Search Results - "TILLETT, William"

Improvement in work productivity among psoriatic arthritis patients treated with biologic or targeted synthetic drugs: a systematic literature review and meta-analysis by Gossec, Laure, Humphries, Brittany, Rutherford, Megan, Taieb, Vanessa, Willems, Damon, Tillett, William

“…Capacity to work is impacted by psoriatic arthritis (PsA). Our objective was to describe the course of work productivity and leisure activity in patients with…”
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Nail psoriasis dynamics during biologic treatment and withdrawal in patients with psoriasis who may be at high risk of developing psoriatic arthritis: a post hoc analysis of the VOYAGE 2 randomized trial by Tillett, William, Egeberg, Alexander, Sonkoly, Enikö, Gorecki, Patricia, Tjärnlund, Anna, Buyze, Jozefien, Wegner, Sven, McGonagle, Dennis

“…Abstract Background Nail psoriasis is a common, physiologically, and psychologically disruptive, and yet often under-treated manifestation of psoriasis. The…”
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Dramatic effects of a new antimicrobial stewardship program in a rural community hospital by Libertin, Claudia R., Watson, Stephanie H., Tillett, William L., Peterson, Joy H.

“…•Rural hospitals of <100 occupied bed days benefit from new antimicrobial stewardship.•Dramatically decreased Clostridium difficile infection rates occurred in…”
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Impact of psoriatic arthritis and comorbidities on ustekinumab outcomes in psoriasis: a retrospective, observational BADBIR cohort study by Tillett, William, Ogdie, Alexis, Passey, Alun, Gorecki, Patricia

“…ObjectivesPsoriasis and psoriatic arthritis (PsA) are independently associated with comorbidities, including obesity and metabolic syndrome, which may impact…”
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Filling the “GAP” in Real-World Assessment of Psoriatic Arthritis Disease Activity: Performance Characteristics of a Global/Pain Composite Endpoint by Tillett, William, Birt, Julie, Vadhariya, Aisha, Ross, Sarah, Ngantcha, Marcus, Ng, Khai Jing

“…Introduction Some retrospective data sources, such as electronic health records in the USA, report composite outcome measures not fully validated in psoriatic…”
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Qualitative interview study of rheumatology patients’ experiences of COVID-19 shielding to explore the physical and psychological impact and identify associated support needs by Silverthorne, Christine A, Jones, Bethan, Brooke, Mel, Coates, Laura C, Orme, Jen, Robson, Joanna C, Tillett, William, Dures, Emma

“…ObjectiveMany clinically extremely vulnerable rheumatology patients have only recently ceased shielding from COVID-19, while some continue to minimise…”
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Effectiveness of sequential lines of biologic and targeted small molecule drugs in psoriasis: A systematic review and meta‐analysis by Gollins, Charlotte E., Vincent, Rosie, Fahy, Caoimhe, McHugh, Neil, Tillett, William

“…To assess current evidence of effectiveness of sequential lines of biologic and targeted small molecule drugs for psoriasis beyond first line. A systematic…”
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A Threshold of Meaning for Work Disability Improvement in Psoriatic Arthritis Measured by the Work Productivity and Activity Impairment Questionnaire by Tillett, William, Lin, Chen-Yen, Zbrozek, Art, Sprabery, Aubrey Trevelin, Birt, Julie

“…Introduction The Work Productivity and Activity Impairment Specific Health Problem Questionnaire (WPAI:SHP) is used to assess the impact of an intervention on…”
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Changes in musculoskeletal disease activity and patient-reported outcomes in patients with psoriatic arthritis treated with ixekizumab: results from a real-world US cohort by Tillett, William, Birt, Julie, Cavanaugh, Cristi, Jung, Yoojin, Vadhariya, Aisha, Ross, Sarah, Paulus, Jessica, Lubrano, Ennio

“…Ixekizumab has demonstrated efficacy in pivotal trials in patients with psoriatic arthritis (PsA), both those naïve to prior biologic therapy and those with…”
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The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to severe psoriatic arthritis: the 3-arm parallel group SPEED randomized controlled trial by Watson, Marion, Tillett, William, Jadon, Deepak, Massa, M Sofia, Francis, Anne, Gullick, Nicola, Rombach, Ines, Sinomati, Yvonne, Tucker, Laura, Coates, Laura C

“…The aim of the Severe Psoriatic arthritis - Early intervEntion to control Disease trial is to compare outcomes in psoriatic arthritis (PsA) patients with poor…”
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Early Improvements with Guselkumab Associate with Sustained Control of Psoriatic Arthritis: Post hoc Analyses of Two Phase 3 Trials by Curtis, Jeffrey R., Deodhar, Atul, Soriano, Enrique R., Rampakakis, Emmanouil, Shawi, May, Shiff, Natalie J., Han, Chenglong, Tillett, William, Gladman, Dafna D.

“…Introduction Patterns of treatment response can inform clinical decision-making. This study assessed the course and impact of achieving minimal clinically…”
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Bimekizumab provided rapid improvements in patient-reported symptoms and health-related quality of life in patients with active psoriatic arthritis: pooled 16-week results from two phase 3 studies by Husni, M Elaine, Mease, Philip J, Merola, Joseph F, Tillett, William, Goldammer, Nadine, Ink, Barbara, Coarse, Jason, Lambert, Jérémy, Taieb, Vanessa, Gladman, Dafna D

“…ObjectivesTo assess impact of bimekizumab treatment on patient-reported outcomes and health-related quality of life (HRQoL) in patients with active psoriatic…”
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Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design by Rombach, Ines, Tillett, William, Jadon, Deepak, Tucker, Laura, Watson, Marion, Francis, Anne, Sinomati, Yvonne, Eldridge, Lucy, Dritsaki, Melina, Dutton, Susan J, Al-Mossawi, Hussein, Gullick, Nicola, Thompson, Ben, Coates, Laura C

“…The Tight Control of psoriatic arthritis (TICOPA) trial confirmed improved clinical outcomes with a treat to target (T2T) strategy in psoriatic arthritis…”
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Association of achieving clinical disease control criteria and patient-reported outcomes in bimekizumab-treated patients with active psoriatic arthritis: results from two phase III studies by Kristensen, Lars Erik, Tillett, William, Nash, Peter, Coates, Laura C., Mease, Philip J., Ogdie, Alexis, Gisondi, Paolo, Ink, Barbara, Prickett, Adam R., Bajracharya, Rajan, Taieb, Vanessa, Lyris, Nikos, Lambert, Jérémy, Walsh, Jessica A.

“…Background: Psoriatic arthritis (PsA) is a chronic inflammatory disease that causes pain and fatigue, reduces physical function, and negatively impacts…”
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Disease Characteristics and the Burden of Joint and Skin Involvement Amongst People With Psoriatic Arthritis: A Population Survey by Tillett, William, Merola, Joseph F., Thaçi, Diamant, Holdsworth, Elizabeth, Booth, Nicola, Lobosco, L. Steve, Milligan, Gary, Hufford, Matthew M., Birt, Julie A., Boehncke, Wolf-Henning

“…Introduction Psoriatic arthritis (PsA) is a chronic, systemic, inflammatory disease where disease burden and quality of life (QoL) are affected by both joint…”
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Achievement of more stringent disease control is associated with reduced burden on workplace and household productivity: results from long-term certolizumab pegol treatment in patients with psoriatic arthritis by Tillett, William, Coates, Laura C., Kiri, Sandeep, Taieb, Vanessa, Willems, Damon, Mease, Philip J.

“…Background: Psoriatic arthritis (PsA) impacts the physical health and functional ability of patients, leading to reduced productivity. High unemployment rates…”
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Identification of PsA phenotypes with machine learning analytics using data from two phase III clinical trials of guselkumab in a bio-naïve population of patients with PsA by Richette, Pascal, Vis, Marijn, Ohrndorf, Sarah, Tillett, William, Ramírez, Julio, Neuhold, Marlies, van Speybroeck, Michel, Theander, Elke, Noel, Wim, Zimmermann, Miriam, Shawi, May, Kollmeier, Alexa, Zabotti, Alen

“…ObjectivesPsoriatic arthritis (PsA) phenotypes are typically defined by their clinical components, which may not reflect patients’ overlapping symptoms. This…”
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Work Productivity and General Health Through 2 Years of Guselkumab Treatment in a Phase 3 Randomized Trial of Patients With Active Psoriatic Arthritis by Curtis, Jeffrey R., McInnes, Iain B., Rahman, Proton, Gladman, Dafna D., Peterson, Steven, Yang, Feifei, Adejoro, Oluwakayode, Kollmeier, Alexa P., Shiff, Natalie J., Han, Chenglong, Shawi, May, Tillett, William, Mease, Philip J.

“…Introduction To evaluate the effect of guselkumab on work productivity and nonwork daily activity impairment and general health status through 2 years in…”
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Comparative early effectiveness across 14 PsA drugs and 5 classes of PsA treatment: 3-month results from the PRO-SPIRIT study by Kristensen, Lars Erik, Ng, Khai Jing, Ngantcha, Marcus, Morel, Jacques, Lubrano, Ennio, Tillett, William, Alten, Rieke, Chandran, Vinod, Martinez Ferrer, Àngels, Zhu, Baojin, Kennedy, Dominika, Holzkämper, Thorsten, Gullick, Nicola, Kronbergs, Andris, Fakhouri, Walid, de la Torre, Inmaculada, McGonagle, Dennis G

“…BackgroundThe psoriatic arthritis (PsA) Observational Study of Persistence of Treatment (PRO-SPIRIT) assesses effectiveness and persistence of real-world PsA…”
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Effect of upadacitinib on reducing pain in patients with active psoriatic arthritis or ankylosing spondylitis: post hoc analysis of three randomised clinical trials by McInnes, Iain B, Ostor, Andrew J K, Mease, Philip J, Tillett, William, Baraliakos, Xenofon, de Vlam, Kurt, Bessette, Louis, Lippe, Ralph, Maniccia, Anna, Feng, Dai, Gao, Tianming, Zueger, Patrick, Saffore, Christopher, Kato, Koji, Song, In-Ho, Deodhar, Atul

“…ObjectiveEvaluate the effect of upadacitinib on pain outcomes in patients with active psoriatic arthritis (PsA) or ankylosing spondylitis (AS) across 3…”
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