Search Results - "TREVANI, A. S."

Desiccating stress‐induced disruption of ocular surface immune tolerance drives dry eye disease by Guzmán, M., Keitelman, I., Sabbione, F., Trevani, A. S., Giordano, M. N., Galletti, J. G.

“…Summary Dry eye is an allegedly autoimmune disorder for which the initiating mechanisms and the targeted antigens in the ocular surface are not known, yet…”
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Promotion of neutrophil apoptosis by TNF-alpha by Salamone, G, Giordano, M, Trevani, A S, Gamberale, R, Vermeulen, M, Schettinni, J, Geffner, J R

“…We examined the ability of TNF-alpha to modulate human neutrophil apoptosis. Neutrophils cultured with TNF-alpha alone undergo a low but significant increase…”
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Benzalkonium chloride breaks down conjunctival immunological tolerance in a murine model by Galletti, J G, Gabelloni, M L, Morande, P E, Sabbione, F, Vermeulen, M E, Trevani, A S, Giordano, M N

“…The impact of topical eye drops with benzalkonium chloride (BAK) as a preservative could involve more than the reported toxic effects on the ocular surface…”
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Effect of Nitric Oxide Donors on Oxygen-Dependent Cytotoxic Responses Mediated by Neutrophils by Andonegui, G, Trevani, A. S, Gamberale, R, Carreras, M. C, Poderoso, J. J, Giordano, M, Geffner, J. R

“…We analyzed the effect of nitric oxide (NO) on oxygen-dependent cytotoxic responses mediated by neutrophils against unopsonized erythrocytes using three NO…”
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Neutrophil apoptosis induced by proteolytic enzymes by Trevani, A S, Andonegui, G, Giordano, M, Nociari, M, Fontán, P, Dran, G, Geffner, J R

“…In this study, we show that three proteolytic enzymes of different specificity-pronase, chymotrypsin, and trypsin-induced a dramatic stimulation of neutrophil…”
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Involvement of nitric oxide in the regulation of peripheral blood leukocyte counts by Geffner, J R, Trevani, A S, de D'Elia, I, Diament, M, Klein, D, Giordano, M

“…A role for nitric oxide (NO) in the regulation of blood leukocyte numbers was examined in BALB/c mice by employing the NO synthase inhibitor NG-nitro…”
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Bacterial DNA activates human neutrophils by a CpG‐independent pathway by Trevani, Analía S., Chorny, Alejo, Salamone, Gabriela, Vermeulen, Mónica, Gamberale, Romina, Schettini, Jorge, Raiden, Silvina, Geffner, Jorge

“…Bacterial DNA stimulates macrophages, monocytes, B lymphocytes, NK cells, and dendritic cells in a CpG‐dependent manner. In this work we demonstrate that…”
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Acidic pH increases the avidity of FcγR for immune complexes by López, D. H., Trevani, A. S., Salamone, G., Andonegui, G., Raiden, S., Giordano, M., Geffner, J. R.

“…Summary The interaction of immunoglobulin G (IgG) antibodies with FcγR constitutes a critical mechanism through which IgG antibody effector functions are…”
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Extracellular Acidification Induces Human Neutrophil Activation by Trevani, Analia S, Andonegui, Graciela, Giordano, Mirta, Lopez, Daniel H, Gamberale, Romina, Minucci, Fernando, Geffner, Jorge R

“…In the current work, we evaluated the effect of extracellular acidification on neutrophil physiology. Neutrophils suspended in bicarbonate-buffered RPMI 1640…”
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Nitric oxide synthase inhibitors enhance plasma levels of corticosterone and ACTH by Giordano, M, Vermeulen, M, Trevani, A S, Dran, G, Andonegui, G, Geffner, J R

“…The role of nitric oxide in the regulation of adrenal steroidogenesis was examined in BALB/c mice by employing the nitric oxide synthase inhibitors NG-nitro…”
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Effect of nitric oxide donors on neutrophil responses induced by immune complexes by Andonegui, G, Trevani, A S, Dran, G, Geffner, J R

“…The present study characterizes the effect of two nitric oxide (NO) donors, S-nitrosoglutathione (GSNO) and sodium nitroprusside (SNP), on the ability of…”
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Extracellular acidic pH modulates oxygen‐dependent cytotoxic responses mediated by polymorphonuclear leucocytes and monocytes by GEFFNER, J. R., TREVANI, A. S., MINNUCCI, F., PALERMO, M. S., MAUGERI, N., ISTURIZ, M. A.

“…SUMMARY In the present study, we compared the ability of human neutrophils and monocytes to display oxygen‐dependent cytotoxic responses at pH 7.4 and 6.2. Our…”
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Activation of human platelets by immune complexes prepared with cationized human IgG by SCHATTNER, M, LAZZARI, M, TREVANI, A. S, MALCHIODI, E, KEMPFER, A. C, ISTURIZ, M. A, GEFFNER, J. R

“…The present study shows that the ability of soluble immune complexes (IC), prepared with human IgG and rabbit IgG antibodies against human IgG, to trigger…”
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Neutrophil cytotoxicity induced by immune complexes prepared with cationized antibodies by Geffner, J R, Trevani, A S, Malchiodi, E, Serebrinsky, G P, Isturiz, M A

“…Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While…”
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Effect of proteolytic enzymes on neutrophil FcγRII activity by TREVANI, A. S, ANDONEGUI, G. A, ISTURIZ, M. A, SCHATNER, M, SEREBRINSKY, G, GEFFNER, J. R

“…Previous studies have demonstrated that the treatment of neutrophils with proteolytic enzymes markedly reduces the expression of receptor III for the Fc…”
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Modulation of Human Neutrophil Apoptosis by Immune Complexes by Gamberale, Romina, Giordano, Mirta, Trevani, Analia S, Andonegui, Graciela, Geffner, Jorge R

“…In the present study we examined whether immune complexes (IC) are able to modulate human neutrophil apoptosis. We observed different effects depending on the…”
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Activation of human neutrophils induced by immune complexes prepared with cationic and anionic fractions of normal IgG antibodies by Trevani, A S, Andonegui, G, Kempfer, C, Malchiodi, E, Geffner, J R

“…The authors have recently shown that the ability of immune complexes (IC) to trigger Fc gamma R-dependent cell responses can be dramatically enhanced when the…”
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Inhibition of human neutrophil apoptosis by platelets by Andonegui, G, Trevani, AS, Lopez, DH, Raiden, S, Giordano, M, Geffner, JR

“…In the absence of appropriate stimuli, polymorphonuclear neutrophils rapidly undergo characteristic changes indicative of programmed cell death or apoptosis…”
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The impact of extracellular acidosis on dendritic cell function by Vermeulen, Mónica Elba, Gamberale, Romina, Trevani, Analía Silvina, Martínez, Diego, Ceballos, Ana, Sabatte, Juan, Giordano, Mirta, Geffner, Jorge Raúl

“…Dendritic cells (DCs) are the most efficient antigen-presenting cells. They are activated in the periphery by conserved pathogen molecules and by inflammatory…”
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Losartan, a selective inhibitor of subtype AT1 receptors for angiotensin II, inhibits the binding of N-formylmethionyl-leucyl-phenylalanine to neutrophil receptors by Raiden, S, Giordano, M, Andonegui, G, Trevani, A S, López, D H, Nahmod, V, Geffner, J R

“…Losartan, a selective antagonist of AT1 receptors for angiotensin II, is widely used clinically to manage hypertension. We report here that losartan markedly…”
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