Search Results - "THOMAS, Venetta"
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Age-Associated Defect in Human TLR-1/2 Function
Published in Journal of Immunology (15-01-2007)“…The effects of aging on human TLR function remain incompletely understood. We assessed TLR function and expression in peripheral blood monocytes from 159…”
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2
Anaplasma phagocytophilum specifically induces tyrosine phosphorylation of ROCK1 during infection
Published in Cellular microbiology (01-07-2007)“…Anaplasma phagocytophilum, an obligate intracellular pathogen that persists within polymorphonuclear leucocytes, is the second most common tick-borne agent in…”
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3
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
Published in Nature Medicine (01-08-2002)“…The Lyme disease vaccine is based on the outer-surface lipoprotein (OspA) of the pathogen Borrelia burgdorferi, and 95% of vaccine recipients develop…”
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4
A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector
Published in Cell host & microbe (12-07-2007)“…The tick Ixodes scapularis is an efficient vector for microbes, including the Lyme disease agent Borrelia burgdorferi. Ticks engorging on vertebrates induce…”
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Cutting Edge: CD4 Is the Receptor for the Tick Saliva Immunosuppressor, Salp15
Published in The Journal of immunology (1950) (15-11-2006)“…Salp15 is an Ixodes scapularis salivary protein that inhibits CD4+ T cell activation through the repression of TCR ligation-triggered calcium fluxes and IL-2…”
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Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
Published in Nature medicine (01-11-1998)“…T-20, a synthetic peptide corresponding to a region of the transmembrane subunit of the HIV-1 envelope protein, blocks cell fusion and viral entry at…”
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Anaplasma phagocytophilum Increases Cathepsin L Activity, Thereby Globally Influencing Neutrophil Function
Published in Infection and Immunity (01-11-2008)“…Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis, is an unusual obligate intracellular pathogen that persists in neutrophils. A…”
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Coinfection with Borrelia burgdorferi and the Agent of Human Granulocytic Ehrlichiosis Alters Murine Immune Responses, Pathogen Burden, and Severity of Lyme Arthritis
Published in Infection and Immunity (01-05-2001)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Urea-dependent Signal Transduction by the Virulence Regulator UreR
Published in The Journal of biological chemistry (04-10-2002)“…Identification of the environmental triggers involved in the expression of virulence genes is a fundamental objective in studies of bacterial pathogens. For…”
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Anaplasma phagocytophilum Modulates gp91phox Gene Expression through Altered Interferon Regulatory Factor 1 and PU.1 Levels and Binding of CCAAT Displacement Protein
Published in Infection and Immunity (01-01-2005)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of UreR binding sites in the Enterobacteriaceae plasmid‐encoded and Proteus mirabilis urease gene operons
Published in Molecular microbiology (01-03-1999)“…The closely related Proteus mirabilis and Enterobacteriaceae plasmid‐encoded urease genes are positively regulated by the AraC‐like transcriptional activator…”
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12
Salp15, an Ixodes scapularis Salivary Protein, Inhibits CD4 + T Cell Activation
Published in Immunity (Cambridge, Mass.) (01-06-2002)“…Tick saliva has pleiotropic properties that facilitate persistence of the arthropod upon the host. We now describe a feeding-inducible protein in Ixodes…”
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Abstract 4352: Radiotherapy-induced plasma cytokine changes and skin toxicity in breast cancer patients
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Breast cancer is the most common neoplasm and the second leading cause of cancer death in American women. Radiotherapy (RT) is an effective adjuvant…”
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Abstract A45: Inflammatory biomarker c-reactive protein in radiotherapy-induced skin toxicities of breast cancer patients
Published in Cancer research (Chicago, Ill.) (01-01-2013)“…Abstract Purpose: Post-surgery adjuvant radiotherapy (RT) significantly reduces recurrence and metastasis of breast cancer. However, many patients experience…”
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Abstract 2613: Racial/Ethnic specific polygenic models of breast cancer risk
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Breast cancer is the most frequently diagnosed cancer and the second leading cause of cancer death in American women. Earlier family linkage studies…”
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Abstract 4704: Racial/ethnic differences in double-strand-break repair signaling in breast cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract To evaluate whether deficient DNA repair contributes to elevated DNA damage and breast carcinogenesis, we used a newly developed flow-cytometry assay…”
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Abstract 3204: Association between oxidative damage and early adverse skin reactions following postoperative adjuvant radiotherapy in breast cancer patients
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Breast cancer is the most frequently diagnosed cancer and the second leading cause of cancer death in American women. Lumpectomy followed by…”
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Anaplasma phagocytophilum Modulates gp91[superscript phox] Gene Expression through Altered Interferon Regulatory Factor 1 and PU.1 Levels and Binding of CCAAT Displacement Protein
Published in Infection and immunity (2005)“…Infection of neutrophil precursors with Anaplasma phagocytophilum, the causative agent of human granulocytic ehrlichiosis, results in downregulation of the…”
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Infection with Anaplasma phagocytophilum Inhibits Proliferation and Differentiation of Myeloid Progenitors: New Insight into Infection-Related Pancytopenia
Published in Blood (16-11-2005)“…Human granulocytic anaplasmosis (HGA) is a potentially fatal tick-borne disease caused by the obligate intracellular bacterium Anaplasma phagocytophilum, which…”
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Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults: e0131106
Published in PloS one (01-06-2015)“…Height has an extremely polygenic pattern of inheritance. Genome-wide association studies (GWAS) have revealed hundreds of common variants that are associated…”
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