Search Results - "TORMAY, Peter"

Comparison of the Moonlighting Actions of the Two Highly Homologous Chaperonin 60 Proteins of Mycobacterium tuberculosis by Cehovin, Ana, Coates, Anthony R.M, Hu, Yanmin, Riffo-Vasquez, Yanira, Tormay, Peter, Botanch, Catherine, Altare, Frederic, Henderson, Brian

“…Evidence is emerging that the two chaperonin (Cpn) 60 proteins of Mycobacterium tuberculosis, Cpn60.1 and Cpn60.2, have moonlighting actions that may…”
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Mycobacterium tuberculosis Mutant Lacking the groEL Homologue cpn60.1 Is Viable but Fails To Induce an Inflammatory Response in Animal Models of Infection by Hu, Yanmin, Henderson, Brian, Lund, Peter A, Tormay, Peter, Ahmed, M. Tabish, Gurcha, Sudagar S, Besra, Gurdyal S, Coates, Anthony R.M

“…The causative agent of tuberculosis, Mycobacterium tuberculosis, has two chaperonin (Cpn60) proteins and one cochaperonin (Cpn10) protein. We show here that…”
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Big Data in Pharmaceutical R&D: Creating a Sustainable R&D Engine by Tormay, Peter

“…Over the last 20 years, productivity in the pharmaceutical industry has been diminishing because of constantly increasing costs while output has overall been…”
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The Intercellular Signaling Activity of the Mycobacterium tuberculosis Chaperonin 60.1 Protein Resides in the Equatorial Domain by Tormay, Peter, Coates, Anthony R.M., Henderson, Brian

“…The major heat shock protein, chaperonin 60, has been established to have intercellular signaling activity in addition to its established protein-folding…”
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Mycobacterium tuberculosisChaperonin 60.1 Is a More Potent Cytokine Stimulator than Chaperonin 60.2 (Hsp 65) and Contains a CD14-Binding Domain by Lewthwaite, Jo C., Coates, Anthony R. M., Tormay, Peter, Singh, Mahavir, Mascagni, Paolo, Poole, Stephen, Roberts, Michael, Sharp, Lindsay, Henderson, Brian

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bacterial selenocysteine synthase by Tormay, Peter, Wilting, Reinhard, Lottspeich, Friedrich, Mehta, Perdeep K., Christen, Philipp, Böck, August

“…Selenocysteine synthase from Escherichia coli is a pyridoxal‐5′‐phosphate‐containing enzyme which catalyses the conversion of seryl‐tRNASec into…”
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Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection by Stewart, Graham R, Snewin, Valerie A, Walzl, Gerhard, Hussell, Tracy, Tormay, Peter, O'Gaora, Peadar, Goyal, Madhu, Betts, Joanna, Brown, Ivor N, Young, Douglas B

“…Elevated expression of heat-shock proteins (HSPs) can benefit a microbial pathogen struggling to penetrate host defenses during infection, but at the same time…”
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Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain by LEWTHWAITE, Jo. C, COATES, Anthony R. M, TORMAY, Peter, SINGH, Mahavir, MASCAGNI, Paolo, POOLE, Stephen, ROBERTS, Michael, SHARP, Lindsay, HENDERSON, Brian

“…Much attention has focused on the Mycobacterium tuberculosis molecular chaperone chaperonin (Cpn) 60.2 (Hsp 65) in the pathology of tuberculosis because of its…”
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two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts by Winrow, Vivienne R, Mesher, Jon, Meghji, Sajeda, Morris, Christopher J, Maguire, Maria, Fox, Simon, Coates, Anthony R.M, Tormay, Peter, Blake, David R, Henderson, Brian

“…Mycobacterium tuberculosis produces two homologous chaperonin (Cpn)60 proteins, Cpn60.1 and Cpn60.2 (Hsp65). Both proteins stimulate human and murine monocyte…”
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Selenoprotein synthesis in E. coli by EHRENREICH, Armin, FORCHHAMMER, Karl, TORMAY, Peter, VEPREK, Barbara, BÖCK, August

“…The product of the selD gene from Escherichia coli catalyses the formation of an activated selenium compound which is required for the synthesis of Sec‐tRNA…”
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Comparative cell signalling activity of ultrapure recombinant chaperonin 60 proteins from prokaryotes and eukaryotes by Maguire, Maria, Poole, Stephen, Coates, Anthony R. M., Tormay, Peter, Wheeler‐Jones, Caroline, Henderson, Brian

“…Summary Heat‐shock protein (hsp)60/chaperonin 60 is a potent immunogen which has recently been claimed to have cell‐signalling actions upon myeloid and…”
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Barriers to heterologous expression of a selenoprotein gene in bacteria by Tormay, P, Böck, A

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rhizobium leguminosarum chaperonin 60.3, but not chaperonin 60.1, induces cytokine production by human monocytes: activity is dependent on interaction with cell surface CD14 by Lewthwaite, Jo, George, Roger, Lund, Peter A., Poole, Steve, Tormay, Peter, Sharp, Lindsay, Coates, Anthony R. M., Henderson, Brian

“…As part of a program of work to understand the interaction of bacterial chaperonins with human leukocytes, we have examined 2 of the 3 chaperonin 60 (Cpn 60)…”
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Bacterial selenocysteine synthase--structural and functional properties by Tormay, P, Wilting, R, Lottspeich, F, Mehta, P K, Christen, P, Böck, A

“…Selenocysteine synthase from Escherichia coli is a pyridoxal-5'-phosphate-containing enzyme which catalyses the conversion of seryl-tRNA(Sec) into…”
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Selenoprotein synthesis in E. coli. Purification and characterisation of the enzyme catalysing selenium activation by Ehrenreich, A, Forchhammer, K, Tormay, P, Veprek, B, Böck, A

“…The product of the selD gene from Escherichia coli catalyses the formation of an activated selenium compound which is required for the synthesis of Sec-tRNA…”
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Domain structure of the selenocysteine-specific translation factor SelB in prokaryotes by Böck, A, Hilgenfeld, R, Tormay, P, Wilting, R, Kromayer, M

“…Translation factor SelB is the key component for the specific decoding of UGA codons with selenocysteine at the ribosome. SelB binds selenocysteyl-tRNA(Sec),…”
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