Search Results - "THOMAS, M. D"

Why are there race/ethnic differences in adult body mass index–adiposity relationships? A quantitative critical review by Heymsfield, S. B, Peterson, C. M, Thomas, D. M, Heo, M, Schuna, J. M., Jr

“…Body mass index (BMI) is now the most widely used measure of adiposity on a global scale. Nevertheless, intense discussion centers on the appropriateness of…”
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Mechanisms and Impacts of a Partial AMOC Recovery Under Enhanced Freshwater Forcing by Thomas, M. D., Fedorov, A. V.

“…The Atlantic Meridional Overturning Circulation (AMOC) is expected to weaken in the 21st century due to increased surface buoyancy. Such AMOC changes in ocean…”
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Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy by Sheard, Thomas M D, Shakespeare, Tayla B, Seehra, Rajpinder S, Spencer, Michael E, Suen, Kin M, Jayasinghe, Izzy

“…Amine-reactive esters of aromatic fluorescent dyes are emerging as imaging probes for nondescript staining of cellular and tissue architectures. We…”
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Integration of full divertor detachment with improved core confinement for tokamak fusion plasmas by Wang, L., Wang, H. Q., Ding, S., Garofalo, A. M., Gong, X. Z., Eldon, D., Guo, H. Y., Leonard, A. W., Hyatt, A. W., Qian, J. P., Weisberg, D. B., McClenaghan, J., Fenstermacher, M. E., Lasnier, C. J., Watkins, J. G., Shafer, M. W., Xu, G. S., Huang, J., Ren, Q. L., Buttery, R. J., Humphreys, D. A., Thomas, D. M., Zhang, B., Liu, J. B.

“…Divertor detachment offers a promising solution to the challenge of plasma-wall interactions for steady-state operation of fusion reactors. Here, we…”
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Why do individuals not lose more weight from an exercise intervention at a defined dose? An energy balance analysis by Thomas, D. M, Bouchard, C, Church, T, Slentz, C, Kraus, W. E, Redman, L. M, Martin, C. K, Silva, A. M, Vossen, M, Westerterp, K, Heymsfield, S. B

“…Weight loss resulting from an exercise intervention tends to be lower than predicted. Modest weight loss can arise from an increase in energy intake,…”
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Estimating the risk of crime and victimisation in people with intellectual disability: a data-linkage study by Nixon, Margaret, Thomas, Stuart D. M., Daffern, Michael, Ogloff, James R. P.

“…Purpose People with intellectual disability (PWID) appear more likely to be victims and perpetrators of crime. However, extant evidence pertaining to these…”
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The risks, needs and stages of recovery of a complete forensic patient cohort in an Australian state by Adams, Jonathon, Thomas, Stuart D M, Mackinnon, Tobias, Eggleton, Damien

“…Routine outcome measures are increasingly being mandated across mental health services in Australia and overseas. This requirement includes forensic mental…”
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Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy by Sheard, Thomas M. D, Hurley, Miriam E, Colyer, John, White, Ed, Norman, Ruth, Pervolaraki, Eleftheria, Narayanasamy, Kaarjel K, Hou, Yufeng, Kirton, Hannah M, Yang, Zhaokang, Hunter, Liam, Shim, Jung-uk, Clowsley, Alexander H, Smith, Andrew J, Baddeley, David, Soeller, Christian, Colman, Michael A, Jayasinghe, Izzy

“…Nanodomains are intracellular foci which transduce signals between major cellular compartments. One of the most ubiquitous signal transducers, the ryanodine…”
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Human energy expenditure: advances in organ‐tissue prediction models by Heymsfield, S. B., Peterson, C. M., Bourgeois, B., Thomas, D. M., Gallagher, D., Strauss, B., Müller, M. J., Bosy‐Westphal, A.

“…Summary Humans expend energy at rest (REE), and this major energy exchange component is now usually estimated using statistical equations that include weight…”
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First Evidence of Local E×B Drift in the Divertor Influencing the Structure and Stability of Confined Plasma near the Edge of Fusion Devices by Wang, H Q, Guo, H Y, Xu, G S, Leonard, A W, Wu, X Q, Groth, M, Jaervinen, A E, Watkins, J G, Osborne, T H, Thomas, D M, Eldon, D, Stangeby, P C, Turco, F, Xu, J C, Wang, L, Wang, Y F, Liu, J B

“…The structure of the edge plasma in a magnetic confinement system has a strong impact on the overall plasma performance. We uncover for the first time a…”
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Can a weight loss of one pound a week be achieved with a 3500-kcal deficit? Commentary on a commonly accepted rule by Thomas, D M, Martin, C K, Lettieri, S, Bredlau, C, Kaiser, K, Church, T, Bouchard, C, Heymsfield, S B

“…Despite theoretical evidence that the model commonly referred to as the 3500-kcal rule grossly overestimates actual weight loss, widespread application of the…”
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Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease by Hurley, Miriam E, White, Ed, Sheard, Thomas M D, Steele, Derek, Jayasinghe, Izzy

“…Rapid release of calcium from internal stores via ryanodine receptors (RyRs) is one of the fastest types of cytoplasmic second messenger signalling in…”
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SPH simulations of negative (nodal) superhumps: a parametric study by Wood, M. A., Thomas, D. M., Simpson, J. C.

“…Negative superhumps in cataclysmic variable systems result when the accretion disc is tilted with respect to the orbital plane. The line of nodes of the tilted…”
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Super-Resolution Analysis of the Origins of the Elementary Events of ER Calcium Release in Dorsal Root Ganglion Neurons by Hurley, Miriam E, Shah, Shihab S, Sheard, Thomas M D, Kirton, Hannah M, Steele, Derek S, Gamper, Nikita, Jayasinghe, Izzy

“…Coordinated events of calcium (Ca ) released from the endoplasmic reticulum (ER) are key second messengers in excitable cells. In pain-sensing dorsal root…”
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Anti-seizure effects of JNJ-54175446 in the intra-amygdala kainic acid model of drug-resistant temporal lobe epilepsy in mice by Mamad, Omar, Heiland, Mona, Lindner, Andreas U, Hill, Thomas D M, Ronroy, Ronan M, Rentrup, Kilian, Sanz-Rodriguez, Amaya, Langa, Elena, Heller, Janosch P, Moreno, Oscar, Llop, Jordi, Bhattacharya, Anindya, Palmer, James A, Ceusters, Marc, Engel, Tobias, Henshall, David C

“…There remains a need for new drug targets for treatment-resistant temporal lobe epilepsy. The ATP-gated P2X7 receptor coordinates neuroinflammatory responses…”
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Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy by Brindley, Elizabeth, Heiland, Mona, Mooney, Catherine, Diviney, Mairead, Mamad, Omar, Hill, Thomas D M, Yan, Yan, Venø, Morten T, Reschke, Cristina R, Batool, Aasia, Langa, Elena, Sanz-Rodriguez, Amaya, Heller, Janosch P, Morris, Gareth, Conboy, Karen, Kjems, Jørgen, Brennan, Gary P, Henshall, David C

“…The diagnosis of epilepsy is complex and challenging and would benefit from the availability of molecular biomarkers, ideally measurable in a biofluid such as…”
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Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus by Batool, Aasia, Hill, Thomas D M, Nguyen, Ngoc T, Langa, Elena, Diviney, Mairéad, Mooney, Catherine, Brennan, Gary P, Connolly, Niamh M C, Sanz-Rodriguez, Amaya, Cavanagh, Brenton L, Henshall, David C

“…Repetitive or prolonged seizures (status epilepticus) can damage neurons within the hippocampus, trigger gliosis, and generate an enduring state of…”
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Eddy-induced variability of the meridional overturning circulation in a model of the North Atlantic by Thomas, M. D., Zhai, X.

“…Observations of the Atlantic Meridional Overturning Circulation (AMOC) show that it varies on all timescales. Here we isolate the contribution of eddies to…”
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Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counselling for hereditary cancer: a systematic review by Willis, A.M., Smith, S.K., Meiser, B., Ballinger, M.L., Thomas, D.M., Young, M.‐A.

“…Evidence suggests that a significant proportion of individuals referred to cancer genetic counselling (GC) do not attend, and thus may not be engaged in…”
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A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma by Lewin, J, Khamly, K K, Young, R J, Mitchell, C, Hicks, R J, Toner, G C, Ngan, S Y K, Chander, S, Powell, G J, Herschtal, A, Te Marvelde, L, Desai, J, Choong, P F M, Stacker, S A, Achen, M G, Ferris, N, Fox, S, Slavin, J, Thomas, D M

“…Background: Preoperative radiotherapy (RT) is commonly used to treat localised soft-tissue sarcomas (STS). Hypoxia is an important determinant of…”
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