Search Results - "TOOI, Osamu"

Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver by Sato, Shoko, Shirakawa, Hitoshi, Tomita, Shuhei, Ohsaki, Yusuke, Haketa, Keiichi, Tooi, Osamu, Santo, Noriaki, Tohkin, Masahiro, Furukawa, Yuji, Gonzalez, Frank J., Komai, Michio

“…2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) is a common environmental contaminant. TCDD binds and activates the transcription factor aryl hydrocarbon receptor…”
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Thyroid Histopathology Assessments for the Amphibian Metamorphosis Assay to Detect Thyroid-active Substances by Grim, K. Christiana, Wolfe, Marilyn, Braunbeck, Thomas, Iguchi, Taisen, Ohta, Yasuhiko, Tooi, Osamu, Touart, Les, Wolf, Douglas C., Tietge, Joe

“…In support of an Organization for Economic Cooperation and Development (OECD) Amphibian Metamorphosis Assay (AMA) Test Guideline for the detection of…”
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Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid system-disrupting activities of environmental compounds by Opitz, Robert, Braunbeck, Thomas, Bogi, Christian, Pickford, Daniel B., Nentwig, Gerrit, Oehlmann, Jorg, Tooi, Osamu, Lutz, Ilka, Kloas, Werner

“…A eedi recognizedforthedevelopmentandevaluationofbioassaysfordetectionofthyroid s stem–disrupting compounds. The issue of testing for thyroid disruption can be…”
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Molecular cloning and characterization of ligand- and species-specificity of amphibian estrogen receptors by Katsu, Yoshinao, Taniguchi, Ena, Urushitani, Hiroshi, Miyagawa, Shinichi, Takase, Minoru, Kubokawa, Kaoru, Tooi, Osamu, Oka, Tomohiro, Santo, Noriaki, Myburgh, Jan, Matsuno, Akira, Iguchi, Taisen

“…Abstract Estrogens are essential for normal reproductive activity in both males and females as well as for ovarian differentiation during a critical…”
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Application of metamorphosis assay to a native Japanese amphibian species, Rana rugosa, for assessing effects of thyroid system affecting chemicals by Oka, Tomohiro, Miyahara, Maki, Yamamoto, Jun, Mitsui, Naoko, Fujii, Takaaki, Tooi, Osamu, Kashiwagi, Keiko, Takase, Minoru, Kashiwagi, Akihiko, Iguchi, Taisen

“…The aims of this study were to assess the utility of a metamorphosis assay for detecting thyroid hormone-disrupting chemicals using Rana rugosa, a domestic…”
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Molecular cloning of estrogen receptor alpha (ERα; ESR1) of the Japanese giant salamander, Andrias japonicus by Katsu, Yoshinao, Kohno, Satomi, Oka, Tomohiro, Mitsui, Naoko, Tooi, Osamu, Santo, Noriaki, Urushitani, Hiroshi, Fukumoto, Yukio, Kuwabara, Kazushi, Ashikaga, Kazuhide, Minami, Shinji, Kato, Shigeaki, Ohta, Yasuhiko, Guillette, Louis J., Iguchi, Taisen

“…Estrogens are essential for normal reproductive activity in females and males and for ovarian differentiation during a critical developmental stage in many…”
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Development of metamorphosis assay using Silurana tropicalis for the detection of thyroid system-disrupting chemicals by Mitsui, Naoko, Fujii, Takaaki, Miyahara, Maki, Oka, Tomohiro, Kashiwagi, Akihiko, Kashiwagi, Keiko, Hanada, Hideki, Urushitani, Hiroshi, Santo, Noriaki, Tooi, Osamu, Iguchi, Taisen

“…The West African clawed frog ( Silurana tropicalis), which resembles the South African clawed frog ( Xenopus laevis), but is somewhat smaller, has a diploid…”
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Estrogenic Activity of Phthalate Esters by In Vitro VTG Assay Using Primary-cultured Xenopus Hepatocytes by NOMURA, Yuji, MITSUI, Naoko, BHAWAL, Ujjal Kumar, SAWAJIRI, Masahiko, TOOI, Osamu, TAKAHASHI, Toru, OKAZAKI, Masayuki

“…Estrogenic activity of phthalate esters in dental soft resins was evaluated with an amphibian system consisting of a vitellogenin (VTG)-detecting Enzyme-Linked…”
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Suppression of Amphibian Metamorphosis by Bisphenol A and Related Chemical Substances by Goto, Yasushi, Kitamura, Shigeyuki, Kashiwagi, Keiko, Oofusa, Ken, Tooi, Osamu, Yoshizato, Katsutoshi, Sato, Jin, Ohta, Shigeru, Kashiwagi, Akihiko

“…This investigation attempts to clarify the effects of the plastic monomer bisphenol A (BPA) and related chemicals on 3,3′,5-triiodothyronine (T3)-induced and…”
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Detection of Legionella pneumophila serogroup 7 strain from bathwater samples in a Japanese hospital by Fujimura, Shigeru, Meguro, Miho, Chiba, Miyuki, Kawamura, Masato, Oka, Tomohiro, Tooi, Osamu, Maki, Fumi, Takeda, Hiroaki, Fujimura, Shigeru, Watanabe, Akira

“…Hospital-acquired legionellosis is one of the serious problems in nosocomial infection. For risk assessment of nosocomial Legionella infection, we surveyed…”
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Screening breeding sites of the common toad (Bufo bufo) in England and Wales for evidence of endocrine disrupting activity by Pickford, Daniel B., Jones, Alexandra, Velez-Pelez, Alejandra, Iguchi, Taisen, Mitsui, Naoko, Tooi, Osamu

“…Anuran amphibians are often present in agricultural landscapes and may therefore be exposed to chemicals in surface waters used for breeding. We used passive…”
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Corrigendum to “Screening breeding sites of the common toad (Bufo bufo) in England and Wales for evidence of endocrine disrupting activity” [Ecotoxicol. Environ. Saf. 117 (2015) 7–19] by Pickford, Daniel B., Jones, Alexandra, Velez-Pelez, Alejandra, Orton, Frances, Iguchi, Taisen, Mitsui, Naoko, Tooi, Osamu

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Vitellogenin-inducing activities of natural, synthetic, and environmental estrogens in primary cultured Xenopus laevis hepatocytes by Mitsui, Naoko, Tooi, Osamu, Kawahara, Akira

“…Vitellogenin (VTG)-inducing activities of natural estrogens (E1: estrone, E2:17β-estradiol, E3: estriol, α-E2: 17α-estradiol), synthetic estrogens (EE2:…”
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Effect of atrazine on metamorphosis and sexual differentiation in Xenopus laevis by Oka, Tomohiro, Tooi, Osamu, Mitsui, Naoko, Miyahara, Maki, Ohnishi, Yuta, Takase, Minoru, Kashiwagi, Akihiko, Shinkai, Tadashi, Santo, Noriaki, Iguchi, Taisen

“…There is a growing international concern that commonly used environmental contaminants have the potential to disrupt the development and functioning of the…”
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Effects of an androgenic growth promoter 17β-trenbolone on masculinization of Mosquitofish ( Gambusia affinis affinis) by Sone, Kiyoaki, Hinago, Megumi, Itamoto, Misaki, Katsu, Yoshinao, Watanabe, Hajime, Urushitani, Hiroshi, Tooi, Osamu, Guillette, Louis J., Iguchi, Taisen

“…Endocrine disrupting chemicals can affect normal hormone dependent processes through numerous mechanisms, including ligand mimicky. 17β-Trenbolone (TB), a…”
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Sandwich ELISAs for quantification of Xenopus laevis vitellogenin and albumin and their application to measurement of estradiol-17β effects on whole animals and primary-cultured hepatocytes by Mitsui, Naoko, Tooi, Osamu, Kawahara, Akira

“…Sandwich enzyme-linked immunosorbent assay (ELISA) was developed for quantification of vitellogenin (VTG) and albumin (ALB) in Xenopus laevis. Working ranges…”
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All ZZ male Xenopus laevis provides a clear sex-reversal test for feminizing endocrine disruptors by Oka, Tomohiro, Mitsui, Naoko, Hinago, Megumi, Miyahara, Maki, Fujii, Takaaki, Tooi, Osamu, Santo, Noriaki, Urushitani, Hiroshi, Iguchi, Taisen, Hanaoka, Yoichi, Mikami, Hirokazu

“…We investigated the possibility of using all ZZ male Xenopus laevis tadpoles produced by mating normal ZZ males with feminized ZZ males to detect estrogenic…”
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Expression of thyroid hormone receptor βA gene assayed by transgenic Xenopus laevis carrying its promoter sequences by Oofusa, Ken, Tooi, Osamu, Kashiwagi, Akihiko, Kashiwagi, Keiko, Kondo, Yasuyuki, Watanabe, Yusuke, Sawada, Takuya, Fujikawa, Kazuyuki, Yoshizato, Katsutoshi

“…The responsiveness of thyroid hormone responsive element (TRE)-containing promoter sequence to thyroid hormone (TH) was studied utilizing Xenopus laevis…”
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Effects of an androgenic growth promoter 17beta-trenbolone on masculinization of Mosquitofish (Gambusia affinis affinis) by Sone, Kiyoaki, Hinago, Megumi, Itamoto, Misaki, Katsu, Yoshinao, Watanabe, Hajime, Urushitani, Hiroshi, Tooi, Osamu, Guillette, Jr, Louis J, Iguchi, Taisen

“…Endocrine disrupting chemicals can affect normal hormone dependent processes through numerous mechanisms, including ligand mimicky. 17beta-Trenbolone (TB), a…”
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Availability of in vitro vitellogenin assay for screening of estrogenic and anti-estrogenic activities of environmental chemicals by Iguchi, Taisen, Irie, Fumi, Urushitani, Hiroshi, Tooi, Osamu, Kawashima, Yukio, Roberts, Mike, Norrgren, Leif, Hutchinson, Thomas

“…Vitellogenin (VTG) protein, VTG mRNA, other egg yolk proteins, vitelline envelope proteins and their mRNAs are produced in the liver of oviparous species by…”
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