Search Results - "TREMBLAY, K."
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Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial
Published in Gene therapy (01-04-2013)“…We describe the 2-year follow-up of an open-label trial (CT-AMT-011–01) of AAV1-LPL S447X gene therapy for lipoprotein lipase (LPL) deficiency (LPLD), an…”
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STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner
Published in EMBO molecular medicine (01-05-2017)“…Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial…”
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Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy
Published in Nature communications (13-09-2019)“…The master posttranscriptional regulator HuR promotes muscle fiber formation in cultured muscle cells. However, its impact on muscle physiology and function in…”
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Pharmacological or genetic inhibition of iNOS prevents cachexia‐mediated muscle wasting and its associated metabolism defects
Published in EMBO molecular medicine (07-07-2021)“…Cachexia syndrome develops in patients with diseases such as cancer and sepsis and is characterized by progressive muscle wasting. While iNOS is one of the…”
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Gene expression profiles of recurrent acute pancreatitis risk in severe hypertriglyceridemia
Published in Atherosclerosis (01-09-2016)Get full text
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Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation
Published in Nucleic acids research (24-04-2024)“…Poly(ADP-ribosylation) (PARylation) is a post-translational modification mediated by a subset of ADP-ribosyl transferases (ARTs). Although…”
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The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting
Published in EMBO molecular medicine (01-07-2018)“…Activation of AMPK has been associated with pro‐atrophic signaling in muscle. However, AMPK also has anti‐inflammatory effects, suggesting that in cachexia, a…”
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Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo
Published in Biology of reproduction (01-06-2000)“…The H19 gene is imprinted with preferential expression from the maternal allele. The putative imprinting control region for this locus is hypermethylated on…”
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Investigation of LPL independent pathways of TG-rich lipoprotein metabolism in LPL deficiency
Published in Atherosclerosis (01-09-2016)Get full text
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Dissection of clinical and gene expression signatures of familial vs multifactorial chylomicronemia
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Tracking Inhibitory Control in Youth With ADHD: A Multi-Modal Neuroimaging Approach
Published in Frontiers in psychiatry (19-11-2020)“…A decreased ability to inhibit a speeded motor response is a well-studied deficit in Attention Deficit Hyperactivity Disorder (ADHD), and has been proposed as…”
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Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation
Published in Development (Cambridge) (01-09-2001)“…The Smad proteins are important intracellular mediators of the transforming growth factor β (TGFβ) family of secreted growth factors. Smad1 is an effector of…”
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Test-Retest Reliability of Cortical Evoked Potentials Using Naturally Produced Speech Sounds
Published in Ear and hearing (01-06-2003)“…OBJECTIVETo determine if naturally produced speech stimuli evoke distinct neural response patterns that can be reliably recorded in individuals. DESIGNAuditory…”
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The role of the brain reward system in depression
Published in Progress in neuro-psychopharmacology & biological psychiatry (01-05-2001)“…1. The goal of this review is to familiarize the reader about the potential involvement of the brain reward system (BRS) in symptoms of Major Depressive…”
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The time course of auditory perceptual learning: neurophysiological changes during speech-sound training
Published in Neuroreport (16-11-1998)“…Here we report that training-associated changes in neural activity can precede behavioral learning. This finding suggests that speech-sound learning occurs at…”
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A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development
Published in Molecular and Cellular Biology (01-08-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evoked cortical activity and speech recognition as a function of the number of simulated cochlear implant channels
Published in Clinical neurophysiology (01-04-2009)“…Abstract Objectives (1) To determine if consonant–vowel–consonant (CVC) syllables [Hillenbrand J, Getty L, Clark M, Wheeler K. Acoustic characteristics of…”
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A paternal-specific methylation imprint marks the alleles of the mouse H19 gene
Published in Nature genetics (01-04-1995)“…Imprinting, the differential expression of the two alleles of a gene based on their parental origin, requires that the alleles be distinguished or marked. A…”
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Association study between the CX3CR1 gene and asthma
Published in Genes and immunity (01-12-2006)“…CX3CR1, a fractalkine receptor, mediates cell-adhesive and migratory functions in inflammation. Based on CX3CR1 expression observed in bronchial tissues of…”
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