Search Results - "THRIEMER, Kamala"
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Towards the elimination of Plasmodium vivax malaria: Implementing the radical cure
Published in PLoS medicine (23-04-2021)“…In this review for the Vivax malaria collection, Kamala Thriemer and colleagues explore efforts to eliminate P. vivax malaria…”
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Plasmodium vivax in the Era of the Shrinking P. falciparum Map
Published in Trends in parasitology (01-06-2020)“…Plasmodium vivax is an important cause of malaria, associated with a significant public health burden. Whilst enhanced malaria-control activities have…”
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Antibiotic prescribing in DR Congo: a knowledge, attitude and practice survey among medical doctors and students
Published in PloS one (18-02-2013)“…Antibiotic resistance (ABR) particularly hits resource poor countries, and is fuelled by irrational antibiotic (AB) prescribing. We surveyed knowledge,…”
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Field evaluation of a novel semi-quantitative point-of-care diagnostic for G6PD deficiency in Indonesia
Published in PloS one (30-04-2024)“…The WHO recommends routine testing of G6PD activity to guide radical cure in patients with Plasmodium vivax malaria. Females may have intermediate G6PD enzyme…”
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Field evaluation of quantitative point of care diagnostics to measure glucose-6-phosphate dehydrogenase activity
Published in PloS one (02-11-2018)“…Glucose-6-Phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy worldwide, no reliable bedside diagnostic tests to quantify G6PD activity…”
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Study protocol for development of an options assessment toolkit (OAT) for national malaria programs in Asia Pacific to determine best combinations of vivax radical cure for their given contexts
Published in PloS one (09-03-2023)“…Recent advances in G6PD deficiency screening and treatment are rapidly changing the landscape of radical cure of vivax malaria available for National Malaria…”
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Field assessment of the operating procedures of a semi-quantitative G6PD Biosensor to improve repeatability of routine testing
Published in PloS one (19-01-2024)“…In remote communities, diagnosis of G6PD deficiency is challenging. We assessed the impact of modified test procedures and delayed testing for the…”
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Sharing results with participants (and community) in malaria related research: Perspectives and experience from researchers
Published in PLOS global public health (05-09-2023)“…Results-sharing with participants or their communities after the completion of research is an essential element of ethical research. The main objective of this…”
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Opening the policy blackbox: unravelling the process for changing national diagnostic and treatment guidelines for vivax malaria in seven countries
Published in Malaria journal (30-10-2021)“…The changing global health landscape has highlighted the need for more proactive, efficient and transparent health policy-making. After more than 60 years of…”
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Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso
Published in PLoS neglected tropical diseases (01-10-2019)“…Salmonella Typhimurium and Enteritidis are major causes of bloodstream infection in children in sub-Saharan Africa. This study assessed evidence for their…”
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Glucose 6 Phosphate Dehydrogenase (G6PD) quantitation using biosensors at the point of first contact: a mixed method study in Cambodia
Published in Malaria journal (04-10-2022)“…Quantitative measurement of Glucose-6-Phosphate Dehydrogenase (G6PD) enzyme activity is critical to decide on appropriate treatment and provision of radical…”
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A novel generation of hemozoin based malaria diagnostics show promising performance
Published in EClinicalMedicine (01-05-2020)Get full text
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Methods for the field evaluation of quantitative G6PD diagnostics: a review
Published in Malaria journal (11-09-2017)“…Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency are at risk of severe haemolysis following the administration of 8-aminoquinoline…”
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Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case-control data from Bangladesh
Published in PLoS medicine (23-04-2021)“…Glucose-6-phosphate dehydrogenase (G6PD) activity is dependent upon G6PD genotype and age of the red blood cell (RBC) population, with younger RBCs having…”
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Implementing radical cure diagnostics for malaria: user perspectives on G6PD testing in Bangladesh
Published in Malaria journal (12-05-2021)“…The radical cure of Plasmodium vivax requires treatment with an 8-aminoquinoline drug, such as primaquine and tafenoquine, to eradicate liver hypnozoite…”
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The risk of adverse clinical outcomes following treatment of Plasmodium vivax malaria with and without primaquine in Papua, Indonesia
Published in PLoS neglected tropical diseases (01-11-2020)“…The widespread use of primaquine (PQ) radical cure for P. vivax, is constrained by concerns over its safety. We used routinely collected patient data to…”
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A systematic review and meta-analysis of the performance of two point of care typhoid fever tests, Tubex TF and Typhidot, in endemic countries
Published in PloS one (16-12-2013)“…In the absence of well-equipped laboratory infrastructure in many developing countries the accurate diagnosis of typhoid fever is challenging. Rapid diagnostic…”
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G6PD Deficiency and Antimalarial Efficacy for Uncomplicated Malaria in Bangladesh: A Prospective Observational Study
Published in PloS one (29-04-2016)“…The Bangladeshi national treatment guidelines for uncomplicated malaria follow WHO recommendations but without G6PD testing prior to primaquine administration…”
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Variation in Complexity of Infection and Transmission Stability between Neighbouring Populations of Plasmodium vivax in Southern Ethiopia
Published in PloS one (15-10-2015)“…P. vivax is an important public health burden in Ethiopia, accounting for almost half of all malaria cases. Owing to heterogeneous transmission across the…”
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Adherence to 14-day radical cure for Plasmodium vivax malaria in Papua, Indonesia: a mixed-methods study
Published in Malaria journal (20-05-2023)“…Reducing the risk of recurrent Plasmodium vivax malaria is critical for malaria control and elimination. Primaquine (PQ) is the only widely available drug…”
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