Search Results - "TREGEAR, G. W"

Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat by Ma, S, Bonaventure, P, Ferraro, T, Shen, P.-J, Burazin, T.C.D, Bathgate, R.A.D, Liu, C, Tregear, G.W, Sutton, S.W, Gundlach, A.L

“…Abstract Relaxin-3 (RLX3) is a newly identified member of the relaxin/insulin peptide family that is highly conserved across a range of species from fish to…”
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Identification of the N-Linked Glycosylation Sites of the Human Relaxin Receptor and Effect of Glycosylation on Receptor Function by Yan, Y, Scott, D. J, Wilkinson, T. N, Ji, J, Tregear, G. W, Bathgate, R. A. D

“…The relaxin receptor, RXFP1, is a member of the leucine-rich repeat-containing G-protein-coupled receptor (LGR) family. These receptors are characterized by a…”
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Comparative localization of leucine-rich repeat-containing G-protein-coupled receptor-7 (RXFP1) mRNA and [33P]-relaxin binding sites in rat brain: Restricted somatic co-expression a clue to relaxin action? by Ma, S., Shen, P.-J., Burazin, T.C.D., Tregear, G.W., Gundlach, A.L.

“…Relaxin is a polypeptide hormone with established actions associated with reproductive physiology, but until recently the precise nature of the relaxin…”
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Characterization of the Mouse and Rat Relaxin Receptors by SCOTT, D J, LAYFIELD, S, RIESEWIJK, A, MORITA, H, TREGEAR, G W, BATHGATE, R A D

“…: Rodent models have been used for many years to probe the actions of relaxin. Identification of the orthologs of human leucine‐rich repeat‐containing…”
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Leucine-rich repeat-containing G-protein-coupled receptor 8 in mature glomeruli of developing and adult rat kidney and inhibition by insulin-like peptide-3 of glomerular cell proliferation by Fu, P, Shen, P-J, Zhao, C-X, Scott, D J, Samuel, C S, Wade, J D, Tregear, G W, Bathgate, R A D, Gundlach, A L

“…Leucine-rich repeat-containing G-protein-coupled receptor 8 (LGR8, or RXFP2) is a member of the type C leucine-rich repeat-containing G protein-coupled…”
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Characterization of the Rat INSL3 Receptor by SCOTT, D J, FU, P, SHEN, P-J, GUNDLACH, A, LAYFIELD, S, RIESEWIJK, A, TOMIYAMA, H, HUTSON, J M, TREGEAR, G W, BATHGATE, R A D

“…: Human LGR8, initially discovered as a low‐affinity relaxin receptor, has now been characterized as the INSL3 receptor. To investigate LGR8 function in the…”
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Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: characterization and effects of oestrogen treatment by Tan, Y Y, Wade, J D, Tregear, G W, Summers, R J

“…The binding characteristics of the relaxin receptor in rat atria, uterus and cortex were studied using a [33P]‐labelled human gene 2 relaxin (B33) and…”
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Collagen Studies in Late Pregnant Relaxin Null Mice by Zhao, L, Samuel, C S, Tregear, G W, Beck, F, Wintour, E M

“…The relaxin knockout (rlx −/−) mouse was used to assess the effect, during pregnancy, of relaxin with regard to water, collagen content, growth, and…”
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LGR7-Truncate Is a Splice Variant of the Relaxin Receptor LGR7 and Is a Relaxin Antagonist in Vitro by SCOTT, D J, TREGEAR, G W, BATHGATE, R A D

“…: The relaxin receptor (LGR7) and the insulin‐like peptide 3 (INSL3) receptor (LGR8) are unique LGR family members in possessing a single, functionally…”
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Comparison of relaxin receptors in rat isolated atria and uterus by use of synthetic and native relaxin analogues by Tan, Y Y., Wade, J D., Tregear, G W., Summers, R J.

“…The receptors for relaxin in the rat atria and uterus were investigated and compared by use of a series of synthetic and native relaxin analogues. The assays…”
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IDENTIFICATION AND CHARACTERIZATION OF THE MOUSE AND RAT RELAXIN RECEPTORS AS THE NOVEL ORTHOLOGUES OF HUMAN LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN-COUPLED RECEPTOR 7 by Scott, DJ, Layfield, S, Riesewijk, A, Morita, H, Tregear, GW, Bathgate, RAD

“…SUMMARY 1. Relaxin is an extracellular matrix (ECM)‐remodelling hormone that is functionally important in reproductive tissues, brain, lung and heart. 2…”
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Location of the Major Antigenic Sites Involved in Rotavirus Serotype-Specific Neutralization by Dyall-Smith, Michael L., Lazdins, Ieva, Tregear, Geoffrey W., Holmes, Ian H.

“…Antigenic sites on the rotavirus major outershell glycoprotein were identified by using mutant viruses selected for resistance to neutralizing…”
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Expression of the relaxin gene in rat tissues by Gunnersen, J.M., Crawford, R.J., Tregear, G.W.

“…The peptide hormone relaxin is produced at high levels in the corpus luteum of the rat ovary during pregnancy. The biological effects of the hormone include…”
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Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family by Bathgate, Ross A D, Samuel, Chrishan S, Burazin, Tanya C D, Layfield, Sharon, Claasz, Antonia A, Reytomas, Irna Grace T, Dawson, Nicola F, Zhao, Chongxin, Bond, Courtney, Summers, Roger J, Parry, Laura J, Wade, John D, Tregear, Geoffrey W

“…We have identified a novel human relaxin gene, designated H3 relaxin, and an equivalent relaxin gene in the mouse from the Celera Genomics data base. Both…”
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Distribution of Fos Immunoreactivity in the Lamina Terminalis and Hypothalamus Induced by Centrally Administered Relaxin in Conscious Rats by McKinley, M. J., Burns, P., Colvill, L. M., Oldfield, B. J., Wade, J. D., Weisinger, R. S., Tregear, G. W.

“…The effect of intracerebroventricular (ICV) injections of synthetic human or rat relaxin (25 or 250 ng) on the distribution of Fos detected…”
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Characterization of two relaxin genes in the chimpanzee by Evans, B A, Fu, P, Tregear, G W

“…Relaxin is a peptide hormone which has a variety of physiological effects on tissues of the reproductive tract as well as other organs such as the heart and…”
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Restricted, but abundant, expression of the novel rat gene‐3 (R3) relaxin in the dorsal tegmental region of brain by Burazin, Tanya C. D., Bathgate, Ross A. D., Macris, Mary, Layfield, Sharon, Gundlach, Andrew L., Tregear, Geoffrey W.

“…Relaxin is a peptide hormone with known actions associated with female reproductive physiology, but it has also been identified in the brain. Only one relaxin…”
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Synthesis, conformation, receptor binding and biological activities of monobiotinylated human insulin-like peptide 3 by Fu, P., Layfield, S., Ferraro, T., Tomiyama, H., Hutson, J., Otvos Jr, L., Tregear, G.W., Bathgate, R.A.D., Wade, J.D.

“…:  Biotin‐avidin immobilization has been routinely used as a tool to study peptide–receptor and peptide–antibody interactions. Biotinylated peptides can also…”
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Bacitracin significantly reduces degradation of peptides in plant cell cultures by Bateman, K.S. (University of Melbourne, Parkville, Australia.), Congiu, M, Tregear, G.W, Clarke, A.E, Anderson, M.A

“…Production of useful peptides using recombinant plant cells is often limited by the stability of the newly translated peptides in the plant expression system…”
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Cloning of cDNA for a stylar glycoprotein associated with expression of self-incompatibility in Nicotiana alata by Anderson, M.A, Cornish, E.C, Mau, S.L, Williams, E.G, Hoggart, R, Atkinson, A, Bonig, I, Grego, B, Simpson, R, Roche, P.J

“…Self-incompatibility in flowering plants is controlled by the S gene. A complementary DNA clone encoding a style protein of Nicotiana alata which segregates…”
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