Search Results - "TISCHLER, Verena"
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Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
Published in BMC cancer (24-01-2012)“…Several stromal cell subtypes including macrophages contribute to tumor progression by inducing epithelial-mesenchymal transition (EMT) at the invasive front,…”
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2
Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State
Published in Cell (02-03-2012)“…Regulatory networks orchestrated by key transcription factors (TFs) have been proposed to play a central role in the determination of stem cell states…”
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3
Prognostic Significance of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transition Protein Expression in Non–Small Cell Lung Cancer
Published in Clinical cancer research (15-11-2008)“…Purpose: In carcinomas, invasive tumor growth is accompanied by desmoplastic stroma reaction and facilitated by epithelial-mesenchymal transition (EMT) of…”
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4
Mechanisms of Primary Drug Resistance in FGFR1 -Amplified Lung Cancer
Published in Clinical cancer research (15-09-2017)“…The 8p12-p11 locus is frequently amplified in squamous cell lung cancer (SQLC); the receptor tyrosine kinase fibroblast growth factor receptor 1 (FGFR1) being…”
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5
Periostin is up-regulated in high grade and high stage prostate cancer
Published in BMC cancer (09-06-2010)“…Expression of periostin is an indicator of epithelial-mesenchymal transition in cancer but a detailed analysis of periostin expression in prostate cancer has…”
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6
L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer
Published in Molecular cancer (10-10-2011)“…The L1 cell adhesion molecule (L1CAM) is potentially involved in epithelial-mesenchymal transition (EMT). EMT marker expression is of prognostic significance…”
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7
Primate genome architecture influences structural variation mechanisms and functional consequences
Published in Proceedings of the National Academy of Sciences - PNAS (24-09-2013)“…Although nucleotide resolution maps of genomic structural variants (SVs) have provided insights into the origin and impact of phenotypic diversity in humans,…”
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Correction to: Epigenetic regulation of L1CAM in endometrial carcinoma: comparison to cancer-testis (CT-X) antigens
Published in BMC cancer (29-10-2018)“…Following publication of the original article [1], we have been alerted to errors in Figs. 2 and 8. In Fig. 2B, the GAPDH loading control for Hec1A cells is…”
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Training increases concordance in classifying pulmonary adenocarcinomas according to the novel IASLC/ATS/ERS classification
Published in Virchows Archiv : an international journal of pathology (01-08-2012)“…The International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS), and the European Respiratory Society (ERS) proposed a…”
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10
A role for ADAM12 in breast tumor progression and stromal cell apoptosis
Published in Cancer research (Chicago, Ill.) (01-06-2005)“…As in developmental and regenerative processes, cell survival is of fundamental importance in cancer. Thus, a tremendous effort has been devoted to dissecting…”
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11
Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression
Published in FEBS letters (19-11-2004)“…The redox regulator thioredoxin-1 (Trx-1) is required for the redox potential of the cell and exerts important functions in cell growth and apoptosis. Severe…”
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12
Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient
Published in The Journal of heart and lung transplantation (01-09-2012)“…We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with…”
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13
Current Topics and Practical Considerations of Cytology Practice in Lung Cancer: Reflexions from the Lung Symposium at the 42nd European Congress of Cytology, Malmö, 2019
Published in Acta cytologica (01-09-2020)“…In June 2019, a lung symposium was held at the 42nd European Congress of Cytology in Malmö, Sweden. Due to the current importance of cytological samples in the…”
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14
Cathepsin D and H2O2 Stimulate Degradation of Thioredoxin-1
Published in The Journal of biological chemistry (30-12-2005)“…Cathepsin D (CatD) is a lysosomal aspartic proteinase and plays an important role in the degradation of proteins and in apoptotic processes induced by…”
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LACTB is a tumour suppressor that modulates lipid metabolism and cell state
Published in Nature (London) (30-03-2017)“…Post-mitotic, differentiated cells exhibit a variety of characteristics that contrast with those of actively growing neoplastic cells, such as the expression…”
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Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors
Published in Nature communications (13-03-2018)“…Pulmonary large-cell neuroendocrine carcinomas (LCNECs) have similarities with other lung cancers, but their precise relationship has remained unclear. Here we…”
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17
Mass Spectrometry-Based Profiling of Histone Post-Translational Modifications in Uveal Melanoma Tissues, Human Melanocytes, and Uveal Melanoma Cell Lines - A Pilot Study
Published in Investigative ophthalmology & visual science (01-02-2024)“…Epigenetic alterations in uveal melanoma (UM) are still neither well characterized, nor understood. In this pilot study, we sought to provide a deeper insight…”
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Prognostic Impact of KRAS G12C Mutation in Patients With NSCLC: Results From the European Thoracic Oncology Platform Lungscape Project
Published in Journal of thoracic oncology (01-06-2021)“…KRAS mutations, the most frequent gain-of-function alterations in NSCLC, are currently emerging as potential predictive therapeutic targets. The role of…”
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Gemcitabine Synergizes with Immune Checkpoint Inhibitors and Overcomes Resistance in a Preclinical Model and Mesothelioma Patients
Published in Clinical cancer research (15-12-2018)“…Combination of immune checkpoint inhibitors with chemotherapy is under investigation for cancer treatment. We studied the rationale of such a combination for…”
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Update thoracic pathology 2022-Report of the Thoracic Pathology Working Group of the German Society of Pathology
Published in Pathologie (Heidelberg, Germany) (01-08-2022)Get more information
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