Search Results - "TREWHELLA, JILL"
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Small-angle scattering and 3D structure interpretation
Published in Current opinion in structural biology (01-10-2016)“…[Display omitted] •Small-angle scattering (SAS) is a useful constraint in 3D biomolecular modelling.•SAS is especially useful for multi-modular and flexible…”
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Growing a thriving international community for small‐angle scattering through collaboration
Published in Journal of applied crystallography (01-08-2021)“…Small‐angle scattering emerged as a tool for studying noncrystalline structures from early observations around 1930 that there was a relationship between the…”
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Small‐angle scattering for structural biology—Expanding the frontier while avoiding the pitfalls
Published in Protein science (01-04-2010)“…The last decade has seen a dramatic increase in the use of small‐angle scattering for the study of biological macromolecules in solution. The drive for more…”
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Bayesian inference of protein conformational ensembles from limited structural data
Published in PLoS computational biology (01-12-2018)“…Many proteins consist of folded domains connected by regions with higher flexibility. The details of the resulting conformational ensemble play a central role…”
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Benchmarking predictive methods for small-angle X-ray scattering from atomic coordinates of proteins using maximum likelihood consensus data
Published in IUCrJ (01-09-2024)“…Stimulated by informal conversations at the XVII International Small Angle Scattering (SAS) conference (Traverse City, 2017), an international team of experts…”
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The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation
Published in Nucleic acids research (20-04-2015)“…SFPQ, (a.k.a. PSF), is a human tumor suppressor protein that regulates many important functions in the cell nucleus including coordination of long non-coding…”
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different views from small angles
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2008)Get full text
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MULCh: modules for the analysis of small-angle neutron contrast variation data from biomolecular assemblies
Published in Journal of applied crystallography (01-02-2008)“…Small‐angle neutron scattering with contrast variation can fill important gaps in our understanding of biomolecular assemblies, providing constraints that can…”
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Refinement of Multidomain Protein Structures by Combination of Solution Small-Angle X-ray Scattering and NMR Data
Published in Journal of the American Chemical Society (30-11-2005)“…Determination of the 3D structures of multidomain proteins by solution NMR methods presents a number of unique challenges related to their larger molecular…”
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Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis
Published in Nature communications (05-10-2018)“…Porphyromonas gingivalis is a keystone bacterial pathogen of chronic periodontitis. P . gingivalis is unable to synthesise the porphyrin macrocycle and relies…”
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Report of the wwPDB Small-Angle Scattering Task Force: Data Requirements for Biomolecular Modeling and the PDB
Published in Structure (London) (04-06-2013)“…This report presents the conclusions of the July 12–13, 2012 meeting of the Small-Angle Scattering Task Force of the worldwide Protein Data Bank (wwPDB; Berman…”
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Cardiac Myosin-Binding Protein C Decorates F-Actin: Implications for Cardiac Function
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2008)“…Cardiac myosin-binding protein C (cMyBP-C) is an accessory protein of striated muscle sarcomeres that is vital for maintaining regular heart function. Its 4…”
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Refined solution structure of the 82-kDa enzyme malate synthase G from joint NMR and synchrotron SAXS restraints
Published in Journal of biomolecular NMR (01-02-2008)“…Determination of the accurate three-dimensional structure of large proteins by NMR remains challenging due to a loss in the density of experimental restraints…”
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Recent advances in small-angle scattering and its expanding impact in structural biology
Published in Structure (London) (06-01-2022)“…Applications of small-angle scattering (SAS) in structural biology have benefited from continuing developments in instrumentation, tools for data analysis,…”
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Activation of the Retroviral Budding Factor ALIX
Published in Journal of Virology (01-09-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification
Published in The Journal of biological chemistry (16-12-2011)“…Combinations of LIM homeodomain proteins form a transcriptional “LIM code” to direct the specification of neural cell types. Two paralogous pairs of LIM…”
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Phosphorylation-dependent Conformational Transition of the Cardiac Specific N-Extension of Troponin I in Cardiac Troponin
Published in Journal of molecular biology (26-10-2007)“…We present here the solution structure for the bisphosphorylated form of the cardiac N-extension of troponin I (cTnI1-32), a region for which there are no…”
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Biomolecular small-angle scattering: data reproducibility, benchmarking predictive methods and best practice reporting
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2023)“…Abstract only…”
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The Role of Heme Binding by DNA-protective Protein from Starved Cells (Dps) in the Tolerance of Porphyromonas gingivalis to Heme Toxicity
Published in The Journal of biological chemistry (07-12-2012)“…The widely expressed DNA-protective protein from starved-cells (Dps) family proteins are considered major contributors to prokaryotic resistance to stress. We…”
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Growing a thriving international community for small‐angle scattering through collaboration. Corrigendum
Published in Journal of applied crystallography (01-12-2021)“…Errors in the article by Jill Trewhella [J. Appl. Cryst. (2021), 54, 1029–1033] are corrected. Errors in the article by Jill Trewhella [J. Appl. Cryst. (2021),…”
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