Search Results - "TONG, Leah"

Cobicistat Boosts the Intestinal Absorption of Transport Substrates, Including HIV Protease Inhibitors and GS-7340, In Vitro by LEPIST, Eve-Irene, PHAN, Truc K, ROY, Anupma, TONG, Leah, MACLENNAN, Kelly, MURRAY, Bernard, RAY, Adrian S

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Mechanism of Active Renal Tubular Efflux of Tenofovir by RAY, Adrian S, CIHLAR, Tomas, ROBINSON, Kelly L, TONG, Leah, VELA, Jennifer E, FULLER, Michael D, WIEMAN, Lani M, EISENBERG, Eugene J, RHODES, Gerry R

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Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas by Ordonez, Alvaro A, Pokkali, Supriya, Kim, Sunhwa, Carr, Brian, Klunk, Mariah H, Tong, Leah, Saini, Vikram, Chang, Yong S, McKevitt, Matthew, Smith, Victoria, Gossage, David L, Jain, Sanjay K

“…Matrix metalloproteinase (MMP)-9 is a zinc-dependent protease associated with early immune responses to Mycobacterium tuberculosis infection, macrophage…”
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Effects of Human Immunodeficiency Virus Protease Inhibitors on the Intestinal Absorption of Tenofovir Disoproxil Fumarate In Vitro by TONG, Leah, PHAN, Truc K, ROBINSON, Kelly L, BABUSIS, Darius, STRAB, Robert, BHOOPATHY, Siddhartha, HIDALGO, Ismael J, RHODES, Gerald R, RAY, Adrian S

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Combination Therapy of Selective MMP9 Inhibitor and JAK Inhibitor Is Effective to Induce Disease Control in Mouse DSS Model of Colitis: 593 by Kim, Sunhwa, Carr, Brian, Tong, Leah, Sobczyk, Monika, Zheng, Jim, Lu, Bing, Mikaelian, Igor, Brockett, Robert, Jin, Debi, Wang, Ruth, Kanwar, Bittoo, Smith, Victoria

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Synthesis and biological evaluation of phosphonate analogues of nevirapine by Parrish, Jay, Tong, Leah, Wang, Michael, Chen, Xiaowu, Lansdon, Eric B., Cannizzaro, Carina, Zheng, Xubin, Desai, Manoj C., Xu, Lianhong

“…A series of nevirapine-based analogues containing the phosphonate functionality were prepared and evaluated in vitro against HIV RT. A series of…”
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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350) by Xu, Lianhong, Liu, Hongtao, Hong, Allen, Vivian, Randy, Murray, Bernard P., Callebaut, Christian, Choi, You-Chul, Lee, Melody S., Chau, Jennifer, Tsai, Luong K., Stray, Kirsten M., Strickley, Robert G., Wang, Jianhong, Tong, Leah, Swaminathan, Swami, Rhodes, Gerry R., Desai, Manoj C.

“…A series of novel 1,4-diamine-based CYP3A inhibitors were designed and evaluated. A potent and selective inhibitor of CYP3A, cobicistat (35, GS-9350) was…”
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Molecular assessment of the potential for renal drug interactions between tenofovir and HIV protease inhibitors by CIHLAR, Tomas, RAY, Adrian S, LAFLAMME, Genevieve, VELA, Jennifer E, TONG, Leah, FULLER, Michael D, ROY, Anupma, RHODES, Gerald R

“…Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion transporters 1 and 3 (hOAT1 and hOAT3) coupled with…”
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Expression and characterization of soluble human parainfluenza virus type 1 hemagglutinin–neuraminidase glycoprotein by Wang, Z.Michael, Tong, L.Leah, Grant, Deborah, Cihlar, Tomas

“…Human parainfluenza virus types 1 (hPIV-1), 2, and 3 represent significant respiratory pathogens for which no antiviral treatment is currently available. To…”
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