Search Results - "THORAT, Mangesh A"

Prevention and early detection of prostate cancer by Cuzick, Jack, Prof, Thorat, Mangesh A, MBBS, Andriole, Gerald, Prof, Brawley, Otis W, Prof, Brown, Powel H, Prof, Culig, Zoran, MD, Eeles, Rosalind A, Prof, Ford, Leslie G, MD, Hamdy, Freddie C, Prof, Holmberg, Lars, Prof, Ilic, Dragan, PhD, Key, Timothy J, Prof, Vecchia, Carlo La, Prof, Lilja, Hans, Prof, Marberger, Michael, Prof, Meyskens, Frank L, Prof, Minasian, Lori M, MD, Parker, Chris, MD, Parnes, Howard L, MD, Perner, Sven, Prof, Rittenhouse, Harry, PhD, Schalken, Jack, Prof, Schmid, Hans-Peter, Prof, Schmitz-Dräger, Bernd J, Prof, Schröder, Fritz H, Prof, Stenzl, Arnulf, Prof, Tombal, Bertrand, Prof, Wilt, Timothy J, Prof, Wolk, Alicja, Prof

“…Summary Prostate cancer is a common malignancy in men and the worldwide burden of this disease is rising. Lifestyle modifications such as smoking cessation,…”
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Prognostic and Predictive Value of HER2 Expression in Ductal Carcinoma In Situ: Results from the UK/ANZ DCIS Randomized Trial by Thorat, Mangesh A, Levey, Pauline M, Jones, J Louise, Pinder, Sarah E, Bundred, Nigel J, Fentiman, Ian S, Cuzick, Jack

“…HER2 is overexpressed more frequently in ductal carcinoma in situ (DCIS) than in invasive breast cancer but its prognostic significance and predictive role for…”
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Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings by Li, Haojia, Whitney, Jon, Bera, Kaustav, Gilmore, Hannah, Thorat, Mangesh A, Badve, Sunil, Madabhushi, Anant

“…Oncotype DX (ODx) is a 12-gene assay assessing the recurrence risk (high, intermediate, and low) of ductal carcinoma in situ (pre-invasive breast cancer),…”
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Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment by Resetkova, Erika, Reis-Filho, Jorge S, Jain, Rohit K, Mehta, Rutika, Thorat, Mangesh A, Nakshatri, Harikrishna, Badve, Sunil

“…The concept of cancer cells being hierarchically organized and arising from their own progenitor stem cells will have important implications on cancer therapy…”
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FOXA1 Expression in Breast Cancer—Correlation with Luminal Subtype A and Survival by BADVE, Sunil, TURBIN, Dmitry, THORAT, Mangesh A, MORIMIYA, Akira, NIELSEN, Torsten O, PEROU, Charles M, DUNN, Sandi, HUNTSMAN, David G, NAKSHATRI, Harikrishna

“…Purpose: FOXA1, a forkhead family transcription factor, is essential for optimum expression of ∼50% of estrogen receptor α (ERα):estrogen responsive genes…”
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Breast cancer prevention in high-risk women by Thorat, Mangesh A., Balasubramanian, Rajeshkumar

“…Women at high risk of developing breast cancer are a heterogeneous group of women including those with and without high-risk germline mutation/s. Prevention in…”
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Digital interventions to moderate physical inactivity and/or nutrition in young people: a Cancer Prevention Europe overview of systematic reviews by McDermott, Kevin T, Noake, Caro, Wolff, Robert, Bauld, Linda, Espina, Carolina, Foucaud, Jérôme, Steindorf, Karen, Thorat, Mangesh A, Weijenberg, Matty P, Schüz, Joachim, Kleijnen, Jos

“…Strategies to increase physical activity (PA) and improve nutrition would contribute to substantial health benefits in the population, including reducing the…”
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Digital interventions to moderate alcohol consumption in young people: a Cancer Prevention Europe overview of systematic reviews by McDermott, Kevin T, Noake, Caro, Wolff, Robert, Espina, Carolina, Foucaud, Jérôme, Steindorf, Karen, Schüz, Joachim, Thorat, Mangesh A, Weijenberg, Matty, Bauld, Linda, Kleijnen, Jos

“…Strategies to reduce alcohol consumption would contribute to substantial health benefits in the population, including reducing cancer risk. The increasing…”
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A nomogram for predicting axillary node pathologic complete response—A necessary component of the path toward true axillary de‐escalation but needs a clear definition of the research question and a robust study design by Garg, Nidhi, Thorat, Mangesh A.

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Multiclonality of ER expression in DCIS - Implications for clinical practice and future research by Thorat, Mangesh A

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Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores by Ademuyiwa, Foluso O, Thorat, Mangesh A, Jain, Rohit K, Nakshatri, Harikrishna, Badve, Sunil

“…The Oncotype DX assay is one of the molecular tests that provide predictive and prognostic information to breast cancer patients with estrogen receptor…”
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Letter to the Editor: Cost-Efficacy Analysis of Use of Frozen Section Histology for Margin Assessment During Breast Conservation Surgery in Breast Cancer Patients by Garg, Nidhi, Thorat, Mangesh A.

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Role of glucocorticoids in breast cancer by Vaidya, Jayant S, Baldassarre, Gustavo, Thorat, Mangesh A, Massarut, Samuele

“…Glucocorticoids play an essential role in embryonic development and tissue homeostasis and possess important anti-inflammatory and immunosuppressive…”
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Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer by Thorat, Mangesh A, Cuzick, Jack, Chan, Andrew T

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Prophylactic use of aspirin: systematic review of harms and approaches to mitigation in the general population by Thorat, Mangesh A., Cuzick, Jack

“…A careful assessment of benefits and harms is required to assess suitability of aspirin as a prophylactic public health measure. However, comprehensive…”
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Role of Aspirin in Cancer Prevention by Thorat, Mangesh A., Cuzick, Jack

“…Since its first synthesis in 1897, several medicinal roles and mechanisms of action of aspirin have become apparent; the latest among these being its role in…”
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Liquid biopsy for cancer diagnosis and screening - The promise and challenges by Thorat, Mangesh A

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Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review by Atakpa, Emma C, Thorat, Mangesh A, Cuzick, Jack, Brentnall, Adam R

“…Endocrine therapy is effective at preventing or treating breast cancer. Some forms of endocrine therapy have been shown to reduce mammographic density. Reduced…”
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Sentinel lymph node assessment in breast cancer patients receiving neo‐adjuvant chemotherapy: to biopsy before or after? by Thorat, Mangesh A.

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Preventing invasive breast cancer using endocrine therapy by Thorat, Mangesh A., Cuzick, Jack

“…Developments in breast cancer treatment have resulted in reduction in breast cancer mortality in the developed world. However incidence continues to rise and…”
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