Search Results - "THOMALE, Ulrich Wilhelm"
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Loss of efficacy of subsequent nonsurgical therapy after primary treatment failure in pediatric low‐grade glioma patients—Report from the German SIOP‐LGG 2004 cohort
Published in International journal of cancer (15-12-2020)“…First‐line treatment of pediatric low‐grade glioma using surgery, radio‐ or chemotherapy fails in a relevant proportion of patients. We analyzed efficacy of…”
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Neurosurgical morbidity in pediatric supratentorial midline low‐grade glioma: Results from the German LGG studies
Published in International journal of cancer (15-10-2023)“…Surgical resection is a mainstay of treatment for pediatric low‐grade glioma (LGG) within all current therapy algorithms, yet associated morbidity is scarcely…”
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Favorable prognosis in pediatric brainstem low‐grade glioma: Report from the German SIOP‐LGG 2004 cohort
Published in International journal of cancer (15-06-2020)“…Reports on pediatric low‐grade glioma (LGG) of the caudal brainstem are retrospective with heterogeneous cohorts, variable treatments and inconsistent outcome…”
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Biopsies of Caudal Brainstem Tumors in Pediatric Patients—A Single-Center Retrospective Case Series
Published in World neurosurgery (01-09-2023)“…The indication for performing biopsies in patients with diffuse lesions in the brain stem is controversial. The possible risks associated with the technically…”
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Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO‐grade II—Report from the German/Swiss SIOP‐LGG 2004 cohort
Published in International journal of cancer (15-10-2020)“…Reports on pediatric low‐grade diffuse glioma WHO‐grade II (DG2) suggest an impaired survival rate, but lack conclusive results for genetically defined…”
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Tumor load rather than contrast enhancement is associated with the visual function of children and adolescents with optic pathway glioma – a retrospective Magnetic Resonance Imaging study
Published in Journal of neuro-oncology (01-02-2022)“…Introduction Optic pathway gliomas are often asymptomatic tumors occurring in children with neurofibromatosis type 1 (NF1 + OPG) or sporadically (spOPG)…”
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Secondary tethered cord syndrome in adult patients: retethering rates, long-term clinical outcome, and the effect of intraoperative neuromonitoring
Published in Acta neurochirurgica (01-09-2020)“…Background The strategy for surgical treatment of tethered cord syndrome in pediatric patients is well established but still bares challenges for adult…”
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Motor and functional outcome of selective dorsal rhizotomy in children with spastic diplegia at 12 and 24 months of follow-up
Published in Acta neurochirurgica (01-10-2021)“…Background Selective dorsal rhizotomy (SDR) in ambulatory children affected by cerebral palsy (CP) is a surgical treatment option to lower spasticity and…”
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TROPHY registry study design: a prospective, international multicenter study for the surgical treatment of posthemorrhagic hydrocephalus in neonates
Published in Child's nervous system (01-04-2019)“…Introduction Among children with hydrocephalus, neonates with intraventricular hemorrhage (IVH) and posthemorrhagic hydrocephalus (PH) are considered a group…”
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Epilepsy surgery in early infancy: A retrospective, multicenter study
Published in Epilepsia open (01-09-2023)“…Although epilepsy surgery is the only curative therapeutic approach for lesional drug‐resistant epilepsy (DRE), there is reluctance to operate on infants due…”
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Molecular characterisation of sporadic endolymphatic sac tumours and comparison to von Hippel–Lindau disease‐related tumours
Published in Neuropathology and applied neurobiology (01-10-2021)“…Aims Although inactivation of the von Hippel–Lindau gene (VHL) on chromosome 3p25 is considered to be the major cause of hereditary endolymphatic sac tumours…”
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The importance of routine genetic testing in pediatric epilepsy surgery
Published in Epilepsia open (01-04-2024)“…Genetic variants in relevant genes coexisting with MRI lesions in children with drug‐resistant epilepsy (DRE) can negatively influence epilepsy surgery…”
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Endoscopic Treatment of Isolated Fourth Ventricle: Clinical and Radiological Outcome
Published in Neurosurgery (01-04-2012)“…Treatment of an isolated fourth ventricle should be considered when clinical symptoms or a significant mass effect occur. To report clinical and radiographic…”
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Endoscopic and Microsurgical Treatment of Sylvian Fissure Arachnoid Cysts—Clinical and Radiological Outcome
Published in World neurosurgery (01-08-2015)“…Objective A Sylvian fissure arachnoid cyst (SAC) is a well-recognized location for an intracranial arachnoid cyst in the pediatric population. For those cysts,…”
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MGMT Promoter Methylation and BRAF V600E Mutations Are Helpful Markers to Discriminate Pleomorphic Xanthoastrocytoma from Giant Cell Glioblastoma
Published in PloS one (02-06-2016)“…Giant Cell Glioblastoma (gcGBM) and Pleomorphic Xanthoastrocytoma (PXA) are rare astroglial tumors of the central nervous system. Although they share certain…”
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Case Report: Hemispherotomy in the First Days of Life to Treat Drug-Resistant Lesional Epilepsy
Published in Frontiers in neurology (24-12-2021)“…Neonatal drug-resistant epilepsy is often caused by perinatal epileptogenic insults such as stroke, ischemia, hemorrhage, and/or genetic defects. Rapid seizure…”
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Adaption of neurosurgical resection patterns for pediatric low‐grade glioma spanning two decades—Report from the German LGG‐studies 1996–2018
Published in Cancer medicine (Malden, MA) (01-06-2024)“…Introduction Neurosurgery is considered the mainstay of treatment for pediatric low‐grade glioma (LGG); the extent of resection determines subsequent…”
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