Search Results - "TOBE, K"

Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice by Fujisaka, S., Usui, I., Ikutani, M., Aminuddin, A., Takikawa, A., Tsuneyama, K., Mahmood, A., Goda, N., Nagai, Y., Takatsu, K., Tobe, K.

“…Aims/hypothesis As obesity progresses, adipose tissue exhibits a hypoxic and inflammatory phenotype characterised by the infiltration of adipose tissue…”
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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects by Kadowaki, Takashi, Yamauchi, Toshimasa, Kamon, Junji, Ito, Yusuke, Tsuchida, Atsushi, Yokomizo, Takehiko, Kita, Shunbun, Sugiyama, Takuya, Miyagishi, Makoto, Hara, Kazuo, Tsunoda, Masaki, Murakami, Koji, Ohteki, Toshiaki, Uchida, Shoko, Takekawa, Sato, Waki, Hironori, Tsuno, Nelson H, Shibata, Yoichi, Terauchi, Yasuo, Froguel, Philippe, Tobe, Kazuyuki, Koyasu, Shigeo, Taira, Kazunari, Kitamura, Toshio, Shimizu, Takao, Nagai, Ryozo

“…Adiponectin (also known as 30-kDa adipocyte complement-related protein; Acrp30) is a hormone secreted by adipocytes that acts as an antidiabetic and…”
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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity by Kadowaki, T, Yamauchi, T, Kamon, J, Waki, H, Terauchi, Y, Kubota, N, Hara, K, Mori, Y, Ide, T, Murakami, K, Tsuboyama-Kasaoka, N, Ezaki, O, Akanuma, Y, Gavrilova, O, Vinson, C, Reitman, M.L, Kagechika, H, Shudo, K, Yoda, M, Nakano, Y, Tobe, K, Nagai, R, Kimura, S, Tomita, M, Froguel, P

“…Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a susceptibility locus for type 2 diabetes and metabolic syndrome to…”
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Lepton-flavor violation via right-handed neutrino Yukawa couplings in the supersymmetric standard model by Hisano, J, Moroi, T, Tobe, K, Yamaguchi, M

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Safety and effectiveness of ipragliflozin in Japanese patients with type 2 diabetes mellitus and impaired renal function: subgroup analysis of a 3-year post-marketing surveillance study (STELLA-LONG TERM) by Tobe, K., Maegawa, H., Nakamura, I., Uno, S.

“…STELLA-LONG TERM, a 3-year post-marketing surveillance study, evaluated the safety and effectiveness of the sodiumglucose cotransporter 2 inhibitor…”
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Relationship between body mass index and periodontitis in young Japanese adults by Ekuni, D., Yamamoto, T., Koyama, R., Tsuneishi, M., Naito, K., Tobe, K.

“…Background and Objective:  Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship…”
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Seed Germination and Seedling Emergence of Three Annuals Growing on Desert Sand Dunes in China by TOBE, KAZUO, ZHANG, LIPING, OMASA, KENJI

“…• Background and Aims Information on the initial growth characteristics of annuals found in Chinese deserts is very limited. The aim of this study was to…”
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Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity by Tsuchida, Atsushi, Yamauchi, Toshimasa, Ito, Yusuke, Hada, Yusuke, Maki, Toshiyuki, Takekawa, Sato, Kamon, Junji, Kobayashi, Masaki, Suzuki, Ryo, Hara, Kazuo, Kubota, Naoto, Terauchi, Yasuo, Froguel, Philippe, Nakae, Jun, Kasuga, Masato, Accili, Domenico, Tobe, Kazuyuki, Ueki, Kohjiro, Nagai, Ryozo, Kadowaki, Takashi

“…Adiponectin/Acrp30 is a hormone secreted by adipocytes, which acts as an antidiabetic and antiatherogenic adipokine. We reported previously that AdipoR1 and…”
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A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes by HARA, K, TOBE, K, OKADA, T, KADOWAKI, H, AKANUMA, Y, ITO, C, KIMURA, S, KADOWAKI, T

“…Peroxisome proliferator activated receptor gamma coactivator-1 (PGC-1), a transcriptional coactivator of the nuclear receptor PPARgamma, plays a role in…”
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SIRT1 and FOXO1 mRNA expression in PBMC correlates to physical activity in COPD patients by Taka, Chihiro, Hayashi, Ryuji, Shimokawa, Kazuki, Tokui, Kotaro, Okazawa, Seisuke, Kambara, Kenta, Inomata, Minehiko, Yamada, Toru, Matsui, Shoko, Tobe, Kazuyuki

“…Physical activity (PA) is considered as one of the most important prognostic predictors in chronic obstructive pulmonary disease (COPD) patients. Longevity…”
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Observation of orbital waves as elementary excitations in a solid by Tokura, Y, Saitoh, E, Okamoto, S, Takahashi, K. T, Tobe, K, Yamamoto, K, Kimura, T, Ishihara, S, Maekawa, S

“…A basic concept in solid-state physics is that when some kind of symmetry in a solid is spontaneously broken, collective excitations will arise. For example,…”
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Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population by Imamura, M., Iwata, M., Maegawa, H., Watada, H., Hirose, H., Tanaka, Y., Tobe, K., Kaku, K., Kashiwagi, A., Kawamori, R., Nakamura, Y., Maeda, S.

“…Aims/hypothesis Recently, rs10906115 in CDC123/CAMK1D , rs1359790 near SPRY2 , rs1436955 in C2CD4A/C2CD4B and rs10751301 in ODZ4 were identified as genetic…”
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Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats by Okuno, A, Tamemoto, H, Tobe, K, Ueki, K, Mori, Y, Iwamoto, K, Umesono, K, Akanuma, Y, Fujiwara, T, Horikoshi, H, Yazaki, Y, Kadowaki, T

“…Troglitazone (CS-045) is one of the thiazolidinediones that activate the peroxisome proliferator-activated receptor gamma (PPARgamma), which is expressed…”
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Portomesenteric venous gas and pneumatosis cystoides intestinalis in systemic sclerosis by Ogawa, R, Taki, H, Tobe, K

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Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia by KUBOTA, Naoto, TOBE, Kazuyuki, SATOH, Shinobu, SEKIHARA, Hisahiko, SCIACCHITANO, Salvatore, LESNIAK, Maxine, AIZAWA, Shinichi, NAGAI, Ryozo, KIMURA, Satoshi, AKANUMA, Yasuo, TAYLOR, Simeon I, KADOWAKI, Takashi, TERAUCHI, Yasuo, ETO, Kazuhiro, YAMAUCHI, Toshimasa, SUZUKI, Ryo, TSUBAMOTO, Yoshiharu, KOMEDA, Kajuro, NAKANO, Ryosuke, MIKI, Hiroshi

“…Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. N Kubota…”
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Neutrino oscillations in an SO(10) supersymmetric grand unified theory with U(2)xU(1){sup n} family symmetry by Blazek, T., Raby, S., Tobe, K.

“…In a previous paper we analyzed fermion masses (focusing on neutrino masses and mixing angles) in an SO(10) SUSY GUT with U(2)xU(1){sup n} family symmetry. The…”
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Lepton-flavor violation in the supersymmetric standard model with seesaw-induced neutrino masses by Hisano, J., Moroi, T., Tobe, K., Yamaguchi, M., Yanagida, T.

“…We examine the lepton-flavor violation caused by a Yukawa coupling matrix y ν, ij for right-handed neutrinos in the supersymmetric standard model. We stress…”
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Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes by Yamauchi, T, Waki, H, Kamon, J, Murakami, K, Motojima, K, Komeda, K, Miki, H, Kubota, N, Terauchi, Y, Tsuchida, A, Tsuboyama-Kasaoka, N, Yamauchi, N, Ide, T, Hori, W, Kato, S, Fukayama, M, Akanuma, Y, Ezaki, O, Itai, A, Nagai, R, Kimura, S, Tobe, K, Kagechika, H, Shudo, K, Kadowaki, T

“…PPARgamma is a ligand-activated transcription factor and functions as a heterodimer with a retinoid X receptor (RXR). Supraphysiological activation of…”
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Deletion of platelet-derived growth factor receptor-β improves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice by Suzuki, H., Usui, I., Kato, I., Oya, T., Kanatani, Y., Yamazaki, Y., Fujisaka, S., Senda, S., Ishii, Y., Urakaze, M., Mahmood, A., Takasawa, S., Okamoto, H., Kobayashi, M., Tobe, K., Sasahara, M.

“…Aims/hypothesis The activation of platelet-derived growth factor receptor-β (PDGFR-β) signalling is increased in the glomeruli and tubules of diabetic animals…”
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Anisotropic optical spectra of doped manganites with pseudocubic perovskite structure by Tobe, K., Kimura, T., Tokura, Y.

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