Search Results - "TOTH, K."
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Functional characterization and related evolutionary implications of invertebrate gonadotropin-releasing hormone/corazonin in a well-established model species
Published in Scientific reports (11-05-2021)“…In vertebrates, gonadotropin-releasing hormone (GnRH) peptide is the central mediator of reproduction. Homologous peptides have previously also been identified…”
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Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes
Published in Life sciences (1973) (01-03-2021)“…During oxidative stress mitochondria become the main source of endogenous reactive oxygen species (ROS) production. In the present study, we aimed to clarify…”
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The Neosartorya fischeri Antifungal Protein 2 (NFAP2): A New Potential Weapon against Multidrug-Resistant Candida auris Biofilms
Published in International journal of molecular sciences (14-01-2021)“…is a potential multidrug-resistant pathogen able to persist on indwelling devices as a biofilm, which serve as a source of catheter-associated infections…”
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Biofungicidal Potential of Neosartorya ( Aspergillus ) Fischeri Antifungal Protein NFAP and Novel Synthetic γ-Core Peptides
Published in Frontiers in microbiology (13-05-2020)“…Because of enormous crop losses worldwide due to pesticide-resistant plant pathogenic fungi, there is an increasing demand for the development of novel…”
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Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP
Published in Journal of natural products (Washington, D.C.) (28-04-2023)“…Emerging fungal infections require new, more efficient antifungal agents and therapies. AFP, a protein from Aspergillus giganteus with four disulfide bonds, is…”
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Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
Published in Antioxidants (06-04-2017)“…The importance of the tumor microenvironment for cancer progression and therapeutic resistance is an emerging focus of cancer biology. Hypoxia, or low oxygen,…”
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Gottfried Konecny: the ambassador of photogrammetry and remote sensing for 75 years
Published in Geo-spatial information science (02-01-2021)“…A 90th birthday would be a milestone celebration for any person, but exceptionally rare if the person is still active after 75 years of working and serving the…”
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Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor
Published in British journal of cancer (16-02-2010)“…Background and aims: Treatment of colorectal adenomas with selective cyclooxygenase-2 inhibitors can contribute to the chemoprevention of colorectal cancer…”
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Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease
Published in Clinical hemorheology and microcirculation (2012)“…Several beneficial effects of resveratrol (RES), a natural antioxidant present in red wine have already been described. The aim of our study was to investigate…”
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Threat of establishment of non-indigenous potato blackleg and tuber soft rot pathogens in Great Britain under climate change
Published in PloS one (12-10-2018)“…Potato blackleg and soft rot caused by Pectobacterium and Dickeya species are among the most significant bacterial diseases affecting potato production…”
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Application of alicyclic beta-amino acids in peptide chemistry
Published in Chemical Society reviews (01-04-2006)“…The self-organizing beta-peptides have attracted considerable interest in the fields of foldamer chemistry and biochemistry. These compounds exhibit various…”
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Aromatic Cluster Sensor of Protein Folding: Near-UV Electronic Circular Dichroism Bands Assigned to Fold Compactness
Published in Chemistry : a European journal (19-09-2016)“…Both far‐ and near‐UV electronic circular dichroism (ECD) spectra have bands sensitive to thermal unfolding of Trp and Tyr residues containing proteins. Beside…”
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The Evolutionary Conserved γ-Core Motif Influences the Anti- Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF
Published in Frontiers in microbiology (20-07-2018)“…Small, cysteine-rich and cationic antimicrobial proteins (AMPs) from filamentous ascomycetes represent ideal bio-molecules for the development of…”
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Interplay between synchronization of multivesicular release and recruitment of additional release sites support short-term facilitation at hippocampal mossy fiber to CA3 pyramidal cells synapses
Published in The Journal of neuroscience (13-08-2014)“…Synaptic short-term plasticity is a key regulator of neuronal communication and is controlled via various mechanisms. A well established property of mossy…”
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Solution Structure, Dynamics, and New Antifungal Aspects of the Cysteine-Rich Miniprotein PAFC
Published in International journal of molecular sciences (25-01-2021)“…The genome of Q176 contains a gene coding for the 88-amino-acid (aa)-long glycine- and cysteine-rich antifungal protein C (PAFC). After maturation, the…”
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Symbiotic NCR Peptide Fragments Affect the Viability, Morphology and Biofilm Formation of Candida Species
Published in International journal of molecular sciences (01-04-2021)“…The increasing rate of fungal infections causes global problems not only in human healthcare but agriculture as well. To combat fungal pathogens limited…”
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Anti-Candidal Activity and Functional Mapping of Recombinant and Synthetic Neosartorya fischeri Antifungal Protein 2 (NFAP2)
Published in Frontiers in microbiology (07-03-2018)“…The increasing number of life-threatening infections caused by antifungal drug-resistant strains urges the development of new therapeutic strategies. The…”
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Rational Design of Antifungal Peptides Based on the γ‑Core Motif of a Neosartorya (Aspergillus) fischeri Antifungal Protein to Improve Structural Integrity, Efficacy, and Spectrum
Published in ACS omega (13-02-2024)“…Antifungal peptides offer promising alternative compounds for the treatment of fungal infections, for which new antifungal compounds are urgently needed…”
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Stability Test of PACAP in Eye Drops
Published in Journal of molecular neuroscience (01-08-2021)“…PACAP is a neuropeptide with widespread distribution and diverse biological functions. It has strong cytoprotective effects mediated mainly through specific…”
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The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans
Published in Journal of fungi (Basel) (01-09-2020)“…Small, cysteine-rich and cationic antimicrobial proteins (AMPs) from filamentous ascomycetes promise treatment alternatives to licensed antifungal drugs. In…”
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