Search Results - "TOMASONI, Susanna"

Editorial: Women in renal pharmacology: 2021 by Benigni, Ariela, Tomasoni, Susanna

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Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells by Ciampi, Osele, Bonandrini, Barbara, Derosas, Manuela, Conti, Sara, Rizzo, Paola, Benedetti, Valentina, Figliuzzi, Marina, Remuzzi, Andrea, Benigni, Ariela, Remuzzi, Giuseppe, Tomasoni, Susanna

“…Generating new kidneys using tissue engineering technologies is an innovative strategy for overcoming the shortage of donor organs for transplantation. Here we…”
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Imaging the Kidney with an Unconventional Scanning Electron Microscopy Technique: Analysis of the Subpodocyte Space in Diabetic Mice by Conti, Sara, Remuzzi, Giuseppe, Benigni, Ariela, Tomasoni, Susanna

“…Transmission electron microscopy (TEM) remains the gold standard for renal histopathological diagnoses, given its higher resolving power, compared with light…”
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Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells by Tomasoni, Susanna, Longaretti, Lorena, Rota, Cinzia, Morigi, Marina, Conti, Sara, Gotti, Elisa, Capelli, Chiara, Introna, Martino, Remuzzi, Giuseppe, Benigni, Ariela

“…Bone marrow-mesenchymal stem cells (BM-MSC) ameliorate renal dysfunction and repair tubular damage of acute kidney injury by locally releasing growth factors,…”
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Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis by Perico, Luca, Morigi, Marina, Pezzotta, Anna, Corna, Daniela, Brizi, Valerio, Conti, Sara, Zanchi, Cristina, Sangalli, Fabio, Trionfini, Piera, Buttò, Sara, Xinaris, Christodoulos, Tomasoni, Susanna, Zoja, Carlamaria, Remuzzi, Giuseppe, Benigni, Ariela, Imberti, Barbara

“…Abnormal kidney development leads to lower nephron number, predisposing to renal diseases in adulthood. In embryonic kidneys, nephron endowment is dictated by…”
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Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor by Zanchi, Cristina, Locatelli, Monica, Benigni, Ariela, Corna, Daniela, Tomasoni, Susanna, Rottoli, Daniela, Gaspari, Flavio, Remuzzi, Giuseppe, Zoja, Carlamaria

“…Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone mainly produced by bone that acts in the kidney through FGF receptors and Klotho. Here we…”
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COVID-19 and lombardy: TESTing the impact of the first wave of the pandemic by Perico, Luca, Tomasoni, Susanna, Peracchi, Tobia, Perna, Annalisa, Pezzotta, Anna, Remuzzi, Giuseppe, Benigni, Ariela

“…Italy was the first western country to experience a large Coronavirus Disease 2019 (COVID-19) outbreak and the province of Bergamo experienced one of the…”
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MYO1E Mutations and Childhood Familial Focal Segmental Glomerulosclerosis by Mele, Caterina, Iatropoulos, Paraskevas, Donadelli, Roberta, Calabria, Andrea, Maranta, Ramona, Cassis, Paola, Buelli, Simona, Tomasoni, Susanna, Piras, Rossella, Krendel, Mira, Bettoni, Serena, Morigi, Marina, Delledonne, Massimo, Pecoraro, Carmine, Abbate, Isabella, Capobianchi, Maria Rosaria, Hildebrandt, Friedhelm, Otto, Edgar, Schaefer, Franz, Macciardi, Fabio, Ozaltin, Fatih, Emre, Sevinc, Ibsirlioglu, Tulin, Benigni, Ariela, Remuzzi, Giuseppe, Noris, Marina

“…Focal segmental glomerulosclerosis (FSGS) affects the podocytes. The molecular cause of over half the cases is unknown, and treatment is elusive. This study…”
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Generation of a homozygous CIITA knockout iPS cell line using the CRISPR-Cas9 system by Romano, Elena, Trionfini, Piera, Giampietro, Roberta, Benigni, Ariela, Tomasoni, Susanna

“…Human induced pluripotent stem cells (iPSCs) have great promise in regenerative medicine. However, several limitations, including immune-incompatibility, have…”
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Endothelial Glycocalyx of Peritubular Capillaries in Experimental Diabetic Nephropathy: A Target of ACE Inhibitor-Induced Kidney Microvascular Protection by Locatelli, Monica, Rottoli, Daniela, Mahmoud, Rayan, Abbate, Mauro, Corna, Daniela, Cerullo, Domenico, Tomasoni, Susanna, Remuzzi, Giuseppe, Zoja, Carlamaria, Benigni, Ariela, Macconi, Daniela

“…Peritubular capillary rarefaction is a recurrent aspect of progressive nephropathies. We previously found that peritubular capillary density was reduced in…”
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Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury by Imberti, Barbara, Tomasoni, Susanna, Ciampi, Osele, Pezzotta, Anna, Derosas, Manuela, Xinaris, Christodoulos, Rizzo, Paola, Papadimou, Evangelia, Novelli, Rubina, Benigni, Ariela, Remuzzi, Giuseppe, Morigi, Marina

“…Acute kidney injury (AKI) is one of the most relevant health issues, leading to millions of deaths. The magnitude of the phenomenon remarks the urgent need for…”
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Long-term adaptive response in COVID-19 vaccine recipients and the effect of a booster dose by Perico, Luca, Todeschini, Marta, Casiraghi, Federica, Mister, Marilena, Pezzotta, Anna, Peracchi, Tobia, Tomasoni, Susanna, Trionfini, Piera, Benigni, Ariela, Remuzzi, Giuseppe

“…We examined the immune response in subjects previously infected with SARS-CoV2 and infection-naïve 9 months after primary 2-dose COVID-19 mRNA vaccination and…”
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Insulin-like growth factor-1 sustains stem cell-mediated renal repair by IMBERTI, Barbara, MORIGI, Marina, ABBATE, Mauro, ZOJA, Carla, REMUZZI, Giuseppe, TOMASONI, Susanna, ROTA, Cinzia, CORNA, Daniela, LONGARETTI, Lorena, ROTTOLI, Daniela, VALSECCHI, Federica, BENIGNI, Ariela, JUN WANG

“…In mice with cisplatin-induced acute kidney injury, administration of bone marrow-derived mesenchymal stem cells (MSC) restores renal tubular structure and…”
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Functional Human Podocytes Generated in Organoids from Amniotic Fluid Stem Cells by Xinaris, Christodoulos, Benedetti, Valentina, Novelli, Rubina, Abbate, Mauro, Rizzo, Paola, Conti, Sara, Tomasoni, Susanna, Corna, Daniela, Pozzobon, Michela, Cavallotti, Daniela, Yokoo, Takashi, Morigi, Marina, Benigni, Ariela, Remuzzi, Giuseppe

“…Generating kidney organoids using human stem cells could offer promising prospects for research and therapeutic purposes. However, no cell-based strategy has…”
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Hypoimmunogenic Human Pluripotent Stem Cells as a Powerful Tool for Liver Regenerative Medicine by Trionfini, Piera, Romano, Elena, Varinelli, Marco, Longaretti, Lorena, Rizzo, Paola, Giampietro, Roberta, Caroli, Annalina, Aiello, Sistiana, Todeschini, Marta, Casiraghi, Federica, Remuzzi, Giuseppe, Benigni, Ariela, Tomasoni, Susanna

“…Induced pluripotent stem cells (iPSC) have huge potential as cell therapy for various diseases, given their potential for unlimited self-renewal and capability…”
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Generation of PKD1 mono-allelic and bi-allelic knockout iPS cell lines using CRISPR-Cas9 system by Romano, Elena, Trionfini, Piera, Ciampi, Osele, Benigni, Ariela, Tomasoni, Susanna

“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease, characterised by the development of multiple fluid-filled…”
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Generation of two isogenic knockout PKD2 iPS cell lines, IRFMNi003-A-1 and IRFMNi003-A-2, using CRISPR/Cas9 technology by Trionfini, Piera, Ciampi, Osele, Romano, Elena, Benigni, Ariela, Tomasoni, Susanna

“…Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent inherited renal disease, characterized by multiple cysts that can lead to kidney…”
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Generation of functional podocytes from human induced pluripotent stem cells by Ciampi, Osele, Iacone, Roberto, Longaretti, Lorena, Benedetti, Valentina, Graf, Martin, Magnone, Maria Chiara, Patsch, Christoph, Xinaris, Christodoulos, Remuzzi, Giuseppe, Benigni, Ariela, Tomasoni, Susanna

“…Generating human podocytes in vitro could offer a unique opportunity to study human diseases. Here, we describe a simple and efficient protocol for obtaining…”
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Generation of two isogenic iPS cell lines (IRFMNi002-A and IRFMNi002-B) from a patient affected by Focal Segmental Glomerulosclerosis carrying a heterozygous c.565G>A mutation in PAX2 gene by Ciampi, Osele, Romano, Elena, Benigni, Ariela, Tomasoni, Susanna

“…Focal Segmental Glomerulosclerosis (FSGS) is the typical renal histologic lesion in familial steroid-resistant nephrotic syndrome, for which there is currently…”
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Shiga Toxin Promotes Podocyte Injury in Experimental Hemolytic Uremic Syndrome via Activation of the Alternative Pathway of Complement by LOCATELLI, Monica, BUELLI, Simona, REMUZZI, Giuseppe, ZOJA, Carlamaria, MORIGI, Marina, PEZZOTTA, Anna, CORNA, Daniela, PERICO, Luca, TOMASONI, Susanna, ROTTOLI, Daniela, RIZZO, Paola, CONTI, Debora, THURMAN, Joshua M

“…Shiga toxin (Stx)-producing Escherichia coli is the offending agent of postdiarrhea-associated hemolytic uremic syndrome (HUS), a disorder of glomerular…”
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