Search Results - "THOMPSON, Alexander J"

Daclatasvir, sofosbuvir, and ribavirin for hepatitis C virus genotype 3 and advanced liver disease: A randomized phase III study (ALLY‐3+) by Leroy, Vincent, Angus, Peter, Bronowicki, Jean‐Pierre, Dore, Gregory J., Hezode, Christophe, Pianko, Stephen, Pol, Stanislas, Stuart, Katherine, Tse, Edmund, McPhee, Fiona, Bhore, Rafia, Jimenez‐Exposito, Maria Jesus, Thompson, Alexander J.

“…Patients with hepatitis C virus (HCV) genotype 3 infection, especially those with advanced liver disease, are a challenging population in urgent need of…”
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Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model by Dora Tang, T-Y., Rohaida Che Hak, C., Thompson, Alexander J., Kuimova, Marina K., Williams, D. S., Perriman, Adam W., Mann, Stephen

“…Mechanisms of prebiotic compartmentalization are central to providing insights into how protocellular systems emerged on the early Earth. Protocell models are…”
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Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers by Thompson, Alexander J.V., Nguyen, Tin, Iser, David, Ayres, Anna, Jackson, Kathy, Littlejohn, Margaret, Slavin, John, Bowden, Scott, Gane, Edward J., Abbott, William, Lau, George K.K., Lewin, Sharon R., Visvanathan, Kumar, Desmond, Paul V., Locarnini, Stephen A.

“…Although threshold levels for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) titers have recently been proposed to guide therapy for…”
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Measuring the Viscosity of the Escherichia coli Plasma Membrane Using Molecular Rotors by Mika, Jacek T., Thompson, Alexander J., Dent, Michael R., Brooks, Nicholas J., Michiels, Jan, Hofkens, Johan, Kuimova, Marina K.

“…The viscosity is a highly important parameter within the cell membrane, affecting the diffusion of small molecules and, hence, controlling the rates of…”
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Australian recommendations for the management of hepatitis C virus infection: a consensus statement by Thompson, Alexander JV

“…Summary Chronic hepatitis C virus (HCV) infection affects 230 000 Australians, who are at risk of progressive liver fibrosis leading to cirrhosis, liver…”
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Stopping nucleot(s)ide analogues in non‐cirrhotic HBeAg‐negative chronic hepatitis B patients: HBsAg loss at 96 weeks is associated with low baseline HBsAg levels by Hall, Samuel A. L., Burns, Gareth S., Anagnostou, Despina, Vogrin, Sara, Sundararajan, Vijaya, Ratnam, Dilip, Levy, Miriam T., Lubel, John S., Nicoll, Amanda J., Strasser, Simone I., Sievert, William, Desmond, Paul V., Ngu, Meng C., Angus, Peter, Sinclair, Marie, Meredith, Christopher, Matthews, Gail, Revill, Peter A., Jackson, Kathy, Littlejohn, Margaret, Bowden, D. Scott, Locarnini, Stephen A., Visvanathan, Kumar, Thompson, Alexander J.

“…Summary Background and Aims Current guidelines recommend long‐term nucleot(s)ide analogue (NA) therapy for patients with HBeAg‐negative chronic hepatitis B…”
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Australian recommendations for the management of hepatocellular carcinoma: a consensus statement by Lubel, John S, Roberts, Stuart K, Strasser, Simone I, Thompson, Alexander J, Philip, Jennifer, Goodwin, Mark, Clarke, Stephen, Crawford, Darrell HG, Levy, Miriam T, Shackel, Nick

“…Introduction Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths both globally and in Australia. Surveillance for HCC in at‐risk populations…”
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The Global Impact of Hepatitis B Vaccination on Hepatocellular Carcinoma by Flores, Joan Ericka, Thompson, Alexander J, Ryan, Marno, Howell, Jessica

“…Over 1.5 million preventable new hepatitis B infections continue to occur each year and there are an estimated 296 million people living with chronic hepatitis…”
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Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction by Thompson, Alexander J, Fellay, Jacques, Patel, Keyur, Tillmann, Hans L, Naggie, Susanna, Ge, Dongliang, Urban, Thomas J, Shianna, Kevin V, Muir, Andrew J, Fried, Michael W, Afdhal, Nezam H, Goldstein, David B, McHutchison, John G

“…Background & Aims In a genome-wide association study of patients being treated for chronic hepatitis C, 2 functional variants in ITPA that cause inosine…”
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Point-of-Care Tests for Hepatitis B: An Overview by Xiao, Yinzong, Thompson, Alexander J., Howell, Jessica

“…Despite the heavy disease burden posed by hepatitis B, around 90% of people living with hepatitis B are not diagnosed globally. Many of the affected…”
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The Importance of Prisons in Achieving Hepatitis C Elimination: Insights from the Australian Experience by Winter, Rebecca J, Holmes, Jacinta A, Papaluca, Timothy J, Thompson, Alexander J

“…Following the availability of highly effective direct-acting antivirals (DAAs) to treat hepatitis C infection, the uptake of treatment by people living with…”
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A problem of proportions: estimates of metabolic associated fatty liver disease and liver fibrosis in Australian adults in the nationwide 2012 AusDiab Study by Farrell, Ann M., Magliano, Dianna J., Shaw, Jonathan E., Thompson, Alexander J., Croagh, Catherine, Ryan, Marno C., Howell, Jessica

“…Metabolic Associated Fatty Liver Disease (MAFLD) is the most common cause of liver disease in Australia, but prevalence data are limited. We aimed to describe…”
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Pelvic floor behavioral treatment for fecal incontinence and constipation in quiescent inflammatory bowel disease by Khera, Angela J., Chase, Janet W., Stillman, Barry C., Salzberg, Michael, Thompson, Alexander J. V., Basnayake, Chamara, Wilson-O'Brien, Amy, Kamm, Michael A.

“…Refractory bowel symptoms in quiescent inflammatory bowel disease (IBD) are common but evidence for effective management is limited. We aimed to determine…”
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The Cascade of Care for an Australian Community-Based Hepatitis C Treatment Service by Wade, Amanda J, Macdonald, Diana M, Doyle, Joseph S, Gordon, Adam, Roberts, Stuart K, Thompson, Alexander J, Hellard, Margaret E

“…Hepatitis C treatment uptake in Australia is low. To increase access to hepatitis C virus treatment for people who inject drugs, we developed a…”
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Enhanced antiviral treatment efficacy and uptake in preventing the rising burden of hepatitis C-related liver disease and costs in Australia by Sievert, William, Razavi, Homie, Estes, Chris, Thompson, Alexander J, Zekry, Amany, Roberts, Stuart K, Dore, Gregory J

“…Background and Aim Chronic hepatitis C virus (HCV) infection is an important cause of advanced liver disease and liver‐related deaths in Australia. Our aim was…”
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Clinical outcomes amongst elderly patients with inflammatory bowel disease by Sivanathan, Vithoosharan, Basnayake, Chamara, Connell, William, Wright, Emily, Ding, John Nik, Niewadomski, Ola, Stanley, Annalise, Wilson‐O'Brien, Amy, Fry, Stephanie, Samyue, Tamie, Lust, Mark, Flanagan, Emma, Thompson, Alexander J. V., Kamm, Michael A.

“…Abstract Backgrounds and aims Inflammatory bowel disease (IBD) affects a growing cohort of elderly patients. Our aim was to compare the quality of care…”
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The case for a universal hepatitis C vaccine to achieve hepatitis C elimination by Scott, Nick, Wilson, David P, Thompson, Alexander J, Barnes, Eleanor, El-Sayed, Manal, Benzaken, Adele Schwartz, Drummer, Heidi E, Hellard, Margaret E

“…The introduction of highly effective direct-acting antiviral (DAA) therapy for hepatitis C has led to calls to eliminate it as a public health threat through…”
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Impact of an Automated Population-Level Cirrhosis Screening Program Using Common Pathology Tests on Rates of Cirrhosis Diagnosis and Linkage to Specialist Care (CAPRISE): Protocol for a Pilot Prospective Single-Arm Intervention Study by Flores, Joan Ericka, Trambas, Christina, Jovanovic, Natasha, Thompson, Alexander J, Howell, Jessica

“…People with compensated cirrhosis receive the greatest benefit from risk factor modification and prevention programs to reduce liver decompensation and improve…”
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Assessing the feasibility, acceptability and impacts of an education program on hepatitis B testing uptake among ethnic Chinese in Australia: results of a randomised controlled pilot study by Xiao, Yinzong, Wallace, Jack, Ahad, Marvad, van Gemert, Caroline, Thompson, Alexander J, Doyle, Joseph, Lam, Ho Yin, Chan, Kico, Bennett, Gabrielle, Adamson, Emily, Yussf, Nafisa, Tang, Aurora, Pedrana, Alisa, Stoove, Mark, Hellard, Margaret, Howell, Jessica

“…In Australia, Chinese migrants are among the populations most affected by hepatitis B virus (HBV) infection but often experience late diagnosis or access to…”
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Inosine Triphosphate Protects Against Ribavirin-Induced Adenosine Triphosphate Loss by Adenylosuccinate Synthase Function by Hitomi, Yuki, Cirulli, Elizabeth T, Fellay, Jacques, McHutchison, John G, Thompson, Alexander J, Gumbs, Curtis E, Shianna, Kevin V, Urban, Thomas J, Goldstein, David B

“…Background & Aims Genetic variation of inosine triphosphatase ( ITPA ) causing an accumulation of inosine triphosphate (ITP) has been shown to protect patients…”
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