Search Results - "THOMAS, Maren"
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MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma
Published in Cancer research (Chicago, Ill.) (01-08-2011)“…MicroRNAs (miRNA) aberrantly expressed in tumors may offer novel therapeutic approaches to treatment. miR-145 is downregulated in various cancers including…”
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Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma
Published in Neoplasia (New York, N.Y.) (01-07-2013)“…Abstract PURPOSE: The provirus integration site for Moloney murine leukemia virus 1 (Pim-1) kinase is overexpressed in various tumors and has been linked to…”
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Child and Caregiver Beliefs of Importance of Physical Function and Quality of Life in Juvenile Idiopathic Arthritis: A Survey Study
Published in Pediatric physical therapy (01-01-2024)“…To evaluate patient-caregiver beliefs of relative importance across 4 domains while living with juvenile idiopathic arthritis (JIA). This was a…”
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Analysis of transcriptional regulation of the human miR-17-92 cluster; evidence for involvement of Pim-1
Published in International journal of molecular sciences (07-06-2013)“…The human polycistronic miRNA cluster miR-17-92 is frequently overexpressed in hematopoietic malignancies and cancers. Its transcription is in part controlled…”
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PEI-complexed LNA antiseeds as miRNA inhibitors
Published in RNA biology (01-08-2012)“…Antisense inhibition of oncogenic or other disease-related miRNAs and miRNA families in vivo may provide novel therapeutic strategies. However, this approach…”
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Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma
Published in Neoplasia (New York, N.Y.) (01-07-2013)“…Abstract PURPOSE: The provirus integration site for Moloney murine leukemia virus 1 (Pim-1) kinase is overexpressed in various tumors and has been linked to…”
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Renal sulfate secretion is carbonic anhydrase dependent in a marine teleost, Pleuronectes americanus
Published in The American journal of physiology (01-02-1999)“…Though chemical assays indicate that carbonic anhydrase (CA) activity is present in marine teleost nephrons, CA inhibitors have no effect on urine pH or…”
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Synthesis and physiochemical properties of sulfamate derivatives as topical antiglaucoma agents
Published in Journal of medicinal chemistry (01-12-1992)Get full text
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Abstract 2187: RNAi- and U1 small nuclear interference (U1i)-mediated gene knockdown reveals the functional relevance of Pim-1 kinase in colon carcinoma and glioblastoma
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Pim-1 is a constitutively active serine/threonine kinase overexpressed in various tumors. Its role as proto-oncogene is based on several Pim-1 target…”
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Renal and cerebrospinal fluid formation pharmacology of a high molecular weight carbonic anhydrase inhibitor
Published in The Journal of pharmacology and experimental therapeutics (01-01-1997)“…To achieve selective inhibition of cytosolic and membrane-bound carbonic anhydrase (CA II and CA IV, respectively), we synthesized a polymer of molecular…”
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Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma12
Published in Neoplasia (New York, N.Y.) (01-07-2013)Get full text
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Abstract LB-482: MiRNA replacement therapy in vivo : antitumor effects of nanoparticle-formulated miR-145 and miR-33a, and targeting of Pim-1
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Various miRNAs are aberrantly expressed in cancer. In colon carcinoma, decreased levels of the pro-apoptotic and anti-proliferative miRNA-145 are…”
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Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor
Published in Journal of ocular pharmacology and therapeutics (01-02-1997)“…Dorzolamide is a powerful inhibitor of carbonic anhydrase (CA) II that penetrates the sclera and cornea to reach the ciliary process and lowers formation of…”
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Carbonic anhydrase
Published in The New England journal of medicine (18-07-1985)Get more information
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Synthesis and physicochemical properties of thiadiazolo[3,2-a]pyrimidinesulfonamides and thiadiazolo[3,2-a]triazinesulfonamides as candidates for topically effective carbonic anhydrase inhibitors
Published in Journal of medicinal chemistry (01-11-1987)“…A series of bicyclic 1,3,4-thiadiazolo[3,2-a]pyrimidine- and 1,3,4-thiadiazolo[3,2-a]triazine-7-sulfonamides were synthesized from…”
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Chemistry of the renal reabsorption of bicarbonate
Published in Canadian journal of physiology and pharmacology (01-12-1974)Get more information
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Acute mountain sickness
Published in The New England journal of medicine (01-06-1989)Get more information
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Preparation of a Filaricide. p-[bis-(Carboxy-methylmercapto)-arsino]-benzamide1
Published in Journal of the American Chemical Society (01-09-1946)Get full text
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Inhibition of Dihydropteroate Synthetase from Escherichia coli by Sulfones and Sulfonamides
Published in Antimicrobial Agents and Chemotherapy (01-06-1973)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The dissociation between renal HCO3- reabsorption and H+ secretion in the skate, Raja erinacea
Published in Pflügers Archiv (01-01-1974)Get full text
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