Search Results - "TICKU, Maharaj K"

Emerging Role of Epigenetics in the Actions of Alcohol by Shukla, Shivendra D., Velazquez, Jose, French, Samuel W., Lu, Shelly C., Ticku, Maharaj K., Zakhari, Samir

“…This review deals with the recent developments on the epigenetic effects of ethanol. A large body of data have come from studies in liver and in neuronal…”
Get full text

The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription by Qiang, Mei, Denny, Ashley, Chen, Jiguo, Ticku, Maharaj K, Yan, Bo, Henderson, George

“…The NMDA receptor represents a particularly important site of ethanol action in the CNS. We recently reported that NMDA receptor 2B (NR2B) gene expression was…”
Get full text

Chronic intermittent ethanol treatment selectively alters N-methyl-D-aspartate receptor subunit surface expression in cultured cortical neurons by Qiang, Mei, Denny, Ashley D, Ticku, Maharaj K

“…A chronic intermittent ethanol (CIE) exposure regimen consists of repeated episodes of ethanol intoxication and withdrawal. CIE treatment has been reported to…”
Get more information

Potential role of cAMP response element-binding protein in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells by Rani, C S Sheela, Qiang, Mei, Ticku, Maharaj K

“…We have shown previously that long-term ethanol treatment causes an up-regulation of N-methyl-D-aspartate (NMDA) receptor 2B subunit (NR2B) number and function…”
Get more information

Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons by Qiang, Mei, Rani, C S Sheela, Ticku, Maharaj K

“…Neuron-restrictive silencer factor (NRSF) is a transcriptional repressor of multiple neuronal genes. This study addressed the role of NRSF in…”
Get more information

Ethanol-mediated inhibition of mitogen-activated protein kinase phosphorylation in mouse brain by Kalluri, Haviryaji S.G, Ticku, Maharaj K

“…Ethanol (1.5–3.5 g/kg body weight) was administered intraperitoneally to mice and the phosphorylation of MAP (mitogen-activated protein) kinase in the cerebral…”
Get full text

Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands by Chen, Weibin, Wu, Huifang, Hernandez, R. Jason, Mehta, Ashok K., Ticku, Maharaj K., France, Charles P., Coop, Andrew

“…[Display omitted] Gamma-hydroxybutyric acid (GHB) is a drug of abuse, a therapeutic, and purportedly a neurotransmitter with a complex mechanism of action in…”
Get full text

Up-regulation of NMDA receptor subunits in rat brain following chronic ethanol treatment by Kalluri, Haviryaji S.G, Mehta, Ashok K, Ticku, Maharaj K

“…We investigated the effect of chronic ethanol administration and its withdrawal on the polypeptide levels of NMDA receptor subunits such as NR1, NR2A, and NR2B…”
Get full text

Role of AP‐1 in ethanol‐induced N‐methyl‐d‐aspartate receptor 2B subunit gene up‐regulation in mouse cortical neurons by Qiang, Mei, Ticku, Maharaj K.

“…Activator protein 1 (AP‐1) has been reported to regulate the gene expression in a wide variety of cellular processes in response to stimuli. In this study, we…”
Get full text

Effect of chronic administration of ethanol on the regulation of the δ-subunit of GABAA receptors in the rat brain by Marutha Ravindran, C.R, Mehta, Ashok K, Ticku, Maharaj K

“…Abstract In the present study, we investigated the effect of chronic ethanol (CE) administration on the polypeptide levels of the δ-subunit of GABAA receptors…”
Get full text

Characterization and Pharmacology of the GHB Receptor by Ticku, Maharaj K., Mehta, Ashok K.

“…Radioligand binding using [3H]NCS‐382, an antagonist of the GHB receptor, revealed specific binding sites in the rat cerebrocortical and hippocampal membranes…”
Get full text

An update on GABA A receptors by Mehta, Ashok K, Ticku, Maharaj K

“…Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our…”
Get full text

Effect of chronic administration of ethanol on the regulation of the δ-subunit of GABA A receptors in the rat brain by Marutha Ravindran, C.R., Mehta, Ashok K., Ticku, Maharaj K.

“…In the present study, we investigated the effect of chronic ethanol (CE) administration on the polypeptide levels of the δ-subunit of GABA A receptors and […”
Get full text

Characterization of the picrotoxin site of GABAA receptors by Mehta, Ashok K, Ticku, Maharaj K

“…This unit describes an in vitro assay for characterization of the picrotoxin site of GABAA receptors in rat brain membranes using various radioligands. Methods…”
Get more information

Comparison of chronic ethanol and chronic intermittent ethanol treatments on the expression of GABA A and NMDA receptor subunits by Sheela Rani, C.S., Ticku, Maharaj K.

“…We examined the mRNA and protein levels of GABA A and NMDA receptor (NMDAR) subunits in cultured mouse cortical neurons following exposure to chronic ethanol…”
Get full text

Effect of 5-Azacytidine on the Methylation Aspects of NMDA Receptor NR2B Gene in the Cultured Cortical Neurons of Mice by Marutha Ravindran, C. R., Ticku, Maharaj K.

“…Our previous study revealed that the exposure of the drug 5-Azacytidine and ethanol to the cultured cortical neurons of mice causes demethylation of cytosine…”
Get full text

Chronic Ethanol-mediated Up-regulation of the N-Methyl-D-aspartate Receptor Polypeptide Subunits in Mouse Cortical Neurons in Culture by Follesa, Paolo, Ticku, Maharaj K.

“…The goal of this study was to determine whether chronic ethanol-mediated up-regulation of the N-methyl-D-aspartate receptors (NMDAR) was associated with an…”
Get full text

Role of GABAA receptors in the ethanol-mediated inhibition of extracellular signal-regulated kinase by KALLURI, Haviryaji S. G, TICKU, Maharaj K

Get full text

Role of CpG islands in the up-regulation of NMDA receptor NR2B gene expression following chronic ethanol treatment of cultured cortical neurons of mice by Marutha Ravindran, C.R., Ticku, Maharaj K.

“…Our earlier studies have indicated that chronic ethanol treatment produces an increase in the rate of NR2B gene expression but acute ethanol treatment doesn’t…”
Get full text

Low concentrations of ethanol do not affect radioligand binding to the δ-subunit-containing GABAA receptors in the rat brain by Mehta, Ashok K, Marutha Ravindran, C.R, Ticku, Maharaj K

“…Abstract In the present study, we investigated the co-localization pattern of the δ subunit with other subunits of GABAA receptors in the rat brain using…”
Get full text