Search Results - "TKESHELASHVILI, L K"

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  1. 1

    Mutation spectrum of copper-induced DNA damage by Tkeshelashvili, L K, McBride, T, Spence, K, Loeb, L A

    Published in The Journal of biological chemistry (05-04-1991)
    “…The ability of metal ions to damage DNA and cause mutagenesis has been analyzed with reversion and forward mutation assays using single-stranded DNA templates…”
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    Journal Article
  2. 2

    Nickel induces a signature mutation for oxygen free radical damage by TKESHELASHVILI, L. K, REID, T. M, MCBRIDE, T. J, LOEB, L. A

    Published in Cancer research (Chicago, Ill.) (15-09-1993)
    “…We have determined the specificity of mutations produced by nickel(II), a known human carcinogen, in a forward mutation assay and also used a sensitive…”
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  3. 3

    Effect of some nickel compounds on red blood cell characteristics by Tkeshelashvili, L K, Tsakadze, K J, Khulusauri, O V

    Published in Biological trace element research (01-07-1989)
    “…The effect of certain inorganic and coordinated nickel compounds on the resistance to different destructive substances, rheological properties, and functional…”
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  4. 4

    Metal-induced lethality and mutagenesis: possible role of apurinic intermediates by Schaaper, R M, Koplitz, R M, Tkeshelashvili, L K, Loeb, L A

    Published in Mutation research (01-04-1987)
    “…The possible mechanisms by which various metals exert their mutagenic effects were investigated using both chemical and biochemical techniques. Ions of Cu, Ni…”
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  5. 5

    Metal-induced infidelity of DNA synthesis by Zakour, R A, Tkeshelashvili, L K, Shearman, C W, Koplitz, R M, Loeb, L A

    “…A number of metals have been demonstrated to be mutagens in procaryotic and eucaryotic organisms as well as carcinogens in experimental animals. Epidemiologic…”
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    Effects of arsenic, selenium, and chromium on the fidelity of DNA synthesis by Tkeshelashvili, L K, Shearman, C W, Zakour, R A, Koplitz, R M, Loeb, L A

    Published in Cancer research (Chicago, Ill.) (01-07-1980)
    “…The effect of three environmentally important metals, arsenic, selenium, and chromium, on the accuracy of DNA synthesis in vitro has been analyzed. The…”
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    Comparative study of nucleosome particles in chromatin from normal and tumor cells. I. Structural parameters by Sapozhnikova, N A, Ramm, E I, Ivanov, G S, Tkeshelashvili, L K, Vorob'ev, V I

    Published in Molekuliarnaia biologiia (01-09-1988)
    “…The composition and structure of nucleosomic fragments isolated from the ascitic hepatoma 22A cells, liver and from cells of C3HA mice in norm and after…”
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  13. 13

    Concentration of DNA divalent ions in transformed tissues during exposure to various factors by Tkeshelashvili, L K, Matevosian, A E, Kiladze, A A, Lordkipanidze, A T

    Published in Biofizika (01-03-1985)
    “…The effect of X-irradiation (1000 r) on the rat liver nuclear DNA Zn content has been studied. The results show a significant decrease of Zn content 1 hour…”
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  14. 14

    Ca2+, Mg2+, Zn2+ levels in histone fractions from normal and tumor cells by Tkeshelashvili, L K, Sichinava, N V, Sapozhnikova, N A, Rcheulishvili, A N

    Published in Biofizika (01-07-1983)
    “…Distribution of some bivalent cations (Ca2+, Mg2+, Zn2+) in histones isolated from healthy mice liver and ascitic hepatoma 22A cells has been investigated by…”
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    Possibility of migration of several elements in biological systems following x-irradiation by Andronikashvili, E L, Mosulishvili, L M, Tkeshelashvili, L K, Rcheulishvili, A N, Matevosian, A E

    “…The effect of local X-irradiation on the content of trace elements of subcellular fractions (nuclear, mitochondrial) and the blood serum of rats with sarcoma…”
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