Search Results - "TORHORST, J"

Patterns of HER-2/neu Amplification and Overexpression in Primary and Metastatic Breast Cancer by Simon, Ronald, Nocito, Antonio, Hübscher, Tanja, Bucher, Christoph, Torhorst, Joachim, Schraml, Peter, Bubendorf, Lukas, Mihatsch, Michael M., Moch, Holger, Wilber, Kim, Schötzau, Andreas, Kononen, Juha, Sauter, Guido

“…Background: Only 25% of patients with HER-2/neu-positive metastatic breast tumors respond favorably to trastuzamab (Herceptin) treatment. We hypothesized that…”
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Detecting Activation of Ribosomal Protein S6 Kinase by Complementary DNA and Tissue Microarray Analysis by Bärlund, Maarit, Forozan, Farahnaz, Kononen, Juha, Bubendorf, Lukas, Chen, Yidong, Bittner, Michael L., Torhorst, Joachim, Haas, Philippe, Bucher, Christoph, Sauter, Guido, Kallioniemi, Olli-P., Kallioniemi, Anne

“…Background: Studies by comparative genomic hybridization (CGH) have shown that chromosomal region 17q23 is amplified in up to 20% of primary breast cancers. We…”
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Multiple genes at 17q23 undergo amplification and overexpression in breast cancer by Bärlund, M, Monni, O, Kononen, J, Cornelison, R, Torhorst, J, Sauter, G, Kallioniemi OLLI-P, Kallioniemi, A

“…Studies by comparative genomic hybridization imply that amplification of the chromosomal region 17q22-q24 is common in breast cancer. Here, amplification and…”
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Long-term outcomes of breast cancer patients after endoscopic axillary lymph node dissection: a prospective analysis of 52 patients by LANGER, I, KOCHER, T, GULLER, U, TORHORST, J, OERTLI, D, HARDER, F, ZUBER, M

“…Reports on long-term outcomes after endoscopic axillary lymph node dissection (ALND) of breast cancer patients are still lacking in the medical literature. The…”
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Detection of new mutations in six out of 10 Swiss HNPCC families by genomic sequencing of the hMSH2 and hMLH1 genes by Buerstedde, J M, Alday, P, Torhorst, J, Weber, W, Müller, H, Scott, R

“…The cancer predisposition in most HNPCC families is believed to be associated with mutations in the human mismatch repair gene homologues hMSH2 and hMLH1. We…”
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Endoscopic surgery to the axilla--a substitute for conventional axillary clearance? by Harder, F, Zuber, M, Kocher, T, Torhorst, J

“…Nonpalpable, mammographically detected breast cancers are on the increase. The percentage of patients with histologically involved nodes is therefore…”
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Multiple primary cancers and estimation of the incidence rates and trends by Filali, K., Hédelin, G., Schaffer, P., Estève, J., Arveux, P., Bouchardy, C., Exbrayat, C., Faivre, J., Lévi, F., Macé-Lesech, J., Pottier, D., Torhorst, J.

“…The use of different registration rules from one registry to another, both generally and also for paired organs, leads to variations in the proportion of…”
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Quantitative determination of water- and lipid-soluble antioxidants in neoplastic and non-neoplastic human breast tissue by Langemann, H, Torhorst, J, Kabiersch, A, Krenger, W, Honegger, C G

“…Ascorbic acid, cysteine, glutathione and uric acid were determined by reverse-phase high-pressure liquid chromatography (HPLC) in 46 breast tissue samples…”
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The contribution of vascular obstruction to the functional defect that follows renal ischemia by Mason, June, Welsch, Johanna, Torhorst, Joachim

“…The contribution of vascular obstruction to the functional defect that follows renal ischemia. Experiments were performed on rats subjected to renal ischemia…”
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Role of the medullary perfusion defect in the pathogenesis of ischemic renal failure by Mason, June, Torhorst, Joachim, Welsch, Johanna

“…Role of the medullary perfusion defect in the pathogenesis of ischemic renal failure. Experiments were performed on rats to investigate the significance of the…”
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Prognostic relevance of gene amplifications and coamplifications in breast cancer by AL-KURAYA, Khawla, SCHRAML, Peter, ZUBER, Markus, DIETERICH, Holger, MROSS, Friedrich, WILBER, Kim, SIMON, Ronald, SAUTER, Guido, TORHORST, Joachim, TAPIA, Coya, ZAHARIEVA, Boriana, NOVOTNY, Hedvika, SPICHTIN, Hanspeter, MAURER, Robert, MIRLACHER, Martina, KÖCHLI, Ossi

“…Multiple different oncogenes have been described previously to be amplified in breast cancer including HER2, EGFR, MYC, CCND1, and MDM2. Gene amplification…”
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Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome by van de Rijn, Matt, Perou, Charles M., Tibshirani, Rob, Haas, Phillippe, Kallioniemi, Olli, Kononen, Juha, Torhorst, Joachim, Sauter, Guido, Zuber, Markus, Köchli, Ossi R., Mross, Frank, Dieterich, Holger, Seitz, Rob, Ross, Doug, Botstein, David, Brown, Pat

“…While several prognostic factors have been identified in breast carcinoma, the clinical outcome remains hard to predict for individual patients. Better…”
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Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma: A swiss experience with 588 tumors by MOCH, H, GASSER, T, AMIN, M. B, TORHORST, J, SAUTER, G, MIHATSCH, M. J

“…A new, internationally accepted histologic classification of renal cell carcinoma (RCC) and a new edition of the TNM staging system were introduced in 1997. In…”
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Metastatic patterns of renal carcinoma: an analysis of 687 necropsies by WEISS, L, HARLOS, J. P, COCHRANE, H. R, STOCK, D, WRIGHT, C, HORNE, C. H. W, TORHORST, J, GUNTHARD, B, HARTVEIT, F, SVENDSEN, E, HUANG, W.-L, GRUNDMANN, E, EDER, M, ZWICKNAGL, M

“…The metastatic behaviour of renal cell carcinoma has been studied in a series of 687 necropsies. The observations were consistent with the concept of…”
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Signal Transducer and Activator of Transcription-5 Activation and Breast Cancer Prognosis by Nevalainen, Marja T, Xie, Jianwu, Torhorst, Joachim, Bubendorf, Lukas, Haas, Philippe, Kononen, Juha, Sauter, Guido, Rui, Hallgeir

“…Transcription factor signal transducer and activator of transcription-5 (Stat5) promotes breast epithelial cell differentiation. We retrospectively analyzed…”
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Tissue Microarrays for Rapid Linking of Molecular Changes to Clinical Endpoints by Torhorst, Joachim, Bucher, Christoph, Kononen, Juha, Haas, Philippe, Zuber, Markus, Köchli, Ossi R., Mross, Frank, Dieterich, Holger, Moch, Holger, Mihatsch, Michael, Kallioniemi, Olli-P., Sauter, Guido

“…Advances in genomics and proteomics are dramatically increasing the need to evaluate large numbers of molecular targets for their diagnostic, predictive or…”
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Tissue microarrays for high-throughput molecular profiling of tumor specimens by Kononen, Juha, Bubendorf, Lukas, Kallionimeni, Anne, Bärlund, Maarit, Schraml, Peter, Leighton, Stephen, Torhorst, Joachim, Mihatsch, Michael J, Sauter, Guido, Kallionimeni, Olli-P

“…Many genes and signalling pathways controlling cell proliferation, death and differentiation, as well as genomic integrity, are involved in cancer development…”
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Patterns of HER-2/neu Amplification and Over-expression in Primary and Metastatic Breast Cancer by Simon, R, Nocito, A, Huebscher, T, Bucher, C, Torhorst, J, Schraml, P, Bubendorf, L, Mihatsch, M M, Moch, H, Wilber, K, Schoetzau, A, Kononen, J, Sauter, G

“…Only 25% of patients with HER-2/neu-positive metastatic breast tumors respond favorably to trastuzamab (Herceptin) treatment. We hypothesized that a high…”
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Health-care system, cancer registration and follow-up of cancer patients in Switzerland by Raymond, L, Torhorst, J

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Tissue microarrays for comparing molecular features with proliferation activity in breast cancer by Ruiz, Christian, Seibt, Silvia, Kuraya, Khawla Al, Siraj, Abdul K, Mirlacher, Martina, Schraml, Peter, Maurer, Robert, Spichtin, Hanspeter, Torhorst, Joachim, Popovska, Savelina, Simon, Ronald, Sauter, Guido

“…Tissue microarrays (TMAs) are potentially suited to find associations between molecular features and clinical outcome. Enhanced cell proliferation, as measured…”
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