Search Results - "TOWNSEND, James C"

An antibody against the surfactant protein A (SP-A)-binding domain of the SP-A receptor inhibits T cell-mediated immune responses to Mycobacterium tuberculosis by Samten, Buka, Townsend, James C., Sever‐Chroneos, Zvjezdana, Pasquinelli, Virginia, Barnes, Peter F., Chroneos, Zissis C.

“…Surfactant protein A (SP‐A) suppresses lymphocyte proliferation and IL‐2 secretion, in part, by binding to its receptor, SP‐R210. However, the mechanisms…”
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A Method for Developing Trustworthiness and Preserving Richness of Qualitative Data During Team-Based Analysis of Large Data Sets by Abraham, Traci H., Finley, Erin P., Drummond, Karen L., Haro, Elizabeth K., Hamilton, Alison B., Townsend, James C., Littman, Alyson J., Hudson, Teresa

“…This article outlines a three-phase, team-based approach used to analyze qualitative data from a nation-wide needs assessment of access to Veteran Health…”
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Time and Organizational Cost for Facilitating Implementation of Primary Care Mental Health Integration by Ritchie, Mona J., Kirchner, JoAnn E., Townsend, James C., Pitcock, Jeffery A., Dollar, Katherine M., Liu, Chuan-Fen

“…Background Integrating mental health services into primary care settings is complex and challenging. Although facilitation strategies have successfully…”
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Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide by Landes, Sara J, Matarazzo, Bridget B, Pitcock, Jeffery A, Drummond, Karen L, Smith, Brandy N, Kirchner, JoAnn E, Clark, Kaily A, Gerard, Georgia R, Jankovsky, Molly C, Brenner, Lisa A, Reger, Mark A, Eagan, Aaron E, Raciborski, Rebecca, Painter, Jacob, Townsend, James C, Jegley, Susan M, Singh, Rajinder Sonia, Trafton, Jodie A, McCarthy, John F, Katz, Ira R

“…In 2017, the Veterans Health Administration (VHA) implemented a national suicide prevention program, called Recovery Engagement and Coordination for…”
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Characteristics and Context of Veterans Experiencing Serious Suicidal Ideation or Suicide Attempt by Firearm which led to Hospitalization by Waliski, Angie, Matthieu, Monica M, Townsend, James C, McGaugh, Janette, Adkins, David A, Skaggs, Elisabeth M, Allison, M Kathryn, Kirchner, JoAnn

“…Suicide by former United States military service members is of great public health concern, and one area, veterans' suicide attempts involving firearms, is…”
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The Mycobacterium tuberculosis Early Secreted Antigenic Target of 6 kDa Inhibits T Cell Interferon-γ Production through the p38 Mitogen-activated Protein Kinase Pathway by Peng, Hui, Wang, Xisheng, Barnes, Peter F., Tang, Hua, Townsend, James C., Samten, Buka

“…We reported previously that the early secreted antigenic target of 6 kDa (ESAT-6) from Mycobacterium tuberculosis directly inhibits human T cell IFN-γ…”
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ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells by Wang, Xisheng, Barnes, Peter F, Dobos-Elder, Karen M, Townsend, James C, Chung, Yoon-tae, Shams, Homayoun, Weis, Stephen E, Samten, Buka

“…The Mycobacterium tuberculosis early secreted Ag of 6 kDa (ESAT-6) is a potent Ag for human T cells and is a putative vaccine candidate. However, ESAT-6 also…”
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CREB, ATF, and AP-1 transcription factors regulate IFN-gamma secretion by human T cells in response to mycobacterial antigen by Samten, Buka, Townsend, James C, Weis, Steven E, Bhoumik, Anindita, Klucar, Peter, Shams, Homayoun, Barnes, Peter F

“…IFN-gamma production by T cells is pivotal for defense against many pathogens, and the proximal promoter of IFN-gamma, -73 to -48 bp upstream of the…”
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IFN-γ Production during Active Tuberculosis Is Regulated by Mechanisms That Involve IL-17, SLAM, and CREB by Pasquinelli, Virginia, Townsend, James C., Jurado, Javier O., Alvarez, Ivana B., Quiroga, María F., Barnes, Peter F., Samten, Buka, García, Verónica E.

“…Interferon-γ (IFN–γ) is crucial for protection against Mycobacterium tuberculosis and the transcription factor cAMP response element binding protein (CREB)…”
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Understanding Veteran Suicide by Firearm by Waliski, Angie, Matthieu, Monica M., Townsend, James C., McGaugh, Janette, Kirchner, JoAnna

“…  Suicide is the 10th leading cause of death with 42,773 reported deaths in the United States in 2014, half of those by firearm. Although veterans comprise…”
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Cyclic AMP response element-binding protein positively regulates production of IFN-gamma by T cells in response to a microbial pathogen by Samten, Buka, Howard, Susan T, Weis, Steven E, Wu, Shiping, Shams, Homayoun, Townsend, James C, Safi, Hassan, Barnes, Peter F

“…IFN-gamma is essential for resistance to many intracellular pathogens, including Mycobacterium tuberculosis. Transcription of the IFN-gamma gene in activated T…”
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Interaction of PvALF and VP1 B3 domains with the beta-phaseolin promoter by Carranco, R, Chandrasekharan, M.B, Townsend, J.C, Hall, T.C

“…The phas promoter is potently transcribed during embryogenesis but in vegetative tissues it is completely silenced by a rotationally positioned nucleosome…”
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ESAT-6 inhibits IFN-γ secretion by Mycobacterium tuberculosis responsive-human T cells (129.12) by Wang, Xisheng, Barnes, Peter F, Townsend, James C, Chung, Yoon-tae, Shams, Homayoun, Samten, Buka

“…Early secreted antigenic target of 6 kD (ESAT-6) of Mycobacterium tuberculosis (M. tb) is a potent antigen with vaccine potential, but is also a virulence…”
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CREB, ATF AND AP-1 TRANSCRIPTION FACTORS REGULATE IFN-γ SECRETION BY HUMAN T CELLS IN RESPONSE TO MYCOBACTERIAL ANTIGEN1 by Samten, Buka, Townsend, James C., Weis, Steven E., Bhoumik, Anindita, Klucar, Peter, Shams, Homayoun, Barnes, Peter F.

“…IFN-γ production by T cells is pivotal for defense against many pathogens, and the proximal promoter of IFN-γ, −73 to −48 bp upstream of the transcription…”
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ESAT-6 Inhibits Production of IFN-γ by Mycobacterium tuberculosis-Responsive Human T Cells1 by Wang, Xisheng, Barnes, Peter F., Dobos-Elder, Karen M., Townsend, James C., Chung, Yoon-tae, Shams, Homayoun, Weis, Stephen E., Samten, Buka

“…The Mycobacterium tuberculosis early secreted Ag of 6 kDa (ESAT-6) is a potent Ag for human T cells and is a putative vaccine candidate. However, ESAT-6 also…”
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cAMP response element binding protein (CREB), activating transcription factor (ATF)-2 and c-Jun bind to the IFN-γ proximal promoter in response to M. tuberculosis (TB) stimulation (43.13) by Samten, Buka, Townsend, James C., Weis, Stephen E., Barnes, Peter F.

“…The proximal promoter controls transcription of IFN-γ in T cells, which is central for defense against many pathogens. By performing EMSA and supershift assays…”
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IFN- Production during Active Tuberculosis Is Regulated by Mechanisms That Involve IL-17, SLAM, and CREB by Pasquinelli, Virginia, Townsend, James C, Jurado, Javier O, Alvarez, Ivana B, Quiroga, Maria F, Barnes, Peter F, Samten, Buka, Garcia, Veronica E

“…Interferon- (IFN-) is crucial for protection against Mycobacterium tuberculosis, and the transcription factor cAMP response element binding protein (CREB)…”
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IFN-y Production during Active Tuberculosis Is Regulated by Mechanisms That Involve IL-17, SLAM, and CREB by PASQUINELLI, Virginia, TOWNSEND, James C, JURADO, Javier O, ALVAREZ, Ivana B, QUIROGA, Maria F, BARNES, Peter F, SAMTEN, Buka, GARCIA, Veronica E

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Elevated cyclic AMP Acts through PKA type I to Inhibit Mycobacterium tuberculosis ‐induced IFN‐γ Secretion by T cells by Chung, Yoontae, Barnes, Peter F., Wang, Xisheng, Townsend, James C., Pasquinelli, Virginia, Jurado, Javier O., Garcia, Veronica E., Weis, Stephen, Samten, Buka

“…Abstract only IFN‐γ secretion is reduced in human tuberculosis (TB), but the underlying mechanisms are unclear. Intracellular cAMP in PBMC from TB patients was…”
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Delay point schedules for irregular parallel computations by NICOL, D. M, SALTZ, J. H, TOWNSEND, J. C

“…In irregular scientific computational problems, it is periodically necessary to choose a delay point where some overhead cost is suffered to ensure correctness…”
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