Search Results - "TRAPP, B. D"

NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia by Stys, P. K, Micu, I, Jiang, Q, Coderre, E, Ridsdale, A, Zhang, L, Woulfe, J, Yin, X, Trapp, B. D, McRory, J. E, Rehak, R, Zamponi, G. W, Wang, W

“…Central nervous system myelin is a specialized structure produced by oligodendrocytes that ensheaths axons, allowing rapid and efficient saltatory conduction…”
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Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease by Bjartmar, C, Wujek, J.R, Trapp, B.D

“…Axonal degeneration has been identified as the major determinant of irreversible neurological disability in patients with multiple sclerosis (MS). Axonal…”
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Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS) by Greco, C. M., Berman, R. F., Martin, R. M., Tassone, F., Schwartz, P. H., Chang, A., Trapp, B. D., Iwahashi, C., Brunberg, J., Grigsby, J., Hessl, D., Becker, E. J., Papazian, J., Leehey, M. A., Hagerman, R. J., Hagerman, P. J.

“…Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder that affects carriers, principally males, of premutation…”
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Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration by Bø, L, Vedeler, C A, Nyland, H, Trapp, B D, Mørk, S J

“…The present study examined the extent and distribution of lymphocyte infiltration in demyelinated lesions in the cerebral cortex of multiple sclerosis (MS)…”
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Cortical demyelination in PML and MS : Similarities and differences by MOLL, N. M, RIETSCH, A. M, RANSOHOFF, A. J, COSSOY, M. B, HUANG, D, EICHLER, F. S, TRAPP, B. D, RANSOHOFF, R. M

“…To characterize pathologic changes in the cerebral cortex of patients with multiple sclerosis (MS) and progressive multifocal leukoencephalopathy (PML)…”
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Axonal loss in normal-appearing white matter in a patient with acute MS by BJARTMAR, C, KINKEL, R. P, KIDD, G, RUDICK, R. A, TRAPP, B. D

“…Brain imaging studies detect abnormalities in normal-appearing white matter in patients with MS. To investigate the histopathologic basis for these changes in…”
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Axonal Transection in the Lesions of Multiple Sclerosis by Trapp, Bruce D, Peterson, John, Ransohoff, Richard M, Rudick, Richard, Mörk, Sverre, Bö, Lars

“…Multiple sclerosis is a disease of the central nervous system characterized by multicentric inflammation and destruction of myelin. The primary cause of…”
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NG2+ Glial Cells: A Novel Glial Cell Population in the Adult Brain by Nishiyama, Akiko, Chang, Ansi, Trapp, Bruce D

“…We describe a major glial cell population in the central nervous system (CNS) that can be identified by the expression of 2 cell surface molecules, the NG2…”
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Axon Loss in the Spinal Cord Determines Permanent Neurological Disability in an Animal Model of Multiple Sclerosis by WUJEK, JEROME R, BJARTMAR, CARL, RICHER, EDWARD, RANSOHOFF, RICHARD M, YU, MIN, TUOHY, VINCENT K, TRAPP, BRUCE D

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Most patients undergo an initial relapsing-remitting…”
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Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains by Bö, L, Dawson, T M, Wesselingh, S, Mörk, S, Choi, S, Kong, P A, Hanley, D, Trapp, B D

“…The amount of messenger RNA encoding human inducible nitric oxide synthase and the presence and distribution of NADPH diaphorase were determined in tissue…”
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Heterophilic Binding of L1 on Unmyelinated Sensory Axons Mediates Schwann Cell Adhesion and Is Required for Axonal Survival by Haney, C. A., Sahenk, Z., Li, C., Lemmon, V. P., Roder, J., Trapp, B. D.

“…This study investigated the function of the adhesion molecule L1 in unmyelinated fibers of the peripheral nervous system (PNS) by analysis of L1-deficient…”
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Rat spinal cord neurons contain nitric oxide synthase by Saito, S, Kidd, G J, Trapp, B D, Dawson, T M, Bredt, D S, Wilson, D A, Traystman, R J, Snyder, S H, Hanley, D F

“…We describe the distribution and characteristics of nitric oxide synthase-containing neurons in rat spinal cord using a polyclonal affinity-purified antibody…”
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Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression by Stoll, G, Trapp, BD, Griffin, JW

“…This study examined Wallerian degeneration (WD) of rat optic nerve (ON) with 2 goals: to determine which cell types are involved in myelin degradation and…”
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Affinity-purification and characterization of caveolins from the brain: Differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types by Ikezu, Tsuneya, Ueda, Hideho, Trapp, Bruce D, Nishiyama, Kazutoshi, Sha, Jing Feng, Volonte, Daniela, Galbiati, Ferruccio, Byrd, Anne Lane, Bassell, Gary, Serizawa, Hiroaki, Lane, William S, Lisanti, Michael P, Okamoto, Takashi

“…Caveolins 1, 2 and 3 are the principal protein components of caveolae organelles. It has been proposed that caveolae play a vital role in a number of essential…”
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The Myelin-Associated Glycoprotein Is Enriched in Multivesicular Bodies and Periaxonal Membranes of Actively Myelinating Oligodendrocytes by Trapp, Bruce D., Andrews, S. Brian, Cootauco, Cindy, Quarles, Richard

“…The myelin-associated glycoprotein (MAG) is a member of the immunoglobulin gene superfamily that is selectively expressed by myelin-forming cells. A…”
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Cortical pathology in multiple sclerosis: experimental approaches to studies on the mechanisms of demyelination and remyelination by Staugaitis, S. M., Chang, A., Trapp, B. D.

“…Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of unknown etiology that can involve all parts of the central nervous system and is…”
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Axo-Glial Septate Junctions: The Maestro of Nodal Formation and Myelination? by Trapp, Bruce D., Kidd, Grahame J.

“…The 155kD isoform of neurofascin, an ankyrin binding member of the L1 family, is the first glial constituent of the paranodal axo-glial junction. As the major…”
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Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells by Trapp, BD, Hauer, P, Lemke, G

“…Upon transection of a peripheral nerve, axons distal to the transection degenerate. As a consequence of this axonal degeneration, myelin-forming Schwann cells…”
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Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw by Lam, H.H.D., Hanley, D.F., Trapp, B.D., Saito, S., Raja, S., Dawson, T.M., Yamaguchi, H.

“…The nitric oxide synthase (NOS) inhibitor t,-nitroarginine methyl ester has been found to exhibit antinociceptive activity in a rat model of pain [Kitto, K.F…”
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Cerebral white matter changes in acquired immunodeficiency syndrome dementia: alterations of the blood-brain barrier by Power, C, Kong, P A, Crawford, T O, Wesselingh, S, Glass, J D, McArthur, J C, Trapp, B D

“…The cause of acquired immunodeficiency syndrome (AIDS) dementia, which is a frequent late manifestation of human immunodeficiency virus (HIV) infection, is…”
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