Search Results - "TRAVASSOS, Luiz R"

Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma by Figueiredo, Carlos R, Azevedo, Ricardo A, Mousdell, Sasha, Resende-Lara, Pedro T, Ireland, Lucy, Santos, Almudena, Girola, Natalia, Cunha, Rodrigo L O R, Schmid, Michael C, Polonelli, Luciano, Travassos, Luiz R, Mielgo, Ainhoa

“…Mounting an effective immune response against cancer requires the activation of innate and adaptive immune cells. Metastatic melanoma is the most aggressive…”
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MIF inhibition as a strategy for overcoming resistance to immune checkpoint blockade therapy in melanoma by de Azevedo, Ricardo A., Shoshan, Einav, Whang, Shanzhi, Markel, Gal, Jaiswal, Ashvin R., Liu, Arthur, Curran, Michael A., Travassos, Luiz R., Bar-Eli, Menashe

“…Immune checkpoint blockade (ICB) has demonstrated an impressive outcome in patients with metastatic melanoma, yet, durable complete response; even with…”
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Extracellular vesicles from Paracoccidioides pathogenic species transport polysaccharide and expose ligands for DC-SIGN receptors by da Silva, Roberta Peres, Heiss, Christian, Black, Ian, Azadi, Parastoo, Gerlach, Jared Q., Travassos, Luiz R., Joshi, Lokesh, Kilcoyne, Michelle, Puccia, Rosana

“…Extracellular vesicles (EVs) mediate non-conventional transport of molecules across the fungal cell wall. We aimed at describing the carbohydrate composition…”
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Therapies and Vaccines Based on Nanoparticles for the Treatment of Systemic Fungal Infections by Kischkel, Brenda, Rossi, Suélen A, Santos, Samuel R, Nosanchuk, Joshua D, Travassos, Luiz R, Taborda, Carlos P

“…Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal therapeutics include polyenes, azoles, and echinocandins. However,…”
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Protein tyrosine phosphorylation and protein tyrosine nitration in redox signaling by Monteiro, Hugo P, Arai, Roberto J, Travassos, Luiz R

“…Reversible phosphorylation of protein tyrosine residues by polypeptide growth factor-receptor protein tyrosine kinases is implicated in the control of…”
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Mortality due to systemic mycoses as a primary cause of death or in association with AIDS in Brazil: a review from 1996 to 2006 by Prado, Marli, da Silva, Marcelo Barbosa, Laurenti, Ruy, Travassos, Luiz R, Taborda, Carlos P

“…Deaths caused by systemic mycoses such as paracoccidioidomycosis, cryptococcosis, histoplasmosis, candidiasis, aspergillosis, coccidioidomycosis and…”
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PLP2-derived peptide Rb4 triggers PARP-1-mediated necrotic death in murine melanoma cells by Maia, Vera S. C., Berzaghi, Rodrigo, Arruda, Denise C., Machado, Fabrício C., Loureiro, Leticia L., Melo, Pollyana M. S., Morais, Alice S., Budu, Alexandre, Travassos, Luiz R.

“…Malignant melanoma is the main cause of death in patients with skin cancer. Overexpression of Proteolipid protein 2 (PLP2) increased tumor metastasis and the…”
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Inhibition of melanoma metastasis by dual‐peptide PLGA NPS by Arruda, Denise Costa, de Oliveira, Thaís Dolzany, Cursino, Patrícia Harume Fukuda, Maia, Vera Susana Carneiro, Berzaghi, Rodrigo, Travassos, Luiz R., Tada, Dayane Batista

“…Despite the positive results observed in vitro and in vivo, clinical trials with bioactive peptides are generally hampered by their fast degradation in the…”
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Fungicidal activity of peptides encoded by immunoglobulin genes by Polonelli, Luciano, Ciociola, Tecla, Sperindè, Martina, Giovati, Laura, D’Adda, Tiziana, Galati, Serena, Travassos, Luiz R., Magliani, Walter, Conti, Stefania

“…Evidence from previous works disclosed the antimicrobial, antiviral, anti-tumour and/or immunomodulatory activity exerted, through different mechanisms of…”
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Experimental Therapy of Paracoccidioidomycosis Using P10-Primed Monocyte-Derived Dendritic Cells Isolated From Infected Mice by Silva, Leandro B R, Taira, Cleison L, Dias, Lucas S, Souza, Ana C O, Nosanchuk, Joshua D, Travassos, Luiz R, Taborda, Carlos P

“…Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin American caused by the thermodimorphic fungi of the genus spp. Notably, a Th1 immune response is…”
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Immunotherapy against Systemic Fungal Infections Based on Monoclonal Antibodies by Boniche, Camila, Rossi, Suélen Andreia, Kischkel, Brenda, Barbalho, Filipe Vieira, Moura, Ágata Nogueira D'Aurea, Nosanchuk, Joshua D, Travassos, Luiz R, Taborda, Carlos Pelleschi

“…The increasing incidence in systemic fungal infections in humans has increased focus for the development of fungal vaccines and use of monoclonal antibodies…”
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Immunomodulatory Protective Effects of Rb9 Cyclic-Peptide in a Metastatic Melanoma Setting and the Involvement of Dendritic Cells by Machado, Fabrício C, Girola, Natália, Maia, Vera S C, Bergami-Santos, Patrícia C, Morais, Alice S, Azevedo, Ricardo A, Figueiredo, Carlos R, Barbuto, José A M, Travassos, Luiz R

“…The cyclic VHCDR3-derived peptide (Rb9) from RebMab200 antibody, directed to a NaPi2B phosphate-transport protein, displayed anti-metastatic melanoma activity…”
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Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo by Massaoka, Mariana H, Matsuo, Alisson L, Figueiredo, Carlos R, Farias, Camyla F, Girola, Natália, Arruda, Denise C, Scutti, Jorge A B, Romoff, Paulete, Favero, Oriana A, Ferreira, Marcelo J P, Lago, João H G, Travassos, Luiz R

“…Malignant melanoma is a deadly type of metastatic skin cancer with increased incidence over the past 30 years. Despite the advanced knowledge on the biology,…”
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Dendritic Cells Primed with Paracoccidioides brasiliensis Peptide P10 Are Therapeutic in Immunosuppressed Mice with Paracoccidioidomycosis by Silva, Leandro B R, Dias, Lucas S, Rittner, Glauce M G, Muñoz, Julián E, Souza, Ana C O, Nosanchuk, Joshua D, Travassos, Luiz R, Taborda, Carlos P

“…Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, with the highest prevalence in Brazil, Colombia, and Venezuela. Fungi of the…”
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Self-Aggregation of Cryptococcus neoformans Capsular Glucuronoxylomannan Is Dependent on Divalent Cations by Nimrichter, Leonardo, Frases, Susana, Cinelli, Leonardo P, Viana, Nathan B, Nakouzi, Antonio, Travassos, Luiz R, Casadevall, Arturo, Rodrigues, Marcio L

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Peptides of the constant region of antibodies display fungicidal activity by Polonelli, Luciano, Ciociola, Tecla, Magliani, Walter, Zanello, Pier Paolo, D'Adda, Tiziana, Galati, Serena, De Bernardis, Flavia, Arancia, Silvia, Gabrielli, Elena, Pericolini, Eva, Vecchiarelli, Anna, Arruda, Denise C, Pinto, Marcia R, Travassos, Luiz R, Pertinhez, Thelma A, Spisni, Alberto, Conti, Stefania

“…Synthetic peptides with sequences identical to fragments of the constant region of different classes (IgG, IgM, IgA) of antibodies (Fc-peptides) exerted a…”
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Therapeutic DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis by Rittner, Glauce M G, Muñoz, Julián E, Marques, Alexandre F, Nosanchuk, Joshua D, Taborda, Carlos P, Travassos, Luiz R

“…Paracoccidioidomycosis (PCM), caused by Paracoccidioides brasiliensis, is the most prevalent invasive fungal disease in South America. Systemic mycoses are the…”
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Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells by da Cunha, Fernanda F M, Mugnol, Katia C U, de Melo, Filipe M, Nascimento, Marta V S Q, de Azevedo, Ricardo A, Santos, Raquel T S, Magalhães, Jéssica A, Miguel, Danilo C, Tada, Dayane B, Mortara, Renato A, Travassos, Luiz R, Arruda, Denise C

“…BRN2 transcription factor is associated with the development of malignant melanoma. The cytotoxic activities and cell death mechanism against B16F10-Nex2 cells…”
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Paracoccidioidomycosis vaccine by Travassos, Luiz R., Taborda, Carlos P.

“…Paracoccidioidomycosis is a granulomatous pulmonary infection that is generally controlled by chemotherapy. The efficacy of treatment, however, is limited by…”
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Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite by Campos, Marco A. S, Almeida, Igor C, Takeuchi, Osamu, Akira, Shizuo, Valente, Eneida P, Procopio, Daniela O, Travassos, Luiz R, Smith, Jason A, Golenbock, Douglas T, Gazzinelli, Ricardo T

“…Glycosylphosphatidylinositol (GPI) anchors and glycoinositolphospholipids (GIPLs) from parasitic protozoa have been shown to exert a wide variety of effects on…”
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