and coagulation disorders in patients with a Fontan circulation at different time intervals after surgery. DESIGN…”
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Toll-like receptor-4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia by Netea, M. G., Hijmans, A., Van Wissen, S., Smilde, T. J., Trip, M. D., Kullberg, B. J., De Boo, T., Van der Meer, J. W. M., Kastelein, J. J. P., Stalenhorf, A. F. H.

“…Background  Toll‐like receptor‐4 (TLR4) is a major receptor for inflammatory stimuli potentially involved in the pathogenesis of atherosclerosis, such as…”
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The 20210 G → A mutation in the 3′‐untranslated region of the prothrombin gene and the risk for arterial thrombotic disease by Franco, R. F., Trip, M. D., Ten Cate, H., Van Den Ende, A., Prins, M. H., Kastelein, J. J. P., Reitsma, P. H.

“…A sequence variation in the 3′‐untranslated region of the prothrombin (PT) gene (20210 G → A) was recently claimed to be associated with elevated plasma…”
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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies by Sarwar, Nadeem, Butterworth, Adam S, Freitag, Daniel F, Gregson, John, Willeit, Peter, Gorman, Donal N, Gao, Pei, Saleheen, Danish, Rendon, Augusto, Nelson, Christopher P, Braund, Peter S, Hall, Alistair S, Chasman, Daniel I, Tybjærg-Hansen, Anne, Chambers, John C, Benjamin, Emelia J, Franks, Paul W, Clarke, Robert, Wilde, Arthur A M, Trip, Mieke D, Steri, Maristella, Witteman, Jacqueline C M, Qi, Lu, van der Schoot, C Ellen, de Faire, Ulf, Erdmann, Jeanette, Stringham, Heather M, Koenig, Wolfgang, Rader, Daniel J, Melzer, David, Reich, David, Psaty, Bruce M, Kleber, Marcus E, Panagiotakos, Demosthenes B, Willeit, Johann, Wennberg, Patrik, Woodward, Mark, Adamovic, Svetlana, Rimm, Eric B, Meade, Tom W, Gillum, Richard F, Shaffer, Jonathan A, Hofman, Albert, Onat, Altan, Sundström, Johan, Wassertheil-Smoller, Sylvia, Mellström, Dan, Gallacher, John, Cushman, Mary, Tracy, Russell P, Kauhanen, Jussi, Karlsson, Magnus, Salonen, Jukka T, Wilhelmsen, Lars, Amouyel, Philippe, Cantin, Bernard, Best, Lyle G, Ben-Shlomo, Yoav, Manson, JoAnn E, Davey-Smith, George, de Bakker, Paul I W, O'Donnell, Christopher J, Wilson, James F, Wilson, Anthony G, Assimes, Themistocles L, Jansson, John-Olov, Ohlsson, Claes, Tivesten, Åsa, Ljunggren, Östen, Reilly, Muredach P, Hamsten, Anders, Ingelsson, Erik, Cambien, Francois, Hung, Joseph, Thomas, G Neil, Boehnke, Michael, Schunkert, Heribert, Asselbergs, Folkert W, Kastelein, John J P, Gudnason, Vilmundur, Salomaa, Veikko, Harris, Tamara B, Kooner, Jaspal S, Allin, Kristine H, Nordestgaard, Børge G, Hopewell, Jemma C, Goodall, Alison H, Ridker, Paul M, Hólm, Hilma, Watkins, Hugh, Ouwehand, Willem H, Samani, Nilesh J, Kaptoge, Stephen, Di Angelantonio, Emanuele, Harari, Olivier, Danesh, John

“…Summary Background Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6…”
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Long term survivors of childhood brain cancer have an increased risk for cardiovascular disease by Heikens, Janneke, Ubbink, Mathilde C., van der Pal, Heleen P. J., Bakker, Piet J. M., Fliers, Eric, Smilde, Tineke J., Kastelein, John J. P., Trip, Mieke D.

“…BACKGROUND Cranial irradiation for children with brain tumors frequently leads to neuroendocrine deficiencies. In this controlled study, the authors…”
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Prevalence of hereditary haemochromatosis in premature atherosclerotic vascular disease by FRANCO, R. F, ZAGO, M. A, TRIP, M. D, TEN CATE, H, VAN DEN ENDE, A, PRINS, M. H, KASTELEIN, J. J. P, REITSMA, P. H

“…It has been proposed that iron accumulation may contribute to atherogenesis by increasing free radical formation and oxidative stress. Epidemiological studies…”
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Failure to detect Fabry patients in a cohort of prematurely atherosclerotic males by Vedder, A. C, Gerdes, V. E. A, Poorthuis, B. J. H. M, Helmond, M, Trip, M. D, Aerts, J. M. F. G, Hollak, C. E. M

“…Fabry disease, or α-galactosidase A (α-Gal A) deficiency, is a lysosomal storage disorder in which accumulation of globotriaosylceramide (Gb₃) is thought to be…”
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Familial hypercholesterolemia in children by Rodenburg, J, Vissers, M N, Wiegman, A, Trip, M D, Bakker, H D, Kastelein, John J P

“…This review provides an update on recent advances in the diagnosis and management of children with familial hypercholesterolemia. A large cross-sectional…”
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Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemia by van Dam, M, Zwart, M, de Beer, F, Smelt, A H M, Prins, M H, Trip, M D, Havekes, L M, Lansberg, P J, Kastelein, J J P

“…Background: Fibric acid derivatives and HMG-CoA reductase inhibitors are effective in combination for treating patients with familial dysbetalipoproteinaemia…”
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Incidence, predictability, and pathogenesis of amiodarone-induced thyrotoxicosis and hypothyroidism by Trip, M D, Wiersinga, W, Plomp, T A

“…To determine the incidence and predictability and to elucidate the pathogenesis of amiodarone-induced thyrotoxicosis (AIT) and hypothyroidism (AIH). A…”
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The effect of a common methylenetetrahydrofolate reductase mutation on levels of homocysteine, folate, vitamin B12 and on the risk of premature atherosclerosis by Verhoeff, B.J., Trip, M.D., Prins, M.H., Kastelein, J.J.P., Reitsma, P.H.

“…An increased total plasma homocysteine level is an established risk factor for atherosclerotic vascular disease. The plasma level of homocysteine is influenced…”
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Platelet Hyperreactivity and Prognosis in Survivors of Myocardial Infarction by Trip, Mieke D, Cats, Volkert Manger, van Capelle, Frans J.L, Vreeken, Johan

“…We tested the hypothesis that an increase in spontaneous aggregability of platelets in vitro predicts mortality and coronary events in patients who have…”
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Löffler's endomyocarditis in the idiopathic hypereosinophilic syndrome by Corssmit, E P, Trip, M D, Durrer, J D

“…The idiopathic hypereosinophilic syndrome (HES) is a leukoproliferative disorder characterized by sustained eosinophilia (> 1.5 x 10(9)/l) and (multi-)organ…”
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Differences in intima-media thickness in the carotid and femoral arteries in familial hypercholesterolemic heterozygotes with and without clinical manifestations of cardiovascular disease by Wittekoek, Marianne E., de Groot, Eric, Prins, Martin H., Trip, Mieke D., Büller, Harry R., Kastelein, John J.P.

“…It is unknown whether the variation in severity of cardiovascular disease (CVD), seen in patients with familial hypercholesterolemia (FH), is reflected in the…”
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