Search Results - "TIPPMER, S"
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Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase
Published in The Journal of biological chemistry (04-02-1994)“…Rat-1 fibroblasts stably overexpressing high levels of human insulin receptor were used as a model system to study the effects of hyperglycemia on insulin…”
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Acute hyperglycemia provides an insulin-independent inducer for GLUT4 translocation in C2C12 myotubes and rat skeletal muscle
Published in Diabetes (New York, N.Y.) (01-06-1995)“…Acute hyperglycemia provides an insulin-independent inducer for GLUT4 translocation in C2C12 myotubes and rat skeletal muscle. P Galante , L Mosthaf , M…”
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Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts
Published in Diabetes (New York, N.Y.) (01-03-1994)“…Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts. M Kellerer , G Kroder , S Tippmer , L Berti , R Kiehn , L…”
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Glucosamine induces translocation of protein kinase C isoenzymes in mesangial cells
Published in Experimental and clinical endocrinology & diabetes (1998)“…Activation of protein kinase C (PKC) has been implicated in the high glucose-induced stimulation of matrix protein production in mesangial cells. Since we have…”
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Modulation of insulin receptor signaling. Potential mechanisms of a cross talk between bradykinin and the insulin receptor
Published in Diabetes (New York, N.Y.) (01-01-1996)“…Insulin resistance of the skeletal muscle plays a key role in the development of the metabolic endocrine syndrome and its further progression to type II…”
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Regulation of the mannose 6‐phosphate/IGF II receptor expression at the cell surface by mannose 6‐phosphate, insulin like growth factors and epidermal growth factor
Published in The EMBO journal (01-03-1989)“…Mannose 6‐phosphate, insulin like growth factors I and II (IGF I, IGF II), insulin and epidermal growth factor (EGF) induce a 1.5‐ to 2‐fold increase of…”
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Normal insulin receptor tyrosine kinase activity and glucose transporter (GLUT 4) levels in the skeletal muscle of hyperinsulinaemic hypertensive rats
Published in Diabetologia (01-08-1992)“…The spontaneous hypertensive rat is an animal model characterized by a syndrome of hypertension, insulin resistance and hyperinsulinaemia. To elucidate whether…”
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Insulin-like growth factors I and II stimulate endocytosis but do not affect sorting of lysosomal enzymes in human fibroblasts
Published in The Journal of biological chemistry (25-04-1990)“…The mannose 6-phosphate (Man-6-P)/insulin-like growth factor (IGF) II receptor has separate binding sites for Man-6-P and IGF II. It targets newly synthesized…”
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10
Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts
Published in Diabetes (New York, N.Y.) (01-03-1994)“…Troglitazone (CS045), a compound belonging to the thiazolidine diones, is being tested as a new oral antidiabetic agent. Evidence exists from animal studies…”
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Acute hyperglycemia provides an insulin-independent inducer for GLUT4 translocation in C2C12 myotubes and rat skeletal muscle
Published in Diabetes (New York, N.Y.) (01-06-1995)“…GLUT4 translocation and activation of glucose uptake in skeletal muscle can be induced by both physiological (i.e., insulin, nerve stimulation, or exercise)…”
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Distinct .alpha.-subunit structures of human insulin receptor A and B variants determine differences in tyrosine kinase activities
Published in Biochemistry (Easton) (19-05-1992)“…Human insulin receptor isoforms (HIR-A and -B) differ in their alpha-subunit structures which result from alternatively spliced precursor mRNAs. This…”
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The nucleotide and partial amino acid sequences of rat fetuin : identity with the natural tyrosine kinase inhibitor of the rat insulin receptor
Published in European journal of biochemistry (01-03-1992)“…Fetuins are among the major plasma proteins, yet their biological role has remained elusive. Here we report the molecular cloning of rat fetuin and the…”
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Bradykinin Induces Tyrosine Phosphorylation in Human Foreskin Fibroblasts and 293 Cells Transfected with Rat B2 Kinin Receptor
Published in European journal of biochemistry (15-03-1996)“…The intracellular effects of bradykinin are mediated through the recently cloned B2 kinin receptor which belongs to the superfamily of receptors with seven…”
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Mannose 6-phosphate/insulin-like growth factor II receptor in I-cell disease fibroblasts: increased synthesis and defective regulation of cell surface expression
Published in Biochimica et biophysica acta (14-04-1992)“…The amount of mannose 6-phosphate/IGF II receptors in fibroblasts from five I-cell patients was about 2-fold higher than in control fibroblasts. The elevated…”
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Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta
Published in European journal of biochemistry (01-10-1994)“…Bradykinin exerts a broad spectrum of cellular effects on different tissues. It is believed that these effects are predominantly mediated by the recently…”
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Regulation of mannose 6‐phosphate/insulin‐like growth factor II receptor distribution by activators and inhibitors of protein kinase C
Published in European journal of biochemistry (20-05-1990)“…The tumor‐promotor phorbol dibutyrate (PDBt) increases the binding of a neoglycoprotein containing mannose 6‐phosphate (Man6P) and of insulin‐like growth…”
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