Search Results - "TRÜMPER, L"

SPARC-positive macrophages are the superior prognostic factor in the microenvironment of diffuse large B-cell lymphoma and independent of MYC rearrangement and double-/triple-hit status by Croci, G.A., Au-Yeung, R.K.H., Reinke, S., Staiger, A.M., Koch, K., Oschlies, I., Richter, J., Poeschel, V., Held, G., Loeffler, M., Trümper, L., Rosenwald, A., Ott, G., Spang, R., Altmann, B., Ziepert, M., Klapper, W.

“…Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with respect to outcome. Features of the tumor microenvironment (TME) are associated with…”
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Wnt 5a Signaling Is Critical for Macrophage-Induced Invasion of Breast Cancer Cell Lines by Pukrop, T., Klemm, F., Hagemann, Th, Gradl, D., Schulz, M., Siemes, S., Trümper, L., Binder, C.

“…Interactions between neoplastic and stromal cells contribute to tumor progression. Wnt genes, involved in cell migration and often deregulated in cancers, are…”
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Peripheral T-cell lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by d'Amore, F., Gaulard, P., Trümper, L., Corradini, P., Kim, W.-S., Specht, L., Bjerregaard Pedersen, M., Ladetto, M.

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Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL) by Klapper, W, Stoecklein, H, Zeynalova, S, Ott, G, Kosari, F, Rosenwald, A, Loeffler, M, Trümper, L, Pfreundschuh, M, Siebert, Reiner

“…Recent retrospective studies of heterogeneously treated patients have suggested that chromosomal aberrations of the MYC gene locus indicate an unfavorable…”
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Optimization of rituximab for the treatment of DLBCL (I): dose-dense rituximab in the DENSE-R-CHOP-14 trial of the DSHNHL by Murawski, N., Pfreundschuh, M., Zeynalova, S., Poeschel, V., Hänel, M., Held, G., Schmitz, N., Viardot, A., Schmidt, C., Hallek, M., Witzens-Harig, M., Trümper, L., Rixecker, T., Zwick, C.

“…To improve outcome of elderly patients with diffuse large B-cell lymphoma, dose-dense rituximab was evaluated in the prospective DENSE-R-CHOP-14 trial…”
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Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL by Koch, K., Hoster, E., Ziepert, M., Unterhalt, M., Ott, G., Rosenwald, A., Hansmann, M.L., Bernd, W., Stein, H., Pöschel, V., Dreyling, M., Trümper, L., Löffler, M., Schmitz, N., Hiddemann, W., Pfreundschuh, M., Klapper, W.

“…Histologically, follicular lymphoma (FL) grades 1, 2 and 3A are composed of two distinct cell types, centroblasts and centrocytes. FL grade 3B is composed only…”
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Obesity negatively impacts outcome in elderly female patients with aggressive B‐cell lymphomas treated with R‐CHOP: results from prospective trials of the German high grade non‐Hodgkin's lymphoma trial group by Hohloch, K., Altmann, B., Pfreundschuh, M., Loeffler, M., Schmitz, N., Zettl, F., Ziepert, M., Trümper, L.

“…Summary To study if obesity is a risk factor in elderly patients (>60 years) with aggressive B‐cell lymphoma, the outcomes of 576 elderly patients treated with…”
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WNT5A: a motility-promoting factor in Hodgkin lymphoma by Linke, F, Zaunig, S, Nietert, M M, von Bonin, F, Lutz, S, Dullin, C, Janovská, P, Beissbarth, T, Alves, F, Klapper, W, Bryja, V, Pukrop, T, Trümper, L, Wilting, J, Kube, D

“…Classical Hodgkin lymphoma (cHL) has a typical clinical manifestation, with dissemination involving functionally neighboring lymph nodes. The factors involved…”
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Effect of gloved hand disinfection on hand hygiene before infection-prone procedures on a stem cell ward by Fehling, P., Hasenkamp, J., Unkel, S., Thalmann, I., Hornig, S., Trümper, L., Scheithauer, S.

“…Hand hygiene compliance even before infection-prone procedures (indication 2, ‘before aseptic tasks’, according to the World Health Organization (WHO)) remains…”
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Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia by SCHROERS, R, GRIESINGER, F, TRÜMPER, L, HAASE, D, KULLE, B, KLEIN-HITPASS, L, SELLMANN, L, DÜHRSEN, U, DÜRIG, J

“…Prognostic predictions in B-cell chronic lymphocytic leukemia (B-CLL) at early clinical stage are based on biological disease parameters, such as ZAP-70 and…”
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Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing by Zamò, A, Pischimarov, J, Schlesner, M, Rosenstiel, P, Bomben, R, Horn, H, Grieb, T, Nedeva, T, López, C, Haake, A, Richter, J, Trümper, L, Lawerenz, C, Klapper, W, Möller, P, Hummel, M, Lenze, D, Szczepanowski, M, Flossbach, L, Schreder, M, Gattei, V, Ott, G, Siebert, R, Rosenwald, A, Leich, E

“…Depending on disease stage follicular lymphoma (FL) lack the t(14;18) in ~15–~50% of cases. Nevertheless, most of these cases express BCL2. To elucidate…”
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β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis by KLEMM, F, BLECKMANN, A, KRAMER, F, BEISSBARTH, T, STADELMANN, C, BINDER, C, PUKROP, T, SIAM, L, CHUANG, H. N, RIETKÖTTER, E, BEHME, D, SCHULZ, M, SCHAFFRINSKI, M, SCHINDLER, S, TRÜMPER, L

“…A role of WNT signaling for primary breast cancers of the basal-like subtype and as a predictor of brain metastasis has been described. However, a responsible…”
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Subgrouping of Burkitt lymphoma variants by DNA methylation is driven by an EBV‐associated epigenotype by Glaser, S., Val, C., Wagener, R., Kretzmer, H., Klapper, W., Hummel, M., Ammerpohl, O., Lichter, P., Burkhardt, B., Trümper, L., Mbulaiteye, S.

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Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL Network Phase II Trial by Ferrero, S, Pastore, A, Scholz, C W, Forstpointner, R, Pezzutto, A, Bergmann, L, Trümper, L, Finke, J, Keller, U, Ghione, P, Passera, R, Hiddemann, W, Weigert, O, Unterhalt, M, Dreyling, M

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Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma by Linke, F, Harenberg, M, Nietert, M M, Zaunig, S, von Bonin, F, Arlt, A, Szczepanowski, M, Weich, H A, Lutz, S, Dullin, C, Janovská, P, Krafčíková, M, Trantírek, L, Ovesná, P, Klapper, W, Beissbarth, T, Alves, F, Bryja, V, Trümper, L, Wilting, J, Kube, D

“…The interaction between vascular endothelial cells (ECs) and cancer cells is of vital importance to understand tumor dissemination. A paradigmatic cancer to…”
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F16 Aggressive lymphoma: How to characterize and treat elderly patients non fit for standard treatment by Trümper, L

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Excellent outcome of young adults with aggressive non-Hodgkin lymphomas treated with CHOP-like regimens by Hohloch, K, Zeynalova, S, Held, G, Ziepert, M, Loeffler, M, Wulf, G, Schmitz, N, Pfreundschuh, M, Trümper, L

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Role and responsibility of oncologists in assisted suicide. Practice and views among members of the German Society of Haematology and Medical Oncology by Schildmann, J., Junghanss, C., Oldenburg, M., Schuler, U., Trümper, L., Wörmann, B., Winkler, E.

“…Physician-assisted suicide (PAS) is a controversial practice and regulatory frameworks differ regarding assigned physicians' roles. This study explores…”
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STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis by HOLTICK, U, VOCKERODT, M, TRÜMPER, L, KUBE, D, PINKERT, D, SCHOOF, N, STÜRZENHOFECKER, B, KUSSEBI, N, LAUBER, K, WESSELBORG, S, LÖFFLER, D, HORN, F

“…Classical Hodgkin lymphoma (cHL) is a distinct malignancy of the immune system. Despite the progress made in the understanding of the biology of cHL, the…”
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Allogeneic transplantation in T‐cell lymphoma: Lessons from the AATT study by Tournilhac, O., Altmann, B., Friedrichs, B., Bouabdallah, K., Cartron, G., Nickelsen, M., Wulf, G., Leclerc, M., Vilatte, A., Turlure, P., Sanhès, L., Houot, R., Roussel, M., Leval, L., Rosenwald, A., Gaulard, P., Dreger, P., Glass, B., Latière, C., Damaj, G., Lenz, G., Reimer, P., Banos, A., Bilger, K., Durot, E., Sibon, D., Wagner, E., Nguyen, S., Trümper, L., Ziepert, M., Schmitz, N.

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