Search Results - "TIMPL, R"

Perinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice by Kostka, Günter, Giltay, Richard, Bloch, Wilhelm, Addicks, Klaus, Timpl, Rupert, Fässler, Reinhard, Chu, Mon-Li

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing by Bloch, Wilhelm, Huggel, Katharina, Sasaki, Takako, Grose, Richard, Bugnon, Philippe, Addicks, Klaus, Timpl, Rupert, Werner, Sabine

“…ABSTRACT Endostatin is a cleavage product of collagen XVIII that strongly inhibits tumor angiogenesis. To determine if endostatin affects other angiogenic…”
Get full text

Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis by Kadoya, K., Sasaki, T., Kostka, G., Timpl, R., Matsuzaki, K., Kumagai, N., Sakai, L.Y., Nishiyama, T., Amano, S.

“…Summary Background  Fibulin‐5 was recently found as a secreted extracellular matrix protein that functions as a scaffold for elastic fibres. However, the…”
Get full text

Selective recognition of cyclic RGD peptides of NMR defined conformation by αIIbβ3, αVβ3, and α5β1 integrins by PFAFF, M, TANGEMANN, K, MÜLLER, B, GURATH, M, MÜLLER, G, KESSLER, H, TIMPL, R, ENGEL, J

Get full text

Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV by Fox, J.W., Mayer, U., Nischt, R., Aumailley, M., Reinhardt, D., Wiedemann, H., Mann, K., Timpl, R., Krieg, T., Engel, J.

“…Recombinant mouse nidogen and two fragments were produced in mammalian cells and purified from culture medium without resorting to denaturing conditions. The…”
Get full text

Proteoglycans of basement membranes by Timpl, R

“…Proteoglycans carrying either heparan sulfate and/or chondroitin sulfate side chains are typical constituents of basement membranes. The most prominent…”
Get full text

The heparin‐binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival by Edgar, D., Timpl, R., Thoenen, H.

“…The survival of cultured chick sympathetic neurons and the outgrowth of neurites were stimulated by the basement membrane protein laminin coated onto…”
Get full text

A single EGF‐like motif of laminin is responsible for high affinity nidogen binding by Mayer, U., Nischt, R., Pöschl, E., Mann, K., Fukuda, K., Gerl, M., Yamada, Y., Timpl, R.

“…A major nidogen binding site of mouse laminin was previously localized to about three EGF‐like repeats (Nos 3–5) of its B2 chain domain III [M. Gerl et al…”
Get full text

Calcium Affinity, Cooperativity, and Domain Interactions of Extracellular EF-hands Present in BM-40 by Busch, Elisabeth, Hohenester, Erhard, Timpl, Rupert, Paulsson, Mats, Maurer, Patrik

“…The structure and function of cytosolic Ca2+-binding proteins containing EF-hands are well understood. Recently, the presence of EF-hands in an extracellular…”
Get full text

Binding of the proteoglycan decorin to collagen type VI by BIDANSET, D, GUIDRY, C, ROSENBERG, L. C, CHOI, H. U, TIMPL, R, HOOK, M

“…We have examined the interactions between the small dermatan sulfate proteoglycan decorin and collagen types I-VI using solid phase binding assays. The results…”
Get full text

Role of mesenchymal nidogen for epithelial morphogenesis in vitro by EKBLOM, P, EKBLOM, M, FECKER, L, KLEIN, G, HONG-YAN ZHANG, KADOYA, Y, MON-LI CHU, MAYER, U, TIMPL, R

“…Recent biochemical studies suggested that the extracellular matrix protein nidogen is a binding molecule linking together basement membrane components. We…”
Get full text

Integrin Recognition of Different Cell-Binding Fragments of Laminin (P1, E3, E8) and Evidence That α6β1 but Not α6β4 Functions as a Major Receptor for Fragment E8 by Sonnenberg, A., Linders, C. J. T., Modderman, P. W., Damsky, C. H., Aumailley, M., Timpl, R.

“…The involvement of integrins in mediating interaction of cells to well-characterized proteolytic fragments (P1, E3, and E8) of laminin was assessed by antibody…”
Get full text

The collagen superfamily by Brown, J C, Timpl, R

“…The collagens represent a large family of molecular proteins which are located in the extracellular matrix. They all share a triple-helical segment of variable…”
Get more information

Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily by Hohenester, Erhard, Sasaki, Takako, Timpl, Rupert

“…Scavenger receptor cysteine-rich (SRCR) domains are found widely in cell surface molecules and in some secreted proteins, where they are thought to mediate…”
Get full text

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures by UTANI, A, NOMIZU, M, TIMPL, R, ROLLER, P. P, YAMADA, Y

“…The assembly of laminin chains into double- and triple-stranded structures was studied with recombinant proteins derived from the C-terminal alpha-helical…”
Get full text

Recognition of the Laminin E8 Cell-Binding Site by an Integrin Possessing the α 6 Subunit Is Essential for Epithelial Polarization in Developing Kidney Tubules by Sorokin, Lydia, Sonnenberg, Arnoud, Aumailley, Monique, Timpl, Rupert, Ekblom, Peter

“…It has been previously shown that A-chain and domain(E8)-specific antibodies to laminin that inhibit cell adhesion also interfere with the establishment of…”
Get full text

Macromolecular organization of basement membranes by Timpl, Rupert

“…A considerable variety of basement membrane components, including in particular more than ten laminin isoforms and their novel α chains (α3, α4 and α5), has…”
Get full text

Attachment of Cells to Basement Membrane Collagen Type IV by Aumailley, Monique, Timpl, Rupert

“…Of ten different cell lines examined, three showed distinct attachment and spreading on collagen IV substrates, and neither attachment nor spreading was…”
Get full text

Multimeric vitronectin. Identification and characterization of conformation-dependent self-association of the adhesive protein by Stockmann, A, Hess, S, Declerck, P, Timpl, R, Preissner, K.T.

“…The adhesive glycoprotein vitronectin (VN) shows a high degree of conformational flexibility implicating that different molecular forms of the molecular may…”
Get full text

Increased expression of type VI collagen in lung fibrosis by Specks, U, Nerlich, A, Colby, T V, Wiest, I, Timpl, R

“…Pulmonary fibrosis is characterized by disturbances of extracellular matrix protein deposition resulting from fibroblast activation and proliferation. Collagen…”
Get more information