Search Results - "TREMBLAY, Sonia"

Polygenic Variation Underlying Educational Attainment and Attention-Deficit/Hyperactivity Disorder Indexes Behavior Ratings of Executive Functions in Child Psychiatry Outpatients by Capawana, Michael R., Vuijk, Pieter J., Martin, Joanna, Pollastri, Alisha R., Forchelli, Gina A., Woscoboinik, Georgia G., Tremblay, Sonia L., Wolfe, Lauren E., Braaten, Ellen B., Doyle, Alysa E.

“…Objective: We leveraged common genetic variation underlying ADHD, educational attainment (EA) and cognition (COG) to understand the nature of the Behavior…”
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Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor by FENWICK, Craig, AMAD, Ma'an, FADER, Lee D, FAUCHER, Anne-Marie, GARNEAU, Michel, JAKALIAN, Araz, KAWAI, Stephen, LAMORTE, Louie, LAPLANTE, Steven, LAIBIN LUO, MASON, Steve, POUPART, Marc-André, BAILEY, Murray D, RIOUX, Nathalie, SCHROEDER, Patricia, SIMONEAU, Bruno, TREMBLAY, Sonia, TSANTRIZOS, Youla, WITVROUW, Myriam, YOAKIM, Christiane, BETHELL, Richard, BÖS, Michael, BONNEAU, Pierre, CORDINGLEY, Michael, COULOMBE, René, DUAN, Jianmin, EDWARDS, Paul

“…BI 224436 is an HIV-1 integrase inhibitor with effective antiviral activity that acts through a mechanism that is distinct from that of integrase strand…”
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Caffeine Delays Ethanol-Induced Sedation in Drosophila by Tremblay, Sonia, Zeng, Yanqiqi, Yue, Aixin, Chabot, Kiana, Mynahan, Abigail, Desrochers, Stephanie, Bridges, Sarra, Ahmad, S Tariq

“…Caffeine and ethanol are among the most widely available and commonly consumed psychoactive substances. Both interact with adenosine receptor-mediated…”
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Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography by Transfiguracion, Julia, Tran, Michelle Yen, Lanthier, Stéphane, Tremblay, Sonia, Coulombe, Nathalie, Acchione, Mauro, Kamen, Amine A.

“…Lentiviral vectors (LVs) are a popular gene delivery tool in cell and gene therapy and they are a primary tool for ex vivo transduction of T cells for…”
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Selection and characterization of HIV-1 showing reduced susceptibility to the non-peptidic protease inhibitor tipranavir by Doyon, Louise, Tremblay, Sonia, Bourgon, Lise, Wardrop, Elizabeth, Cordingley, Michael G.

“…Tipranavir is a novel, non-peptidic protease inhibitor, which possesses broad antiviral activity against multiple protease inhibitor-resistant HIV-1…”
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Symptom-to-door time in ST segment elevation myocardial infarction: Overemphasized or overlooked? Results from the AMI-McGill study by Afilalo, Jonathan, MD, Piazza, Nicolo, MD, Tremblay, Sonia, MD, Soucy, Nathalie, PhD, Huynh, Thao, MD MSC

“…Background Ischemic time is a major determinant of infarct size in ST segment elevation myocardial infarction (STEMI). Emphasis is placed on reducing the…”
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Outcomes in Adults With Bicuspid Aortic Valves by Tzemos, Nikolaos, Therrien, Judith, Yip, James, Thanassoulis, George, Tremblay, Sonia, Jamorski, Michal T, Webb, Gary D, Siu, Samuel C

“…CONTEXT Bicuspid aortic valve is the most common congenital cardiac anomaly in the adult population. Cardiac outcomes in a contemporary population of adults…”
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5.11 Polygenic Risk for ADHD Indexes Behavior Ratings of Executive Functions in Child Psychiatry Outpatients by Capawana, Michael, Vuijk, Pieter, Pollastri, Alisha, Forchelli, Gina, Tremblay, Sonia, Colvin, Molly, Braaten, Ellen, Doyle, Alysa

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52.2 Investigating Specificity and Sex-Dependent Manifestation of Polygenic Risk in a Child Clinical Cohort by Doyle, Alysa E., Vuijk, Pieter J., Genovese, Giulio, Ge, Tian, Capawana, Michael R., Tremblay, Sonia L., O'Dor, Sarah L., Braaten, Ellen B., Martin, Joanna

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Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones cultivated at high cell density by Shen, Chun Fang, Tremblay, Sonia, Sabourin-Poirier, Catherine, Burney, Elodie, Broussau, Sophie, Manceur, Aziza, Rodenbrock, Anja, Voyer, Robert, Loignon, Martin, Ansorge, Sven, Gilbert, Rénald

“…The growing interest in the use of lentiviral vectors (LVs) for various applications has created a strong demand for large quantities of vectors. To meet the…”
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Development of a high-throughput human cytomegalovirus quantitative PCR cell-based assay by Tremblay, Sonia, Dansereau, Nathalie, Balsitis, Scott, Franti, Michael, Lamorte, Louie

“…This report describes the development and optimization of a quantitative real-time PCR assay for evaluating human cytomegalovirus (CMV) replication in vitro…”
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Nucleotide competing reverse transcriptase inhibitors: Discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors by James, Clint A., DeRoy, Patrick, Duplessis, Martin, Edwards, Paul J., Halmos, Teddy, Minville, Joannie, Morency, Louis, Morin, Sébastien, Simoneau, Bruno, Tremblay, Martin, Bethell, Richard, Cordingley, Michael, Duan, Jianmin, Lamorte, Louie, Pelletier, Alex, Rajotte, Daniel, Salois, Patrick, Tremblay, Sonia, Sturino, Claudio F.

“…A HTS screen led to the identification of a benzofurano[3,2-d]pyrimidin-2-one core structure which upon further optimization resulted in 1 as a potent HIV-1…”
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Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors by Tremblay, Martin, Bethell, Richard C., Cordingley, Michael G., DeRoy, Patrick, Duan, Jianmin, Duplessis, Martin, Edwards, Paul J., Faucher, Anne-Marie, Halmos, Ted, James, Clint A., Kuhn, Cyrille, Lacoste, Jean-Éric, Lamorte, Louie, LaPlante, Steven R., Malenfant, Éric, Minville, Joannie, Morency, Louis, Morin, Sébastien, Rajotte, Daniel, Salois, Patrick, Simoneau, Bruno, Tremblay, Sonia, Sturino, Claudio F.

“…Screening of our sample collection led to the identification of a set of benzofurano[3,2-d]pyrimidine-2-one hits acting as nucleotide-competing HIV-1 reverse…”
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Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: In vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors by Sturino, Claudio F., Bousquet, Yves, James, Clint A., DeRoy, Patrick, Duplessis, Martin, Edwards, Paul J., Halmos, Ted, Minville, Joannie, Morency, Louis, Morin, Sébastien, Thavonekham, Bounkham, Tremblay, Martin, Duan, Jianmin, Ribadeneira, Maria, Garneau, Michel, Pelletier, Alex, Tremblay, Sonia, Lamorte, Louie, Bethell, Richard, Cordingley, Michael G., Rajotte, Daniel, Simoneau, Bruno

“…Recently, a new class of HIV reverse transcriptase (HIV-RT) inhibitors has been reported. The novel mechanism of inhibition by this class involves competitive…”
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Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus by Fader, Lee, Brault, Martine, Desjardins, Jessica, Dansereau, Nathalie, Lamorte, Louie, Tremblay, Sonia, Bilodeau, François, Bordeleau, Josée, Duplessis, Martin, Gorys, Vida, Gillard, James, Gleason, James L, James, Clint, Joly, Marc-André, Kuhn, Cyrille, Llinas-Brunet, Montse, Luo, Laibin, Morency, Louis, Morin, Sébastien, Parisien, Mathieu, Poirier, Maude, Thibeault, Carl, Trinh, Thao, Sturino, Claudio, Srivastava, Sanjay, Yoakim, Christiane, Franti, Michael

“…A high-throughput screen based on a viral replication assay was used to identify inhibitors of the human cytomegalovirus. Using this approach, hit compound 1…”
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Construct Validity of the Neurobehavioral Assessment of Preterm Infants by Snider, Laurie, Tremblay, Sonia, Limperopoulos, Cathy, Majnemer, Annette, Filion, Francoise, Johnston, Celeste

“…In this nonrandomized, prospective cohort study, the construct validity of the Neurobehavioral Assessment of the Preterm Infant (NAPI) was examined by…”
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Construct Validity of the Neurobehavioral Assessment of Preterm Infants by Snider, Laurie, Tremblay, Sonia, Limperopoulos, Cathy, Majnemer, Annette, Filion, FrançOise, Johnston, Celeste

“…In this nonrandomized, prospective cohort study, the construct validity of the Neurobehavioral Assessment of the Preterm Infant (NAPI) was examined by…”
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