Search Results - "TIANNI ZHOU"
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Efficacy of High-Dose Chemotherapy and Three-Dimensional Conformal Radiation for Atypical Teratoid/Rhabdoid Tumor: A Report From the Children's Oncology Group Trial ACNS0333
Published in Journal of clinical oncology (10-04-2020)“…Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive, early-childhood brain tumor without standard effective treatment. To our knowledge, we conducted the…”
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Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma
Published in Journal of clinical oncology (20-04-2019)“…The Children's Oncology Group trial ACNS0121 estimated event-free survival (EFS) and overall survival for children with intracranial ependymoma treated with…”
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Randomized Study of Two Chemotherapy Regimens for Treatment of Low-Grade Glioma in Young Children: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (20-07-2012)“…PURPOSE Surgery is curative therapy for pediatric low-grade gliomas (LGGs) in areas of the brain amenable to complete resection. However, LGGs located in areas…”
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High-Risk Medulloblastoma: A Pediatric Oncology Group Randomized Trial of Chemotherapy Before or After Radiation Therapy (POG 9031)
Published in Journal of clinical oncology (10-08-2013)“…To compare event-free survival (EFS) in children with high-risk medulloblastoma randomly assigned to receive either chemotherapy before radiation or…”
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Outcome of Children With Metastatic Medulloblastoma Treated With Carboplatin During Craniospinal Radiotherapy: A Children's Oncology Group Phase I/II Study
Published in Journal of clinical oncology (20-07-2012)“…We evaluated the feasibility of administering carboplatin as a radiosensitizer during craniospinal radiation therapy (CSRT) to patients with high-risk…”
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Pilot Study of Intensive Chemotherapy With Peripheral Hematopoietic Cell Support for Children Less Than 3 Years of Age With Malignant Brain Tumors, the CCG-99703 Phase I/II Study. A Report From the Children's Oncology Group
Published in Pediatric neurology (01-07-2015)“…Abstract Background The primary goals of the Children's Cancer Group 99703 study were to assess the feasibility and tolerability of—as well as the response…”
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Motexafin-Gadolinium and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Children's Oncology Group Phase 2 Study
Published in International journal of radiation oncology, biology, physics (2013)“…Purpose To evaluate the effects on 1-year event-free survival (EFS) and overall survival (OS) of combining motexafin and gadolinium (MGd), a potent…”
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The prognostic value of histological grading of posterior fossa ependymomas in children: a Children's Oncology Group study and a review of prognostic factors
Published in Modern pathology (01-02-2008)“…We performed a retrospective analysis of 96 pediatric posterior fossa ependymomas in order to determine the prognostic value of histological grade based on the…”
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Induction Chemotherapy and Conformal Radiation Therapy for Very Young Children With Nonmetastatic Medulloblastoma: Children's Oncology Group Study P9934
Published in Journal of clinical oncology (10-09-2012)“…P9934 was a prospective trial of systemic chemotherapy, second surgery, and conformal radiation therapy (CRT) limited to the posterior fossa and primary site…”
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IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group
Published in Child's nervous system (01-01-2011)“…Purpose Recent studies have demonstrated a high frequency of IDH mutations in adult “secondary” malignant gliomas arising from preexisting lower grade lesions,…”
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Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features
Published in Journal of clinical oncology (10-04-2011)“…Despite significant progress in the molecular understanding of medulloblastoma, stratification of risk in patients remains a challenge. Focus has shifted from…”
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Second Solid Malignancies Among Children, Adolescents, and Young Adults Diagnosed With Malignant Bone Tumors After 1976 : Follow-Up of a Children's Oncology Group Cohort
Published in Cancer (01-11-2008)“…The growing number of individuals surviving childhood cancer has increased the awareness of adverse long-term sequelae. One of the most worrisome complications…”
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Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood : results from the Children's Cancer Group 945 cohort
Published in Journal of neurosurgery (01-11-2006)“…In reporting on molecular studies involving malignant gliomas in adults, authors have noted that deletions of PTEN and amplification of EGFR are common and may…”
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Long-Term Follow-Up of Children Treated for High-Grade Gliomas: Children's Oncology Group L991 Final Study Report
Published in Journal of clinical oncology (20-03-2012)“…High-grade gliomas of the CNS are characterized by poor treatment response and prognosis for long-term survival. The Children's Oncology Group (COG) L991 study…”
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A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high‐grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: A children's oncology group study
Published in Cancer (01-12-2007)“…BACKGROUND. An open‐label Phase II study of tipifarnib was conducted to evaluate its safety and efficacy in children with recurrent or refractory…”
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One-step approximations for detecting regime changes in the state space model with application to the influenza data
Published in Computational statistics & data analysis (01-01-2008)“…Kim and Nelson [1999. State Space Models with Regime Switching. MIT Press, Cambridge, MA] and others extended the framework of state space models involving…”
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Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children’s Oncology Group
Published in Journal of neuro-oncology (01-09-2010)“…Aberrant activation of Akt is a common finding in adult malignant gliomas, resulting in most cases from mutations or deletions involving PTEN , which allows…”
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Histology Predicts a Favorable Outcome in Young Children With Desmoplastic Medulloblastoma: A Report From the Children's Oncology Group
Published in Cancer (15-07-2011)“…Contemporary therapy for medulloblastoma results in adverse neurocognitive effects on young children, particularly those under the age of 3. Stratification of…”
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Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: A report from the children's oncology group
Published in Pediatric blood & cancer (01-12-2010)“…Background Alkylating agents are commonly used in the treatment of childhood malignant gliomas. Overexpression of O6‐methylguanine‐DNA methyltransferase (MGMT)…”
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Etoposide, vincristine, and cyclosporin A with standard-dose radiation therapy in newly diagnosed diffuse intrinsic brainstem gliomas: A pediatric oncology group phase I study
Published in Pediatric Blood & Cancer (15-10-2005)“…Background Brainstem gliomas (BSGs) are resistant to all therapy. Based on their imaging characteristics, we postulated that inhibition of P‐glycoprotein…”
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