Search Results - "TRAN, T. B"
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New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice
Published in Bioconjugate chemistry (15-04-2020)“…Oxyntomodulin (OXM) is an intestinal peptide hormone that activates both glucagon-like peptide-1 (GLP-1) and glucagon (GCG) receptors. The natural peptide…”
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2
Discovery of CMX990: A Potent SARS-CoV‑2 3CL Protease Inhibitor Bearing a Novel Warhead
Published in Journal of medicinal chemistry (22-02-2024)“…There remains a need to develop novel SARS-CoV-2 therapeutic options that improve upon existing therapies by an increased robustness of response, fewer safety…”
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3
Reliability assessment and updating of notched timber components subjected to environmental and mechanical loading
Published in Engineering structures (01-07-2018)“…•We propose methodology for reliability assessment and updating of notched timber components.•It is able to account for coupled environmental and mechanical…”
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4
Design of Potent and Proteolytically Stable Biaryl-Stapled GLP-1R/GIPR Peptide Dual Agonists
Published in ACS chemical biology (20-05-2022)“…Recent clinical trials have revealed that the chimeric peptide hormones simultaneously activating glucagon-like peptide-1 receptor (GLP-1R) and…”
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5
Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples
Published in BMC cancer (28-01-2019)“…MYCN amplification directly correlates with the clinical course of neuroblastoma and poor patient survival, and serves as the most critical negative prognostic…”
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6
Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant
Published in Proceedings of the National Academy of Sciences - PNAS (11-10-2016)“…A variable region fusion strategy was used to generate an immunosuppressive antibody based on a novel “stalk-knob” structural motif in the ultralong…”
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7
Recombinant Expression and Stapling of a Novel Long-Acting GLP-1R Peptide Agonist
Published in Molecules (Basel, Switzerland) (28-05-2020)“…Owing to their pleiotropic metabolic benefits, glucagon-like peptide-1 receptor (GLP-1R) agonists have been successfully utilized for treating metabolic…”
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8
Multiple cotunneling in large quantum dot arrays
Published in Physical review letters (12-08-2005)“…We investigate the effects of inelastic cotunneling on the electronic transport properties of gold nanoparticle multilayers and thick films at low applied…”
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9
Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levels
Published in Archives of virology (01-09-2015)“…The phenomenon of the reduction in the cell-specific yield with increasing infection cell density (ICD), the cell density effect, is one of the main hurdles…”
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10
Novel Bisaryl Substituted Thiazoles and Oxazoles as Highly Potent and Selective Peroxisome Proliferator-Activated Receptor δ Agonists
Published in Journal of medicinal chemistry (14-01-2010)“…The discovery, synthesis, and optimization of compound 1 from a high-throughput screening hit to highly potent and selective peroxisome proliferator-activated…”
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11
Prevalence of food allergy in Vietnam: comparison of web-based with traditional paper-based survey
Published in The World Allergy Organization journal (23-07-2018)“…Web-based surveys (WBS) are increasingly applied in epidemiological studies as an appealing alternative to traditional survey methods. Rapid data collection,…”
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12
A simple questionnaire to detect chronic kidney disease patients from Long An province screening data in Vietnam
Published in BMC research notes (30-10-2017)“…The prevalence of chronic kidney disease (CKD) in rural Vietnam is unknown. We wished to determine the prevalence of CKD and determine whether a simple…”
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13
Milling of Rice Grains. The Degradation on Three Structural Levels of Starch in Rice Flour Can Be Independently Controlled during Grinding
Published in Journal of agricultural and food chemistry (27-04-2011)“…Whole polished rice grains were ground using cryogenic and hammer milling to understand the mechanisms of degradation of starch granule structure, whole…”
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14
A substance P mediated pathway contributes to 6-hydroxydopamine induced cell death
Published in Neuroscience letters (30-08-2010)“…The neurotoxin 6-hydroxydopamine (6-OHDA) is used to induce dopaminergic cell death, resulting in insufficient striatal dopamine content in the basal ganglia…”
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15
Comparison of ultrasound-assisted and conventional extraction for recovery of pectin from Gac (Momordica cochinchinensis) pulp
Published in Future foods : a dedicated journal for sustainability in food science (01-12-2021)“…•Gac pulp (GP) is a potential source for low-methoxyl pectin.•pH is the most influencing factor for recovery of pectin from GP.•Optimal acidic hot water…”
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16
Statins and risk of cancer: A meta-analysis of randomized, double-blind, placebo-controlled trials
Published in Indian journal of cancer (01-04-2017)“…PURPOSE: Several meta-analyses of randomized controlled trials (RCTs) reported no association between the use of statins and the risk of cancer. However, they…”
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Decline in baculovirus-expressed recombinant protein production with increasing cell density is strongly correlated to impairment of virus replication and mRNA expression
Published in Applied microbiology and biotechnology (01-06-2013)“…The cell density effect is a well-established constraint in the baculovirus–insect cell expression platform, in which cell-specific productivity declines with…”
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Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing
Published in The AAPS journal (01-04-2013)“…We have recently developed a general liquid chromatography-tandem mass spectrometric (LC-MS/MS) method using a stable isotope-labeled (SIL) monoclonal antibody…”
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Correction to “Discovery of CMX990: A Potent SARS-CoV‑2 3CL Protease Inhibitor Bearing a Novel Warhead”
Published in Journal of medicinal chemistry (27-06-2024)Get full text
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20
Copper-catalyzed one-pot domino reactions via C-H bond activation: synthesis of 3-aroylquinolines from 2-aminobenzylalcohols and propiophenones under metal-organic framework catalysis
Published in RSC advances (01-01-2018)“…A Cu (OBA) (BPY) metal-organic framework was utilized as a productive heterogeneous catalyst for the synthesis of 3-aroylquinolines one-pot domino reactions of…”
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