Search Results - "TORGNER, I"
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Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum
Published in Neuroscience (01-02-1999)“…Phosphate activated glutaminase is a key enzyme in glutamate synthesis. Here we have employed a quantitative and high resolution immunogold procedure to…”
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Novel Form of Phosphate Activated Glutaminase in Cultured Astrocytes and Human Neuroblastoma Cells, PAG in Brain Pathology and Localization in the Mitochondria
Published in Neurochemical research (01-07-2008)“…A novel form of phosphate activated glutaminase (PAG), catalyzing the synthesis of glutamate from glutamine, has been detected in cultured astrocytes and…”
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Kinetics of a Novel Isoform of Phosphate Activated Glutaminase (PAG) in SH-SY5Y Neuroblastoma Cells
Published in Neurochemical research (01-06-2010)“…We have recently found that the neuroblastoma cell line SH-SY5Y expresses a novel form of phosphate activated glutaminase (PAG) which deamidates glutamine to…”
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Kinetics and localization of brain phosphate activated glutaminase
Published in Journal of neuroscience research (01-12-2001)“…The cellular concentration of phosphate, the main activator of phosphate activated glutaminase (PAG) is rather constant in brain and kidney. The enzyme…”
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Glutamine transport in brain mitochondria
Published in Neurochemistry international (01-08-2000)“…Gln is transported into rat brain synaptic and non-synaptic mitochondria by a protein catalyzed process. The uptake is significantly higher in synaptic than in…”
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Journal Article Conference Proceeding -
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Phosphate-activated glutaminase and mitochondrial glutamine transport in the brain
Published in Neurochemical research (01-10-2000)“…A review of the properties of purified and tissue bound phosphate activated glutaminase (PAG) in brain and kidney (pig and rat) is presented, based on kinetic,…”
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Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates
Published in Neurochemical research (01-07-1999)“…Glutamine transport into rat brain synaptic and non-synaptic mitochondria has been monitored by the uptake of [3H]glutamine and by mitochondrial swelling. The…”
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Conference Proceeding Journal Article -
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The orientation of phosphate activated glutaminase in the inner mitochondrial membrane of synaptic and non-synaptic rat brain mitochondria
Published in Neurochemistry international (1995)“…When rat brain synaptic and non-synaptic mitochondria were incubated with [ 14C]glutamine, [ 14C]glutamate was rapidly released to the incubation medium, and…”
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Glutamine transport in rat brain synaptic and non-synaptic mitochondria
Published in Neurochemical research (01-03-1999)“…Glutamine transport into rat brain mitochondria (synaptic and non-synaptic) was monitored by the uptake of [3H]glutamine as well as by mitochondrial swelling…”
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Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia
Published in Neurochemical research (01-04-1988)“…Phosphate activated glutaminase comprises two kinetically distinguishable enzyme forms in cultures of cerebellar granule cells, of cortical neurons and of…”
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Evidence indicating that pig renal phosphate-activated glutaminase has a functionally predominant external localization in the inner mitochondrial membrane
Published in The Journal of biological chemistry (15-07-1991)“…Phosphate-activated glutaminase in intact pig renal mitochondria was inhibited 50-70% by the sulfhydryl reagents mersalyl and N-ethylmaleimide (0.3-1.0 mM),…”
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Properties and submitochondrial localization of pig and rat renal phosphate-activated glutaminase
Published in American Journal of Physiology: Cell Physiology (01-09-2000)“…Two pools of phosphate-activated glutaminase (PAG) were separated from pig and rat renal mitochondria. The partition of enzyme activity corresponded with that…”
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An overview of mitochondrial glutamine transport and phosphate-activated glutaminase in the kidney
Published in Contributions to nephrology (01-01-1997)Get more information
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Properties of the pig renal mitochondrial glutamine transporter
Published in Contributions to nephrology (1994)Get more information
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Synthesis of transmitter glutamate and the glial-neuron interrelationship
Published in Molecular and chemical neuropathology (1990)“…Glutamate in glutamatergic neurons exists in a cytosolic pool, as well as a transmitter pool, which is assumed to be localized in synaptic vesicles…”
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Localization and function of glutamine synthetase and glutaminase
Published in Biochemical Society transactions (01-04-1987)Get more information
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Calcium stimulation of glutamine hydrolysis in synaptosomes from rat brain
Published in Neurochemical research (01-01-1983)“…Calcium stimulates the hydrolysis of glutamine in synaptosomes prepared from rat brain both by the sucrose- (12) and the Ficoll/sucrose-gradient techniques…”
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Interrelationship between glutamate and membrane-bound ATPases in nerve cells
Published in Molecular and chemical neuropathology (1990)“…Plasma membrane potential generated by Na+, K(+)-ATPase provides the driving force for high-affinity, Na(+)-dependent uptake of glutamate into the cytoplasm of…”
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