Search Results - "TOYAMA, H"

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures by Toyama, Brandon H., Savas, Jeffrey N., Park, Sung Kyu, Harris, Michael S., Ingolia, Nicholas T., Yates, John R., Hetzer, Martin W.

“…Intracellular proteins with long lifespans have recently been linked to age-dependent defects, ranging from decreased fertility to the functional decline of…”
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Amyloid Structure: Conformational Diversity and Consequences by Toyama, Brandon H, Weissman, Jonathan S

“…Many, perhaps most, proteins, are capable of forming self-propagating, β-sheet (amyloid) aggregates. Amyloid-like aggregates are found in a wide range of…”
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Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain by Savas, Jeffrey N., Toyama, Brandon H., Xu, Tao, Yates, John R., Hetzer, Martin W.

“…To combat the functional decline of the proteome, cells use the process of protein turnover to replace potentially impaired polypeptides with new functional…”
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Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells by Toyama, Brandon H, Arrojo E Drigo, Rafael, Lev-Ram, Varda, Ramachandra, Ranjan, Deerinck, Thomas J, Lechene, Claude, Ellisman, Mark H, Hetzer, Martin W

“…Many adult tissues contain postmitotic cells as old as the host organism. The only organelle that does not turn over in these cells is the nucleus, and its…”
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The physical basis of how prion conformations determine strain phenotypes by Weissman, Jonathan S, Tanaka, Motomasa, Collins, Sean R, Toyama, Brandon H

“…A principle that has emerged from studies of protein aggregation is that proteins typically can misfold into a range of different aggregated forms. Moreover,…”
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structural basis of yeast prion strain variants by Toyama, B.H, Kelly, M.J.S, Gross, J.D, Weissman, J.S

“…Among the many surprises to arise from studies of prion biology, perhaps the most unexpected is the strain phenomenon whereby a single protein can misfold into…”
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Visualization of Lenticulostriate Arteries on CT Angiography Using Ultra-High-Resolution CT Compared with Conventional-Detector CT by Murayama, K, Suzuki, S, Nagata, H, Oda, J, Nakahara, I, Katada, K, Fujii, K, Toyama, H

“…The newly developed ultra-high-resolution CT is equipped with a 0.25-mm detector, which has one-half the conventional section thickness, one-half the in-plane…”
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A single-arm, phase II trial of neoadjuvant gemcitabine and S1 in patients with resectable and borderline resectable pancreatic adenocarcinoma: PREP-01 study by Motoi, Fuyuhiko, Satoi, Sohei, Honda, Goro, Wada, Keita, Shinchi, Hiroyuki, Matsumoto, Ippei, Sho, Masayuki, Tsuchida, Akihiko, Unno, Michiaki

“…Background Neoadjuvant chemotherapy (NAC) represents a promising alternative to pancreatic ductal adenocarcinoma (PDAC) planned resection, but the survival…”
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Gastrointestinal: A case of a pancreatobiliary‐type intraductal papillary mucinous neoplasm of the pancreas filling the main pancreatic duct without visible mucin secretion by Nakano, R, Sakai, A, Kobayashi, T, Masuda, A, Shiomi, H, Toyama, H, Ito, T, Kodama, Y

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Accurate analysis of two-dimensional electromagnetic scattering from multilayered periodic arrays of circular cylinders using lattice sums technique by Yasumoto, K., Toyama, H., Kushta, T.

“…A very efficient and accurate method to characterize two-dimensional (2-D) electromagnetic scattering from multilayered periodic arrays of parallel circular…”
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The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant Enterolobium contortisiliquum; A Case of Two Soul Mates Meeting by Costa, Caroline R C, Belchor, Mariana N, Roggero, Airam, Moraes, Laila L, Samelo, Ricardo, Annunciato, Isabelly, Bonturi, Camila R, Oliva, Maria L V, Sousa, Sergio F, de Oliveira, Marcos A, Toyama, Marcos H

“…Snake venom serine protease (SVSP) interferes with the regulation and control of important biological reactions in homeostasis and can be classified as an…”
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Differences in prion strain conformations result from non-native interactions in a nucleus by Tanaka, Motomasa, Ohhashi, Yumiko, Ito, Kazuki, Toyama, Brandon H, Weissman, Jonathan S

“…The prion strain phenomenon states that distinct amyloid conformations with different phenotypes and heritable states can arise from a single polypeptide. The…”
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L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis by Morais, Isabel C O, Pereira, Gustavo J S, Orzáez, M, Jorge, Roberta J B, Bincoletto, Claudia, Toyama, Marcos H, Monteiro, Helena S A, Smaili, Soraya S, Pérez-Payá, Enrique, Martins, Alice M C

“…Acute renal failure is a common complication caused by Bothrops viper envenomation. In this study, the nefrotoxicity of a main component of B. leucurus venom…”
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Do Perineuronal Nets Stabilize the Engram of a Synaptic Circuit? by Lev-Ram, Varda, Lemieux, Sakina Palida, Deerinck, Thomas J, Bushong, Eric A, Perez, Alex J, Pritchard, Denise R, Toyama, Brandon H, Park, Sung Kyu R, McClatchy, Daniel B, Savas, Jeffrey N, Whitney, Michael, Adams, Stephen R, Ellisman, Mark H, Yates, 3rd, John, Tsien, Roger Y

“…Perineuronal nets (PNNs), a specialized form of extra cellular matrix (ECM), surround numerous neurons in the CNS and allow synaptic connectivity through holes…”
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Non-Clinical Studies for Evaluation of 8-C-Rhamnosyl Apigenin Purified from Peperomia obtusifolia against Acute Edema by Tamayose, Cinthia I, Romoff, Paulete, Toyama, Daniela O, Gaeta, Henrique H, Costa, Caroline R C, Belchor, Mariana N, Ortolan, Bruna D, Velozo, Leosvaldo S M, Kaplan, Maria A C, Ferreira, Marcelo J P, Toyama, Marcos H

“…Compound 8- -rhamnosyl apigenin (8CR) induced a moderate reduction in the enzymatic activity of secretory phospholipase A2 (sPLA2) from and cytosolic…”
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Quinoproteins: structure, function, and biotechnological applications by MATSUSHITA, K, TOYAMA, H, YAMADA, M, ADACHI, O

“…A new class of oxidoreductase containing an amino acid-derived o-quinone cofactor, of which the most typical is pyrroloquinoline quinone (PQQ), is called…”
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Spermatogenesis, Spermatophore, and Seminal Fluid Production in the Adult Blue Crab Callinestes danae (Portunidae) by Zara, Fernando J, Toyama, Marcos H, Caetano, Flávio H, López-Greco, Laura S

“…Sperm and spermatophore production in Callinectes danaeSmith, 1869 were examined by histochemistry and correlated with gonadosomatic (GSI) and hepatosomatic…”
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Radiation Therapy for Symptomatic Bone Metastases: The Effect of Calculated Dose and Dose Distribution on Intensity of Pain Relief and Time of Pain Relief by Kobayashi, H, Ito, F, Oie, Y, Hattori, H, Ito, K, Saito, Y, Toyama, H

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Total tumour volume as a prognostic factor in patients with resectable colorectal cancer liver metastases by Tai, K., Komatsu, S., Sofue, K., Kido, M., Tanaka, M., Kuramitsu, K., Awazu, M., Gon, H., Tsugawa, D., Yanagimoto, H., Toyama, H., Murakami, S., Murakami, T., Fukumoto, T.

“…Background Although total tumour volume (TTV) may have prognostic value for hepatic resection in certain solid cancers, its importance in colorectal liver…”
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630 Radiation therapy for symptomatic bone metastases: The effect of minimum, mean, and maximum doses in PTV by Kobayashi, H, Toyama, H, Hattori, H, Ito, F, Saito, Y, Ito, M, Oie, Y, Hayshi, S

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