Search Results - "TOKUDA, Harukuni"

Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo by Iranshahi, Mehrdad, Sahebkar, Amirhossein, Takasaki, Midori, Konoshima, Takao, Tokuda, Harukuni

“…Umbelliprenin is a prenylated compound, which belongs to the class of sesquiterpene coumarins. In continuation of our earlier in-vitro finding, we determined…”
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Identification of novel sesquiterpene synthase genes that mediate the biosynthesis of valerianol, which was an unknown ingredient of tea by Hattan, Jun-ichiro, Shindo, Kazutoshi, Sasaki, Tetsuya, Ohno, Fumina, Tokuda, Harukuni, Ishikawa, Kazuhiko, Misawa, Norihiko

“…Seven cDNA clones encoding terpene synthases (TPSs), their structures closely related to each other, were isolated from the flower of Camellia hiemalis…”
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Structural optimization of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, as an anticancer lead by Kikumori, Masayuki, Yanagita, Ryo C., Tokuda, Harukuni, Suenaga, Kiyotake, Nagai, Hiroshi, Irie, Kazuhiro

“…Aplog-1 is a simplified analog of debromoaplysiatoxin (DAT) with potent tumor-promoting and proinflammatory activities. Aplog-1 and DAT exhibited…”
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Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines by Kapadia, Govind J, Azuine, Magnus A, Rao, G Subba, Arai, Takanari, Iida, Akira, Tokuda, Harukuni

“…Previous cancer chemoprevention studies from our laboratories and by other investigators have demonstrated that the extract of red beetroot (Beta vulgaris L.),…”
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Anti-inflammatory and Antitumor-Promoting Effects of the Triterpene Acids from the Leaves of Eriobotrya japonica by Banno, Norihiro, Akihisa, Toshihiro, Tokuda, Harukuni, Yasukawa, Ken, Taguchi, Yosuke, Akazawa, Hiroyuki, Ukiya, Motohiko, Kimura, Yumiko, Suzuki, Takashi, Nishino, Hoyoku

“…Sixteen triterpene acids, viz., five of the oleanane-type (1—5), nine of the ursane-type (6—14), and two of the lupane-type (15, 16), were isolated and…”
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Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri by Banno, Norihiro, Akihisa, Toshihiro, Yasukawa, Ken, Tokuda, Harukuni, Tabata, Keiichi, Nakamura, Yuji, Nishimura, Reiko, Kimura, Yumiko, Suzuki, Takashi

“…Boswellic acids are the main well-known active components of the resin of Boswellia carteri (Burseraceae) and these are still dealing with the ethnomedicinal…”
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Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae by Yamashita, Mitsuaki, Kaneko, Masafumi, Tokuda, Harukuni, Nishimura, Katsumi, Kumeda, Yuko, Iida, Akira

“…Four chiral naphtho[2,3- b]furan-4,9-diones including 1 and 2 found in the inner bark of Tabebuia avellanedae were synthesized and their biological activities…”
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Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects by Banno, N. (Ichimura Pharcos Co. Ltd., Shinsei, Gifu (Japan)), Akihisa, T, Tokuda, H, Yasukawa, K, Higashihara, H, Ukita, M, Watanabe, K, Kimura, Y, Hawegara, J, Nishio, H

“…Nine triterpene acids, viz., six of the ursane type, ursolic acid (1), corosolic acid (2), 3-epicorosolic acid (3), pomolic acid (4), tormentic acid (5) and…”
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Concise Synthesis of Heterocycle-Fused Naphthoquinones by Employing Sonogashira Coupling and Tandem Addition-Elimination/Intramolecular Cyclization by Ueda, Kazunori, Yamashita, Mitsuaki, Sakaguchi, Koichi, Tokuda, Harukuni, Iida, Akira

“…A concise method for the synthesis of heterocycle-fused naphthoquinones such as naphtho[2,3-b]-furan-4,9-dione, 1H-benz[f]indole-4,9-dione, and…”
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Anti-Inflammatory, Anti-Tumor-Promoting, and Cytotoxic Activities of Constituents of Marigold (Calendula officinalis) Flowers by Ukiya, Motohiko, Akihisa, Toshihiro, Yasukawa, Ken, Tokuda, Harukuni, Suzuki, Takashi, Kimura, Yumiko

“…Ten oleanane-type triterpene glycosides, 1−10, including four new compounds, calendulaglycoside A 6‘-O-methyl ester (2), calendulaglycoside A 6‘-O-n-butyl…”
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4-Ketozeinoxanthin, a novel carotenoid produced in Escherichia coli through metabolic engineering using carotenogenic genes of bacterium and liverwort by Maoka, Takashi, Takemura, Miho, Tokuda, Harukuni, Suzuki, Nobutaka, Misawa, Norihiko

“…[Display omitted] In order to produce a novel keto-carotenoid in Escherichia coli, we introduced the marine bacterial carotenoid ketolase gene (crtW) into…”
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Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin by Maoka, Takashi, Yasui, Hiroyuki, Ohmori, Aya, Tokuda, Harukuni, Suzuki, Nobutaka, Osawa, Ayako, Shindo, Kazutoshi, Ishibashi, Takashi

“…Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin, which are biosynthetic intermediates from β-carotene to…”
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Chemoprevention of skin cancer: effect of Lawsonia inermis L. (Henna) leaf powder and its pigment artifact, lawsone in the Epstein- Barr virus early antigen activation assay and in two-stage mouse skin carcinogenesis models by Kapadia, Govind J, Rao, G Subba, Sridhar, Rajagopalan, Ichiishi, Eiichiro, Takasaki, Midori, Suzuki, Nobutaka, Konoshima, Takao, Iida, Akira, Tokuda, Harukuni

“…In continuation of our studies with chemoprevention potential of plant-derived naphthoquinone derivatives, leaf powder of the medicinal plant Lawsonia inermis…”
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Anti-Inflammatory and Anti-Tumor-Promoting Effects of Triterpene Acids and Sterols from the Fungus Ganoderma lucidum by Akihisa, Toshihiro, Nakamura, Yuji, Tagata, Masaaki, Tokuda, Harukuni, Yasukawa, Ken, Uchiyama, Emiko, Suzuki, Takashi, Kimura, Yumiko

“…A series of lanostane‐type triterpene acids, including eleven lucidenic acids (3, 4, 9, 10, 13–19) and six ganoderic acids (20–22, 24, 26, 27), as well as six…”
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Total Synthesis and in Vitro Anti-Tumor-Promoting Activities of Racemic Acetophenone Monomers from Acronychia trifoliolata by Morita, Chihiro, Kobayashi, Yukiko, Saito, Yohei, Miyake, Katsunori, Tokuda, Harukuni, Suzuki, Nobutaka, Ichiishi, Eiichiro, Lee, Kuo-Hsiung, Nakagawa-Goto, Kyoko

“…Six acetophenone derivatives, acronyculatins I (1), J (2), K (3), L (4), N (5), and O (6), were recently isolated from Acronychia trifoliolata, and the…”
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Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus by Nakata, Tomoko, Yamada, Takeshi, Taji, Sayaka, Ohishi, Hirofumi, Wada, Shun-ichi, Tokuda, Harukuni, Sakuma, Kazuo, Tanaka, Reiko

“…Two new lanostane-type triterpenoids, inonotsuoxide, A ( 1) and B ( 2), were isolated from the sclerotia of Inonotus obliquus. Their structures were determined…”
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Cytotoxic and Nitric Oxide Production-Inhibitory Activities of Limonoids and Other Compounds from the Leaves and Bark of Melia azedarach by Pan, Xin, Matsumoto, Masahiro, Nishimoto, Yuki, Ogihara, Eri, Zhang, Jie, Ukiya, Motohiko, Tokuda, Harukuni, Koike, Kazuo, Akihisa, Momoko, Akihisa, Toshihiro

“…Nine limonoids, 1–9, one apocarotenoid, 11, one alkaloid, 12, and one steroid, 13, from the leaf extract; and one triterpenoid, 10, five steroids, 14–18, and…”
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Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity by Taji, Sayaka, Yamada, Takeshi, Wada, Shun-ichi, Tokuda, Harukuni, Sakuma, Kazuo, Tanaka, Reiko

“…Two new lanostane-type triterpenoids, 1 and 2 besides two known lanostane-type triterpenoids, 3 and 4 were isolated from the sclerotia of Inonotus obliquus…”
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Evaluation of Flavoglaucin, Its Derivatives and Pyranonigrins Produced by Molds Used in Fermented Foods for Inhibiting Tumor Promotion by MIYAKE, Yoshiaki, ITO, Chihiro, TOKUDA, Harukuni, OSAWA, Toshihiko, ITOIGAWA, Masataka

“…Flavoglaucin, its derivatives, and pyranonigrins, which are antioxidants produced by the molds used in fermented foods, were examined for their inhibition of…”
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Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor by Galal, Shadia A., Abdelsamie, Ahmed S., Soliman, Salwa M., Mortier, Jeremie, Wolber, Gerhard, Ali, Mamdouh M., Tokuda, Harukuni, Suzuki, Nobutaka, Lida, Akira, Ramadan, Raghda A., El Diwani, Hoda I.

“…The cancer chemopreventive activity of quinoxaline derivatives 1–20 has been evaluated by studying the inhibitory effect on Epstein–Barr virus early antigen…”
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