Search Results - "THURMOND, L. M"

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients by Fava, M, Johe, K, Ereshefsky, L, Gertsik, L G, English, B A, Bilello, J A, Thurmond, L M, Johnstone, J, Dickerson, B C, Makris, N, Hoeppner, B B, Flynn, M, Mischoulon, D, Kinrys, G, Freeman, M P

“…We wanted to examine tolerability and efficacy of NSI-189, a benzylpiperizine-aminiopyridine neurogenic compound for treating major depressive disorder (MDD)…”
Get full text

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients by Fava, M, Johe, K, Ereshefsky, L, Gertsik, L G, English, B A, Bilello, J A, Thurmond, L M, Johnstone, J, Dickerson, B C, Makris, N, Hoeppner, B B, Flynn, M, Mischoulon, D, Kinrys, G, Freeman, M P

Get full text

Subcutaneous administration of CAMPATH-1H: clinical and biological outcomes by Schnitzer, T J, Yocum, D E, Michalska, M, Balius, R, Snider, M E, Hays, A, Thurmond, L M, Johnston, J M

“…A 24 week study of subcutaneous (sq) dosing with titration of CAMPATH-1H (C1H) dose against the circulating CD4+ T cell count in patients with rheumatoid…”
Get more information

A kinetic enzyme immunoassay for the quantitation of antibodies to a humanized monoclonal antibody in human serum by Thurmond, L.M., Reese, M.J., Donaldson, R.J., Orban, B.S.

“…A kinetic enzyme immunoassay was developed and validated to quantitate human antibodies to the humanized monoclonal antibody CAMPATH 1 C1H is a trademark of…”
Get full text

Improved biodistribution, tumor targeting, and reduced immunogenicity in mice with a gamma 4 variant of Campath-1H by J T Hutchins, F C Kull, Jr, J Bynum, V C Knick, L M Thurmond, P Ray

“…Radiolabeled antibodies have shown promise for the treatment of lymphoma and for solid tumor targeting. Campath-1H is a humanized monoclonal antibody that…”
Get full text

Differential neutralizing activity of human antibodies in interferon antiviral and natural killer cell bioassays by Thurmond, L M, Reese, M J

“…The ability of interferon-alpha (IFN-alpha) to augment the cytotoxicity of human natural killer (NK) cells was used to probe the neutralization capacity of…”
Get more information

Immunosuppression following exposure to 7,12-dimethylbenz[a]anthracene (DMBA) in Ah-responsive and Ah-nonresponsive mice by Thurmond, L M, Lauer, L D, House, R V, Cook, J C, Dean, J H

“…Recent reports suggest that the immunotoxicity of certain polycyclic aromatic hydrocarbons is associated with the Ah locus in mice. To test whether…”
Get more information

Suppression of splenic lymphocyte function by 7,12-dimethylbenz[a]anthracene (DMBA) in vitro by Thurmond, L M, House, R V, Lauer, L D, Dean, J H

“…The effects of the immunosuppressive polycyclic aromatic hydrocarbon (PAH) 7,12-dimethylbenz[a]anthracene (DMBA) were studied directly by in vitro exposure of…”
Get more information

Blastomyces dermatitidis chemotactic factor: kinetics of production and biological characterization evaluated by a modified neutrophil chemotaxis assay by THURMOND, L. M, MITCHELL, T. G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Intracellular cytokines may model immunoregulation of abacavir hypersensitivity in HIV-infected subjects by King, Deborah, Tomkins, Sarah, Waters, Anele, Easterbrook, Philippa J., Thurmond, Linda M., Thorborn, Daren E., Raffi, Francois, Kemeny, D. Mike, Vyakarnam, Annapurna

“…The clinical treatment of patients with HIV and adverse drug events may be enhanced by an understanding of the underlying mechanisms. About 4% of patients with…”
Get full text

Functional and biochemical disposition of 7,12-dimethylbenz[a]anthracene in murine lymphoid cells by Thurmond, L M, Tucker, A N, Rickert, D E, Lauer, L D, Dean, J H

“…The metabolism of the polycyclic aromatic hydrocarbon (PAH) 7,12-dimethylbenz[a]anthracene (DMBA) was studied in murine lymphocytes. This carcinogen has…”
Get more information

Effect of short-term inhalation exposure to 1,3-butadiene on murine immune functions by Thurmond, L M, Lauer, L D, House, R V, Stillman, W S, Irons, R D, Steinhagen, W H, Dean, J H

“…Interest in 1,3-butadiene (BD) as a potential immunomodulator was prompted by reports of an increased incidence of neoplasia in humans exposed to BD during the…”
Get more information

Inhibitory Activity of Synthetic Peptide Antibiotics on Feline Immunodeficiency Virus Infectivity In Vitro by Ma, Jia, Kennedy-Stoskopf, Suzanne, Jaynes, Jesse M, Thurmond, Linda M, Tompkins, Wayne A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Adenocarcinoma cells exposed in vitro to Navelbine or Taxol increase Ep-CAM expression through a novel mechanism by THURMOND, Linda M, STIMMEL, Julie B, INGRAM, Adrienne C, RYAN, Christian H, MURRAY, Doris M, EBERWEIN, Derek J, WITHERSPOON, Sam M, KNICK, Vincent C

“…Ep-CAM antigen expression was shown to vary by phase across the cell cycle. Following pretreatment of various adenocarcinoma cells in culture with clinically…”
Get full text

Erratum: A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients by Fava, M, Johe, K, Ereshefsky, L, Gertsik, L G, English, B A, Bilello, J A, Thurmond, L M, Johnstone, J, Dickerson, B C, Makris, N, Hoeppner, B B, Flynn, M, Mischoulon, D, Kinrys, G, Freeman, M P

“…Correction to: Molecular Psychiatry advance online publication, 8 December 2015; doi:10.1038/mp.2015.178 Following publication of this paper, the authors…”
Get full text

Immunochemical characterization of human antibodies to lymphobiastoid interferon by THURMOND, L. M., REESE, M. J.

“…SUMMARY Antibodies produced in recurrent respiratory papillomatosis (RRP) patients treated with Iymphoblastoid interferon (1yIKN) may neutralize antiviral…”
Get full text

Synovial tissue response to treatment with Campath-1H by Ruderman, E M, Weinblatt, M E, Thurmond, L M, Pinkus, G S, Gravallese, E M

“…Therapeutic trials in rheumatoid arthritis with the monoclonal antibody Campath-1H have demonstrated recurrent clinical synovitis in some patients, despite…”
Get more information

Antibodies in patients with recurrent respiratory papillomatosis treated with lymphoblastoid interferon by Thurmond, L M, Brand, C M, Leventhal, B G, Finter, N B, Johnston, J M

“…Serum specimens from 53 evaluable patients enrolled in a clinical trial of lymphoblastoid interferon in recurrent respiratory papillomatosis were screened for…”
Get more information

Immunochemical characterization of human antibodies to lymphoblastoid interferon by Thurmond, L M, Reese, M J

“…Antibodies produced in recurrent respiratory papillomatosis (RRP) patients treated with lymphoblastoid interferon (lyIFN) may neutralize antiviral activity or…”
Get full text

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir by Hetherington, Seth, Hughes, Arlene R, Mosteller, Michael, Shortino, Denise, Baker, Katherine L, Spreen, William, Lai, Eric, Davies, Kirstie, Handley, Abigail, Dow, David J, Fling, Mary E, Stocum, Michael, Bowman, Clive, Thurmond, Linda M, Roses, Allen D

“…Hypersensitivity to abacavir affects about 4% of patients who receive the drug for HIV-1 infection. We did a retrospective, case-control study to identify…”
Get full text