Search Results - "TINDLE, R. W"

A "public" T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes by TINDLE, R. W, FERNANDO, G. J. P, STERLING, J. C, FRAZER, I. H

“…We have identified a major T-cell epitope, amino acids 48-54 (DRAHYNI, in one-letter code) in the E7 open reading frame protein of human papillomavirus (HPV)…”
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Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization by DOAN, T, HERD, K. A, LAMBERT, P. F, FERNANDO, G. J. P, STREET, M. D, TINDLE, R. W

“…The E7 oncoprotein of human papillomavirus 16 functions as a tumor-specific antigen in transformed epithelial cells of the uterine cervix to which…”
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Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells by Smeland, E B, Funderud, S, Kvalheim, G, Gaudernack, G, Rasmussen, A M, Rusten, L, Wang, M Y, Tindle, R W, Blomhoff, H K, Egeland, T

“…Immunomagnetic beads are well suited for positive selection of CD34+ cells. However, both unspecific binding of beads to cells as well as the effectiveness of…”
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A vaccine conjugate of ‘ISCAR’ immunocarrier and peptide epitopes of the E7 cervical cancer‐associated protein of human papillomavirus type 16 elicits specific Th1‐ and Th2‐type responses in immunized mice in the absence of oil‐based adjuvants by TINDLE, R. W., CROFT, S., HERD, K., MALCOLM, K., GECZY, A. F., STEWART, T., FERNANDO, G. J. P.

“…SUMMARY TraT protein, known as ISCAR (= Immunostimulatory Carrier), is one of a family of integral membrane proteins (Imps) of Escherichia coli representing…”
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Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease by FRAZER, I. H, LEIPPE, D. M, DUNN, L. A, LIEM, A, TINDLE, R. W, FERNANDO, G. J. P, PHELPS, W. C, LAMBERT, P. F

“…The human papillomavirus (HPV) oncogenes, E6 and E7, are believed to contribute to the development of cervical cancers in women infected with certain HPV…”
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Nonspecific Down-Regulation of CD8+T-Cell Responses in Mice Expressing Human Papillomavirus Type 16 E7 Oncoprotein from the Keratin-14 Promoter by Tindle, R W, Herd, K, Doan, T, Bryson, G, Leggatt, G R, Lambert, P, Frazer, I H, Street, M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human papillomavirus (HPV) type 18 E7 protein is a short-lived steroid-inducible phosphoprotein in HPV-transformed cell lines by Selvey, L. A, Dunn, L. A, Tindle, R. W, Park, D. S, Frazer, I. H

“…Papillomavirus Research Unit, Lions Human Immunology Laboratories, University of Queensland, Princess Alexandra Hospital, Woollongabba 4102, Queensland,…”
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Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen by Patricia Londoño, L., Chatfield, Steven, Tindle, Robert W., Herd, Karen, Gao, Xiao-Ming, Frazer, Ian, Dougan, Gordon

“…Live vaccines based on BRD509, an attenuated S. typhimurium (aroA, aroD) strain, were constructed that directed the expression of hepatitis B core antigen…”
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Peripheral T-Cell Tolerance Defined through Transgenic Mouse Studies by Tindle, Robert W.

“…Selection in the thymus restricted by MHC and self-peptide shapes the diverse reactivities of the T-cell population which subsequently seeds into the…”
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Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the Hepatitis B core antigen (HBcAg) c/e1-region by Street, M, Herd, K, Londono, P, Doan, T, Dougan, G, Kast, W. M, Tindle, R. W

“…Work from a number of laboratories including our own has shown that foreign B-epitopes inserted into the c/e1-region of Hepatitis B core antigen (HBcAg) elicit…”
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Vaccine‐Induced Th1‐Type Responses are Dominant over Th2‐Type Responses in the Short Term whereas Pre‐existing Th2 Responses are Dominant in the Longer Term by Fernando, G J, Stewart, T J, Tindle, R W, Frazer, I H

“…The effect of adjuvant on induction of human papillomavirus type 16 E7 protein‐specific cytotoxic T lymphocytes (CTL) and immunoglobulin G (IgG)2a antibody was…”
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E7 Oncoprotein of Human Papillomavirus Type 16 Expressed Constitutively in the Epidermis Has No Effect on E7-Specific B- or Th-Repertoires or on the Immune Response Induced or Sustained after Immunization with E7 Protein by Herd, K., Fernando, G.J.P., Dunn, L.A., Frazer, I.H., Lambert, P., Tindle, R.W.

“…A line of FVB (H-2q) mice transgenic for the E6/E7 open reading frames of Human Papillomavirus type 16 driven from the α-A crystallin promoter expresses E7…”
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Human papillomavirus vaccines for cervical cancer by Tindle, R W

“…The association of carcinoma of the uterine cervix with human papillomavirus indicates that vaccine strategies which target the virus could be useful in the…”
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Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumour by Herd, Karen A., Harvey, Tracey, Khromykh, Alexander A., Tindle, Robert W.

“…The persistence of the E7 oncoprotein in transformed cells in human papillomavirus (HPV)-associated cervical cancer provides a tumour-specific antigen to which…”
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Identification of B epitopes in human papillomavirus type 16 E7 open reading frame protein by Tindle, Robert W, Smith, Judy A, Geysen, H. Mario, Selvey, Linda A, Frazer, Ian H

“…1 Lions Human Immunology Laboratories, Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland 4102 and 2…”
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Capture ELISA and in vitro cell binding assay for the detection of antibodies to human papillomavirus type 6b virus-like particles in patients with anogenital warts by Peng, Shiwen, Qi, Yingmei, Christensen, Neil, Hengst, Kylie, Kennedy, Lynn, Frazer, Ian H., Tindle, Robert W.

“…To investigate human papillomavirus (HPV) virus-like particle (VLP)-specific antibody responses among anogenital warts patients, a VLP-based capture ELISA was…”
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Potential strategies utilised by papillomavirus to evade host immunity by Frazer, Ian H., Thomas, Ranjeny, Zhou, Jian, Leggatt, Graham R., Dunn, Linda, McMillan, Nigel, Tindle, Robert W., Filgueira, Luis, Manders, Peter, Barnard, Paula, Sharkey, Michael

“…The co‐evolution of papillomaviruses (PV) and their mammalian hosts has produced mechanisms by which PV might avoid specific and non‐specific host immune…”
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A polytope DNA vaccine elicits multiple effector and memory CTL responses and protects against human papillomavirus 16 E7-expressing tumour by DOAN, Tracy, HERD, Karen, RAMSHAW, Ian, THOMSON, Scott, TINDLE, Robert W

“…Vaccine-induced CD8 T cells directed to tumour-specific antigens are recognised as important components of protective and therapeutic immunity against tumours…”
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Limitations of HLA‐transgenic mice in presentation of HLA‐restricted cytotoxic T‐cell epitopes from endogenously processed human papillomavirus type 16 E7 protein by Street, Michael D., Doan, Tracy, Herd, Karen A., Tindle, Robert W.

“…Summary We investigated the use of mice transgenic for human leucocyte antigen (HLA) A*0201 antigen‐binding domains to test vaccines composed of defined HLA…”
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Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients by Stacey, S N, Ghosh, A, Bartholomew, J S, Tindle, R W, Stern, P L, Mackett, M, Arrand, J R

“…Although the presence of serum antibodies against the human papillomavirus type 16 (HPV-16) E7 protein has been linked with cervical cancer, currently…”
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