Search Results - "TRESOLDI, Eleonora"

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    T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8 by Tran, Mai T., Faridi, Pouya, Lim, Jia Jia, Ting, Yi Tian, Onwukwe, Goodluck, Bhattacharjee, Pushpak, Jones, Claerwen M., Tresoldi, Eleonora, Cameron, Fergus J., La Gruta, Nicole L., Purcell, Anthony W., Mannering, Stuart I., Rossjohn, Jamie, Reid, Hugh H.

    Published in Nature communications (25-08-2021)
    “…HLA-DQ8, a genetic risk factor in type I diabetes (T1D), presents hybrid insulin peptides (HIPs) to autoreactive CD4+ T cells. The abundance of spliced…”
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    A minority of proliferating human CD4+ T cells in antigen-driven proliferation assays are antigen specific by Bhattacharjee, Pushpak, Pakusch, Miha, Lacorcia, Matthew, Chiu, Chris Y., Liu, Xin, Tresoldi, Eleonora, Foster, Abby, King, Laura, Cameron, Fergus J., Mannering, Stuart I.

    Published in Frontiers in immunology (28-10-2024)
    “…Antigen-driven T-cell proliferation is often measured using fluorescent dye dilution assays, such as the CFSE-based proliferation assay. Dye dilution assays…”
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    Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells by TRESOLDI, Eleonora, DELL'ALBANI, Ilaria, STABILINI, Angela, JOFRA, Tatiana, VALLE, Andrea, GAGLIANI, Nicola, BONDANZA, Attilio, GRAZIA RONCAROLO, Maria, BATTAGLIA, Manuela

    Published in Haematologica (Roma) (01-09-2011)
    “…The clinical use of ex vivo-expanded T-regulatory cells for the treatment of T-cell-mediated diseases has gained increasing momentum. However, the recent…”
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    Glutamine deamidation does not increase the immunogenicity of C-peptide in people with type 1 diabetes by Foster, Abby, Bhattacharjee, Pushpak, Tresoldi, Eleonora, Pakusch, Miha, Cameron, Fergus J., Mannering, Stuart I.

    “…Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease in which the insulin-producing beta cells are destroyed. While it is clear that full-length…”
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    In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression by Scarlatti, Gabriella, Tresoldi, Eleonora, Björndal, Åsa, Fredriksson, Robert, Colognesi, Claudia, Kui Deng, Hong, Malnati, Mauro S, Plebani, Anna, Siccardi, Antonio G, Littman, Dan R, Maria Fenyö, Eva, Lusso, Paolo

    Published in Nature medicine (01-11-1997)
    “…Following the identification of the C-C chemokines RANTES, MIP-1alpha and MIP-1beta as major human immunodeficiency virus (HIV)-suppressive factors produced by…”
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    Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression by Mfarrej, Bechara, Tresoldi, Eleonora, Stabilini, Angela, Paganelli, Alessia, Caldara, Rossana, Secchi, Antonio, Battaglia, Manuela

    Published in Journal of translational medicine (21-02-2017)
    “…Operational tolerance is an alternative to lifelong immunosuppression after transplantation. One strategy to achieve tolerance is by T regulatory cells. Safety…”
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    Generation of Donor-specific T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation by Petrelli, Alessandra, Tresoldi, Eleonora, Mfarrej, Bechara G, Paganelli, Alessia, Spotti, Donatella, Caldara, Rossana, Secchi, Antonio, Battaglia, Manuela

    Published in Transplantation (01-08-2015)
    “…T regulatory type 1 (Tr1) cell-mediated induction of tolerance in preclinical models of transplantation is remarkably effective. The clinical application of…”
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    Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells by Levings, Megan K., Gregori, Silvia, Tresoldi, Eleonora, Cazzaniga, Sabrina, Bonini, Chiara, Roncarolo, Maria Grazia

    Published in Blood (01-02-2005)
    “…Dendritic cells (DCs) are specialized antigen-presenting cells that monitor the antigenic environment and activate naive T cells. The role of DCs is not only…”
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    Proinsulin C-peptide is a major source of HLA-DQ8 restricted hybrid insulin peptides recognized by human islet-infiltrating CD4+ T cells by Bhattacharjee, Pushpak, Pakusch, Miha, Lacorcia, Matthew, Tresoldi, Eleonora, Rubin, Alan F, Foster, Abby, King, Laura, Chiu, Chris Y, Kay, Thomas W H, Karas, John A, Cameron, Fergus J, Mannering, Stuart I

    Published in PNAS nexus (01-11-2024)
    “…Abstract Type 1 diabetes (T1D) is an autoimmune disease that develops when T cells destroy the insulin-producing beta cells that reside in the pancreatic…”
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    Expanding human T regulatory cells with the mTOR-inhibitor rapamycin by Battaglia, Manuela, Stabilini, Angela, Tresoldi, Eleonora

    “…CD4(+)CD25(+)FOXP3(+) T regulatory (Treg) cells are pivotal for the induction and maintenance of peripheral tolerance in both mice and humans. The possibility…”
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    An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells by Gregori, Silvia, Mangia, Patrizia, Bacchetta, Rosa, Tresoldi, Eleonora, Kolbinger, Frank, Traversari, Catia, Carballido, Josè M, de Vries, Jan E, Korthäuer, Ulf, Roncarolo, Maria-Grazia

    Published in The Journal of experimental medicine (18-04-2005)
    “…The effects of a chimeric monoclonal antibody (chA6 mAb) that recognizes both the RO and RB isoforms of the transmembrane protein tyrosine phosphatase CD45 on…”
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    Cutting Edge: CXCR4 Is a Functional Coreceptor for Infection of Human Macrophages by CXCR4-Dependent Primary HIV-1 Isolates by Verani, Alessia, Pesenti, Elena, Polo, Simona, Tresoldi, Eleonora, Scarlatti, Gabriella, Lusso, Paolo, Siccardi, Antonio G, Vercelli, Donata

    Published in The Journal of immunology (1950) (01-09-1998)
    “…Abstract The identification of HIV-1 coreceptors has provided a molecular basis for the tropism of different HIV-1 strains. CXC chemokine receptor-4 (CXCR4)…”
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    C-C chemokines released by lipopolysaccharide (LPS)-stimulated human macrophages suppress HIV-1 infection in both macrophages and T cells by Verani, A, Scarlatti, G, Comar, M, Tresoldi, E, Polo, S, Giacca, M, Lusso, P, Siccardi, A G, Vercelli, D

    Published in The Journal of experimental medicine (03-03-1997)
    “…Human immunodeficiency virus-1 (HIV-1) expression in monocyte-derived macrophages (MDM) infected in vitro is known to be inhibited by lipopolysaccharide (LPS)…”
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    Human recombinant antibody fragments specific for a rye-grass pollen allergen: Characterization and potential applications by De Lalla, Claudia, Tamborini, Elena, Longhi, Renato, Tresoldi, Eleonora, Manoni, Marco, Siccardi, Antonio G., Arosio, Paolo, Sidoli, Alessandro

    Published in Molecular immunology (01-09-1996)
    “…One of the major allergens from the pollen of perennial rye grass ( Lolium perenne), Lol pII, was used to isolate specific antibody fragments from a random…”
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