Search Results - "THWAITES, G."

High levels of antimicrobial resistance among escherichia coli isolates from livestock farms and synanthropic rats and shrews in the Mekong Delta of Vietnam by Nhung, N T, Cuong, N V, Campbell, J, Hoa, N T, Bryant, J E, Truc, V N T, Kiet, B T, Jombart, T, Trung, N V, Hien, V B, Thwaites, G, Baker, S, Carrique-Mas, J

“…In Mekong Delta farms (Vietnam), antimicrobials are extensively used, but limited data are available on levels of antimicrobial resistance (AMR) among…”
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Clinical standards for the diagnosis, treatment and prevention of TB infection by Migliori, G. B., Wu, S. J., Matteelli, A., Zenner, D., Goletti, D., Ahmedov, S., Al-Abri, S., Allen, D. M., Balcells, M. E., Garcia-Basteiro, A. L., Cambau, E., Chaisson, R. E., Chee, C. B. E., Dalcolmo, M. P., Denholm, J. T., Erkens, C., Esposito, S., Farnia, P., Friedland, J. S., Graham, S., Hamada, Y., Harries, A. D., Kay, A. W., Kritski, A., Manga, S., Marais, B. J., Menzies, D., Ng, D., Petrone, L., Rendon, A., Silva, D. R., Schaaf, H. S., Skrahina, A., Sotgiu, G., Thwaites, G., Tiberi, S., Tukvadze, N., Zellweger, J.-P., D´Ambrosio, L., Centis, R., Ong, C. W. M.

“…BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) decreases the risk of developing TB disease and its associated morbidity and mortality. The aim of these…”
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The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults by McGill, F, Heyderman, R.S, Michael, B.D, Defres, S, Beeching, N.J, Borrow, R, Glennie, L, Gaillemin, O, Wyncoll, D, Kaczmarski, E, Nadel, S, Thwaites, G, Cohen, J, Davies, N.W.S, Miller, A, Rhodes, A, Read, R, Solomon, T

“…Summary Bacterial meningitis and meningococcal sepsis are rare conditions with high case fatality rates. Early recognition and prompt treatment saves lives. In…”
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Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans by Ashton, P. M., Thanh, L. T., Trieu, P. H., Van Anh, D., Trinh, N. M., Beardsley, J., Kibengo, F., Chierakul, W., Dance, D. A. B., Rattanavong, S., Davong, V., Hung, L. Q., Chau, N. V. V., Tung, N. L. N., Chan, A. K., Thwaites, G. E., Lalloo, D. G., Anscombe, C., Nhat, L. T. H., Perfect, J., Dougan, G., Baker, S., Harris, S., Day, J. N.

“…Cryptococcus neoformans ( C. neoformans var. grubii ) is an environmentally acquired pathogen causing 181,000 HIV-associated deaths each year. We sequenced 699…”
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Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features by Thwaites, GE, Chau, TTH, Stepniewska, K, Phu, NH, Chuong, LV, Sinh, DX, White, NJ, Parry, CM, Farrar, JJ

“…The diagnosis of tuberculous meningitis is difficult. Discrimination of cases from those of bacterial meningitis by clinical features alone is often…”
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Appropriate use of the Xpert® MTB/RIF assay in suspected tuberculous meningitis by Boyles, T. H., Thwaites, G. E.

“…We disagree with the recommendation by the World Health Organization to use Xpert® MTB/RIF on cerebrospinal fluid for the initial diagnosis of tuberculous…”
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UNITE4TB: a new consortium for clinical drug and regimen development for TB by Boeree, M. J., Lange, C., Thwaites, G., Paton, N., de Vrueh, R., Barros, D., Hoelscher, M., on behalf of the UNITE4TB Consortium

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Value of lipocalin 2 as a potential biomarker for bacterial meningitis by Thanh, T.T., Casals-Pascual, C., Ny, N.T.H., Ngoc, N.M., Geskus, R., Nhu, L.N.T., Hong, N.T.T., Duc, D.T., Thu, D.D.A., Uyen, P.N., Ngoc, V.B., Chau, L.T.M., Quynh, V.X., Hanh, N.H.H., Thuong, N.T.T., Diem, L.T., Hanh, B.T.B., Hang, V.T.T., Oanh, P.K.N., Fischer, R., Phu, N.H., Nghia, H.D.T., Chau, N.V.V., Hoa, N.T., Kessler, B.M., Thwaites, G., Tan, L.V.

“…Central nervous system (CNS) infections are common causes of morbidity and mortality worldwide. We aimed to discover protein biomarkers that could rapidly and…”
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Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition by Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodríguez-Baño, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R., Paterson, D.L.

“…To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI). Prospective studies,…”
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A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis by Seshadri, C, Thuong, N T T, Mai, N T H, Bang, N D, Chau, T T H, Lewinsohn, D M, Thwaites, G E, Dunstan, S J, Hawn, T R

“…The MR1 antigen-presenting system is conserved among mammals and enables T cells to recognize small molecules produced by bacterial pathogens, including…”
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Gram-negative bacteraemia; a multi-centre prospective evaluation of empiric antibiotic therapy and outcome in English acute hospitals by Fitzpatrick, J.M., Biswas, J.S., Edgeworth, J.D., Islam, J., Jenkins, N., Judge, R., Lavery, A.J., Melzer, M., Morris-Jones, S., Nsutebu, E.F., Peters, J., Pillay, D.G., Pink, F., Price, J.R., Scarborough, M., Thwaites, G.E., Tilley, R., Walker, A.S., Llewelyn, M.J., Melzer, Mark, Pink, Frederick, Fitzpatrick, Jennifer, Jones, Gill, Llewelyn, Martin, Peters, Joanna, Biswas, Jason, Edgeworth, Jonathan, Guile, Lucy, Querol-Rubiera, Antonio, Hussain, Abid, Jenkins, Neil, Moran, Ed, Pillay, Devedas, Scarborough, Matthew, Rawlinson, Tom, Judge, Ryan, Tilley, Robert, Lavery, Anita, Morris-Jones, Stephen, Price, James, Nsutebu, Emmanuel

“…Increasing antibiotic resistance makes choosing antibiotics for suspected Gram-negative infection challenging. This study set out to identify key determinants…”
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HAND, FOOT AND MOUTH DISEASE IN SOUTHERN VIETNAM DURING 2015 – 2021 by Nhu, L.N.T., Nhan, L.N.T., Khanh, T.H., Ny, N.T.H., Van, H.M.T., Hong, N.T.T., Nguyet, L.A., Thanh, T.T., Anh, N.T., Hang, V.T.T., Qui, P.T., Ha, D.Q., Thwaites, G., Chau, N.V.V., Thwaites, L., van Doorn, H.R., Hung, N.T., Tan, L.V.

“…Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential. In Vietnam, there have been two major outbreaks occurring during…”
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Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial by Thwaites, CL, Yen, LM, Loan, HT, Thuy, TTD, Thwaites, GE, Stepniewska, K, Soni, N, White, NJ, Farrar, JJ

“…The most common cause of death in individuals with severe tetanus in the absence of mechanical ventilation is spasm-related respiratory failure, whereas in…”
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MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage by Thuong, N T T, Tram, T T B, Dinh, T D, Thai, P V K, Heemskerk, D, Bang, N D, Chau, T T H, Russell, D G, Thwaites, G E, Hawn, T R, Caws, M, Dunstan, S J

“…Macrophage receptor with collagenous structure (MARCO) has an important role in the phagocytosis of Mycobacterium tuberculosis ( M. tuberculosis ). We…”
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Is a randomized trial of a short course of aminoglycoside added to β-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified? by Ong, D.S.Y., van Werkhoven, C.H., Cremer, O.L., Thwaites, G.E., Bonten, M.J.M.

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High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam by TU, L. T. P., HOANG, N. V. M., CUONG, N. V., CAMPBELL, J., BRYANT, J. E., HOA, N. T., KIET, B. T., THOMPSON, C., DUY, D. T., PHAT, V. V., HIEN, V. B., THWAITES, G., BAKER, S., CARRIQUE-MAS, J. J.

“…We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341…”
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TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam by Graustein, A.D, Horne, D.J, Arentz, M, Bang, N.D, Chau, T.T.H, Thwaites, G.E, Caws, M, Thuong, N.T.T, Dunstan, S.J, Hawn, T.R

“…Summary Humans exposed to Mycobacterium tuberculosis (Mtb) show variation in susceptibility to infection and differences in tuberculosis (TB) disease outcome…”
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A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis by Thuong, N T T, Hawn, T R, Thwaites, G E, Chau, T T H, Lan, N T N, Quy, H T, Hieu, N T, Aderem, A, Hien, T T, Farrar, J J, Dunstan, S J

“…Tuberculous meningitis (TBM) results from the haematogenous dissemination of Mycobacterium tuberculosis from the lung to the brain. Dissemination is believed…”
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Coxsackievirus A16 in Viet Nam by Le Nguyen Truc, N., Nguyen, T.A., Nguyen Thi Thu, H., Le, N.T.N., Hoang Minh Tu, V., Tran Tan, T., Vu Thi Ty, H., Nguyen Thi Han, N., Lam Anh, N., Truong Huu, K., Ha, M.T., Nguyen vanVinh, C., van Doorn, H.R., Thwaites, G., Le van, T.

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Hand, foot and mouth disease in southern Vietnam during 2015–2018 by Nguyen Thi Han, N., Le Nguyen Thanh, N., Truong Huu, K., Nguyen Thi Thu, H., Hoang Minh Tu, V., Le Nguyen Truc, N., Lam Anh, N., Tran Tan, T., Vu Thi Ty, H., Thwaites, G., Nguyen van Vinh, C., Thwaites, L., Le van, T.

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