Search Results - "TODA, Masaaki"
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Increased expression of Protein S in eyes with diabetic retinopathy and diabetic macular edema
Published in Scientific reports (17-05-2021)“…Protein S (PS) is a multifunctional glycoprotein that ameliorates the detrimental effects of diabetes mellitus (DM). The aim of this study was to evaluate the…”
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2
Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis
Published in Scientific reports (15-10-2021)“…Crb2 is a cell polarity-related type I transmembrane protein expressed in the apical membrane of podocytes. Knockdown of crb2 causes glomerular permeability…”
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3
Inhibition of a Microbiota-Derived Peptide Ameliorates Established Acute Lung Injury
Published in The American journal of pathology (01-06-2023)“…Acute lung injury (ALI) is a clinical syndrome characterized by a diffuse lung inflammation that commonly evolves into acute respiratory distress syndrome and…”
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4
Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression
Published in International journal of molecular sciences (01-04-2023)“…Idiopathic pulmonary fibrosis is a progressive and fatal disease with a poor prognosis. Matrix metalloproteinase-2 is involved in the pathogenesis of organ…”
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5
Axl and immune checkpoints inhibitors from fruiting bodies of Pleurocybella porrigens
Published in Journal of antibiotics (01-10-2020)“…A novel compound ( 1 ) and three known ones ( 2 − 4 ) were isolated from the fruiting bodies of Pleurocybella porrigens . The structure of the novel compound…”
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6
Culture Conditions for Mycelial Growth and Anti-Cancer Properties of Termitomyces
Published in Mycobiology (04-03-2023)“…Termitomyces sp. that grow in symbiosis with fungus-farming Termites have medicinal properties. However, they are rare in nature, and their artificial culture…”
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7
Axl, Immune Checkpoint Molecules and HIF Inhibitors from the Culture Broth of Lepista luscina
Published in Molecules (Basel, Switzerland) (15-12-2022)“…Two compounds and were isolated from the culture broth of . This is the first time that compound was isolated from a natural source. The structure of compound…”
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Transforming Growth Factorβ1 Overexpression Is Associated with Insulin Resistance and Rapidly Progressive Kidney Fibrosis under Diabetic Conditions
Published in International journal of molecular sciences (17-11-2022)“…Diabetes mellitus is a global health problem. Diabetic nephropathy is a common complication of diabetes mellitus and the leading cause of end-stage renal…”
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9
Inhibition of Cell Apoptosis and Amelioration of Pulmonary Fibrosis by Thrombomodulin
Published in The American journal of pathology (01-10-2017)“…Pulmonary fibrosis is the terminal stage of a group of idiopathic interstitial pneumonias, of which idiopathic pulmonary fibrosis is the most frequent and…”
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10
The Protective Role of KANK1 in Podocyte Injury
Published in International journal of molecular sciences (01-06-2024)“…Approximately 30% of steroid-resistant nephrotic syndromes are attributed to monogenic disorders that involve 27 genes. Mutations in family members have also…”
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Novel Cyclopropyl Compounds, Cyclopropylvirgines A to G, from the Fruiting Bodies of Amanita Virgineoides
Published in Bulletin of the Chemical Society of Japan (15-06-2023)“…Seven novel compounds (1–7) along with four known compounds (8–11) were isolated from the fruiting bodies of Amanita virgineoides. The structures of 1–7 were…”
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12
Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
Published in Frontiers in immunology (20-09-2018)“…Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast…”
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Protein S is Protective in Acute Lung Injury by Inhibiting Cell Apoptosis
Published in International journal of molecular sciences (02-03-2019)“…Acute lung injury is a fatal disease characterized by inflammatory cell infiltration, alveolar-capillary barrier disruption, protein-rich edema, and impairment…”
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14
Helicobacter pylori infection: is there circulating vacuolating cytotoxin A or cytotoxin-associated gene A protein?
Published in Gut pathogens (03-12-2022)“…Abstract Background Helicobacter pylori infection is a well-recognized cause of gastric diseases, including chronic gastritis, peptic ulcer, and gastric…”
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Mice overexpressing latent matrix metalloproteinase-2 develop lung emphysema after short-term exposure to cigarette smoke extract
Published in Biochemical and biophysical research communications (26-02-2018)“…Chronic obstructive pulmonary disease is the major growing cause of mortality and morbidity worldwide, and it is going to become the third most common cause of…”
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16
Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma
Published in Frontiers in immunology (02-08-2019)“…Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated…”
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Degradation Products of Complex Arabinoxylans by Bacteroides intestinalis Enhance the Host Immune Response
Published in Microorganisms (Basel) (22-05-2021)“…Bacteroides spp. of the human colonic microbiome degrade complex arabinoxylans from dietary fiber and release ferulic acid. Several studies have demonstrated…”
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Anti-apoptotic activity of human matrix metalloproteinase-2 attenuates diabetes mellitus
Published in Metabolism, clinical and experimental (01-05-2018)“…Chronic progression of diabetes is associated with decreased pancreatic islet mass due to apoptosis of β-cells. Patients with diabetes have increased…”
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Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells
Published in PloS one (21-05-2013)“…Eosinophilic inflammation and remodeling of the airways including subepithelial fibrosis and myofibroblast hyperplasia are characteristic pathological findings…”
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20
Low dose of alcohol attenuates pro-atherosclerotic activity of thrombin
Published in Atherosclerosis (01-10-2017)“…Thrombin, the active enzyme of the coagulation system, plays a critical role in the pathogenesis of atherosclerosis. Vascular repair promoted by stromal…”
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