Search Results - "THORN, Lena M"

A1C Variability Predicts Incident Cardiovascular Events, Microalbuminuria, and Overt Diabetic Nephropathy in Patients With Type 1 Diabetes by WADEN, Johan, FORSBLOM, Carol, THORN, Lena M, GORDIN, Daniel, SARAHEIMO, Markku, GROOP, Per-Henrik

“…A1C Variability Predicts Incident Cardiovascular Events, Microalbuminuria, and Overt Diabetic Nephropathy in Patients With Type 1 Diabetes Johan Wadén 1 , 2 ,…”
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The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes by THOMAS, Merlin C, MORAN, John L, WADEN, Johan, THORN, Lena M, MÄKINEN, Ville-Petteri, ROSENGARD-BÄRLUND, Milla, SARAHEIMO, Markku, HIETALA, Kustaa, HEIKKILÄ, Outi, FORSBLOM, Carol

“…The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes Per-Henrik Groop 1 , 2 , Merlin C. Thomas 3 , John L. Moran…”
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Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Seppälä, Matias, Lukander, Heidi, Wadén, Johan, Eriksson, Marika I, Harjutsalo, Valma, Groop, Per-Henrik, Thorn, Lena M

“…Sedentary behavior, such as excessive sitting, increases risk of cardiovascular disease and premature mortality in the general population, but this has not…”
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Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes by Antikainen, Anni A., Haukka, Jani K., Kumar, Anmol, Syreeni, Anna, Hägg-Holmberg, Stefanie, Ylinen, Anni, Kilpeläinen, Elina, Kytölä, Anastasia, Palotie, Aarno, Putaala, Jukka, Thorn, Lena M., Harjutsalo, Valma, Groop, Per-Henrik, Sandholm, Niina

“…Individuals with type 1 diabetes (T1D) carry a markedly increased risk of stroke, with distinct clinical and neuroimaging characteristics as compared to those…”
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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter? by Mutter, Stefan, Parente, Erika B, Januszewski, Andrzej S, Simonsen, Johan R, Harjutsalo, Valma, Groop, Per-Henrik, Jenkins, Alicia J, Thorn, Lena M

“…Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate…”
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Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes by Eriksson, Marika I, Hietala, Kustaa, Summanen, Paula, Harjutsalo, Valma, Putaala, Jukka, Ylinen, Anni, Hägg-Holmberg, Stefanie, Groop, Per-Henrik, Thorn, Lena M

“…As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes…”
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Leisure-time physical activity and development and progression of diabetic nephropathy in type 1 diabetes: the FinnDiane Study by Wadén, Johan, Tikkanen, Heidi K., Forsblom, Carol, Harjutsalo, Valma, Thorn, Lena M., Saraheimo, Markku, Tolonen, Nina, Rosengård-Bärlund, Milla, Gordin, Daniel, Tikkanen, Heikki O., Groop, Per-Henrik

“…Aims/hypothesis The aim of this study was to assess how physical activity predicts the development and progression of diabetic nephropathy in patients with…”
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The role of blood pressure in risk of ischemic and hemorrhagic stroke in type 1 diabetes by Hägg-Holmberg, Stefanie, Dahlström, Emma H, Forsblom, Carol M, Harjutsalo, Valma, Liebkind, Ron, Putaala, Jukka, Tatlisumak, Turgut, Groop, Per-Henrik, Thorn, Lena M

“…Hypertension is one of the strongest risk factors for stroke in the general population, while systolic blood pressure has been shown to independently increase…”
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The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes by Østergaard, Jakob Appel, Jansson Sigfrids, Fanny, Forsblom, Carol, Dahlström, Emma H., Thorn, Lena M., Harjutsalo, Valma, Flyvbjerg, Allan, Thiel, Steffen, Hansen, Troels Krarup, Groop, Per-Henrik

“…H-ficolin recognizes patterns on microorganisms and stressed cells and can activate the lectin pathway of the complement system. We aimed to assess H-ficolin…”
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Atrophy of the optic chiasm is associated with microvascular diabetic complications in type 1 diabetes by Tarkkonen, Aleksi, Claesson, Tor-Björn, Eriksson, Marika I, Forsblom, Carol, Thorn, Lena M, Summanen, Paula, Groop, Per-Henrik, Putaala, Jukka, Gordin, Daniel, Martola, Juha

“…Diabetic neuropathy and diabetic eye disease are well known complications of type 1 diabetes. We hypothesized that chronic hyperglycemia also damages the optic…”
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Metabolic Syndrome as a Risk Factor for Cardiovascular Disease, Mortality, and Progression of Diabetic Nephropathy in Type 1 Diabetes by THORN, Lena M, FORSBLOM, Carol, WADEN, Johan, SARAHEIMO, Markku, TOLONEN, Nina, HIETALA, Kustaa, GROOP, Per-Henrik

“…Metabolic Syndrome as a Risk Factor for Cardiovascular Disease, Mortality, and Progression of Diabetic Nephropathy in Type 1 Diabetes Lena M. Thorn , MD 1 , 2…”
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Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes by Eriksson, Marika I, Summanen, Paula, Gordin, Daniel, Forsblom, Carol, Shams, Sara, Liebkind, Ron, Tatlisumak, Turgut, Putaala, Jukka, Groop, Per-Henrik, Martola, Juha, Thorn, Lena M

“…IntroductionCerebral small-vessel disease is common in neurologically asymptomatic individuals with type 1 diabetes. The retinal vasculature is thought to…”
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Increased incidence of neurodegenerative diseases in Finnish individuals with type 1 diabetes by Satuli-Autere, Susanna, Harjutsalo, Valma, Eriksson, Marika I, Hägg-Holmberg, Stefanie, Öhman, Hanna, Claesson, Tor-björn, Groop, Per-Henrik, Thorn, Lena M

“…IntroductionDiabetes is linked to neurodegenerative diseases (NDs), but data in type 1 diabetes are scarce. Our aim was to assess the standardized incidence…”
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Cerebral Small Vessel Disease Is Associated With Smaller Brain Volumes in Adults With Type 1 Diabetes by Claesson, Tor-Björn, Putaala, Jukka, Shams, Sara, Salli, Eero, Gordin, Daniel, Mutter, Stefan, Tatlisumak, Turgut, Groop, Per-Henrik, Martola, Juha, Thorn, Lena M

“…Type 1 diabetes has been linked to brain volume reductions as well as to cerebral small vessel disease (cSVD). This study concerns the relationship between…”
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Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease by Dwivedi, Om Prakash, Barreiro, Karina, Käräjämäki, Annemari, Valo, Erkka, Giri, Anil K., Prasad, Rashmi B., Roy, Rishi Das, Thorn, Lena M., Rannikko, Antti, Holthöfer, Harry, Gooding, Kim M., Sourbron, Steven, Delic, Denis, Gomez, Maria F., Groop, Per-Henrik, Tuomi, Tiinamaija, Forsblom, Carol, Groop, Leif, Puhka, Maija

“…Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived mRNAs with potential to serve as a liquid kidney biopsy. We assessed…”
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Metabolic Phenotypes, Vascular Complications, and Premature Deaths in a Population of 4,197 Patients With Type 1 Diabetes by Mäkinen, Ville-Petteri, Forsblom, Carol, Thorn, Lena M, Wadén, Johan, Gordin, Daniel, Heikkilä, Outi, Hietala, Kustaa, Kyllönen, Laura, Kytö, Janne, Rosengård-Bärlund, Milla, Saraheimo, Markku, Tolonen, Nina, Parkkonen, Maija, Kaski, Kimmo, Ala-Korpela, Mika, Groop, Per-Henrik

“…Metabolic Phenotypes, Vascular Complications, and Premature Deaths in a Population of 4,197 Patients With Type 1 Diabetes Ville-Petteri Mäkinen 1 2 3 , Carol…”
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Comparison of Manual Cross-Sectional Measurements and Automatic Volumetry of the Corpus Callosum, and Their Clinical Impact: A Study on Type 1 Diabetes and Healthy Controls by Claesson, Tor-Björn, Putaala, Jukka, Shams, Sara, Salli, Eero, Gordin, Daniel, Liebkind, Ron, Forsblom, Carol, Summanen, Paula A, Tatlisumak, Turgut, Groop, Per-Henrik, Martola, Juha, Thorn, Lena M

“…Degenerative change of the corpus callosum might serve as a clinically useful surrogate marker for net pathological cerebral impact of diabetes type 1. We…”
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Lessons learned from the FinnDiane Study: Epidemiology and metabolic risk factors for diabetic kidney disease in type 1 diabetes by Jansson Sigfrids, Fanny, Lithovius, Raija, Groop, Per-Henrik, Thorn, Lena M

“…Across its operational span of more than 25 years, the observational, nationwide, multicentre Finnish Diabetic Nephropathy (FinnDiane) Study has aimed to…”
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Physical Activity Reduces Risk of Premature Mortality in Patients With Type 1 Diabetes With and Without Kidney Disease by Tikkanen-Dolenc, Heidi, Wadén, Johan, Forsblom, Carol, Harjutsalo, Valma, Thorn, Lena M, Saraheimo, Markku, Elonen, Nina, Tikkanen, Heikki O, Groop, Per-Henrik

“…The aims of the study were to assess how baseline leisure-time physical activity (LTPA) and its exercise components intensity, duration, and frequency are…”
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Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease by Smidtslund, Patrik, Jansson Sigfrids, Fanny, Ylinen, Anni, Elonen, Nina, Harjutsalo, Valma, Groop, Per-Henrik, Thorn, Lena M

“…To study prognosis after a first-ever myocardial infarction (MI) in type 1 diabetes, as well as how different MI- and diabetes-related factors affect the…”
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