Search Results - "THIRION, Sylvie"

Primary culture and phenotyping of murine chondrocytes by Berenbaum, Francis, Gosset, Marjolaine, Thirion, Sylvie, Jacques, Claire

“…The culture of chondrocytes is one of the most powerful tools for exploring the intracellular and molecular features of chondrocyte differentiation and…”
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Prostaglandins and sickness behavior: Old story, new insights by Pecchi, Emilie, Dallaporta, Michel, Jean, André, Thirion, Sylvie, Troadec, Jean-Denis

“…Abstract Previous evidence has shown that prostaglandins play a key role in the development of sickness behavior observed during inflammatory states. In…”
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The food-contaminant deoxynivalenol modifies eating by targeting anorexigenic neurocircuitry by Girardet, Clémence, Bonnet, Marion S, Jdir, Rajae, Sadoud, Medhi, Thirion, Sylvie, Tardivel, Catherine, Roux, Julien, Lebrun, Bruno, Wanaverbecq, Nicolas, Mounien, Lourdes, Trouslard, Jérôme, Jean, André, Dallaporta, Michel, Troadec, Jean-Denis

“…Physiological regulations of energy balance and body weight imply highly adaptive mechanisms which match caloric intake to caloric expenditure. In the central…”
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Central Inflammation and Sickness-Like Behavior Induced by the Food Contaminant Deoxynivalenol: A PGE2-Independent Mechanism by Girardet, Clémence, Bonnet, Marion S., Jdir, Rajae, Sadoud, Medhi, Thirion, Sylvie, Tardivel, Catherine, Roux, Julien, Lebrun, Bruno, Mounien, Lourdes, Trouslard, Jérôme, Jean, André, Dallaporta, Michel, Troadec, Jean-Denis

“…Deoxynivalenol (DON), one of the most abundant trichothecenes found on cereals, has been implicated in mycotoxicoses in both humans and farm animals. Low-dose…”
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Ghrelin Receptor (GHS-R1a) and Its Constitutive Activity in Somatotroph Adenomas: A New Co-targeting Therapy Using GHS-R1a Inverse Agonists and Somatostatin Analogs by Mear, Yves, Blanchard, Marie-Pierre, Defilles, Céline, Brue, Thierry, Figarella-Branger, Dominique, Graillon, Thomas, Manavela, Marcos, Barlier, Anne, Enjalbert, Alain, Thirion, Sylvie

“…Context: The ghrelin receptor GHS-R1a is highly expressed in human somatotroph adenomas and exhibits unusually high basal signaling activity. In humans, the…”
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Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene by Gosset, Marjolaine, Berenbaum, Francis, Levy, Arlette, Pigenet, Audrey, Thirion, Sylvie, Saffar, Jean-Louis, Jacques, Claire

“…Knee osteoarthritis (OA) results, at least in part, from overloading and inflammation leading to cartilage degradation. Prostaglandin E2 (PGE2) is one of the…”
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Inactivation of PITX2 Transcription Factor Induced Apoptosis of Gonadotroph Tumoral Cells by Acunzo, Julie, Roche, Catherine, Defilles, Celine, Thirion, Sylvie, Quentien, Marie-Helene, Figarella-Branger, Dominique, Graillon, Thomas, Dufour, Henry, Brue, Thierry, Pellegrini, Isabelle, Enjalbert, Alain, Barlier, Anne

“…Nonfunctioning pituitary adenomas (NFPA; gonadotroph derived), even not inducing hormonal hypersecretion, cause significant morbidity by compression…”
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Mechanical stress and prostaglandin E2 synthesis in cartilage by Gosset, Marjolaine, Berenbaum, Francis, Levy, Arlette, Pigenet, Audrey, Thirion, Sylvie, Cavadias, Simeon, Jacques, Claire

“…Knee osteoarthritis (OA) results, at least in part, from overloading and inflammation leading to cartilage degradation. Prostaglandin E2 (PGE2) is one of the…”
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Involvement of the Pituitary-Specific Transcription Factor Pit-1 in Somatolactotrope Cell Growth and Death: An Approach Using Dominant-Negative Pit-1 Mutants by Pellegrini, Isabelle, Roche, Cathy, Quentien, Marie-Helene, Ferrand, Mireille, Gunz, Ginette, Thirion, Sylvie, Bagnis, Claude, Enjalbert, Alain, Franc, Jean-Louis

“…The anterior pituitary-specific transcription factor Pit-1 was initially identified and cloned as a transactivator of the prolactin (PRL) and GH genes and…”
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RhoA inhibition is a key step in pituicyte stellation induced by A1-type adenosine receptor activation by Rosso, Lia, Peteri-Brunbäck, Brigitta, Vouret-Craviari, Valérie, Deroanne, Christophe, Troadec, Jean-Denis, Thirion, Sylvie, Van Obberghen-Schilling, Ellen, Mienville, Jean-Marc

“…Pituicyte stellation in vitro represents a useful model with which to study morphological changes that occur in vivo in these cells during times of high…”
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Concomitant Recruitment of ERK1/2 and p38 MAPK Signalling Pathway Is Required for Activation of Cytoplasmic Phospholipase A2via ATP in Articular Chondrocytes by Berenbaum, Francis, Humbert, Lydie, Bereziat, Gilbert, Thirion, Sylvie

“…Extracellular ATP is a pro-inflammatory mediator involved in the release of prostaglandin from articular chondrocytes, but little is known about its effects on…”
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GHS-R1a constitutive activity and its physiological relevance by Mear, Yves, Enjalbert, Alain, Thirion, Sylvie

“…Abundant evidences have shown that ghrelin, by its binding to GHS-R1a, plays an important role for fundamental physiological functions. Increasing attention is…”
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Culture and phenotyping of chondrocytes in primary culture by Thirion, Sylvie, Berenbaum, Francis

“…The culture of chondrocytes is one of the most powerful tool for exploring the intracellular and molecular features of chondrocyte differentiation and…”
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Concomitant recruitment of ERK1/2 and p38 MAPK signalling pathway is required for activation of cytoplasmic phospholipase A2 via ATP in articular chondrocytes by Berenbaum, Francis, Humbert, Lydie, Bereziat, Gilbert, Thirion, Sylvie

“…Extracellular ATP is a pro-inflammatory mediator involved in the release of prostaglandin from articular chondrocytes, but little is known about its effects on…”
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Up‐regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: Critical roles of the ERK‐1/2 and p38 signaling pathways by Masuko‐Hongo, Kayo, Berenbaum, Francis, Humbert, Lydie, Salvat, Colette, Goldring, Mary B., Thirion, Sylvie

“…Objective Microsomal prostaglandin E synthase 1 (mPGES‐1) is the final enzyme of the cascade that produces prostaglandin E2 (PGE2), a key actor in arthritis…”
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Ras and Rap1 govern spatiotemporal dynamic of activated ERK in pituitary living cells by Zeiller, Caroline, Blanchard, Marie-Pierre, Pertuit, Morgane, Thirion, Sylvie, Enjalbert, Alain, Barlier, Anne, Gerard, Corinne

“…The Ras/Raf/MEK/ERK is a conserved signalling pathway involved in the control of fundamental cellular processes. Despite extensive research, how this pathway…”
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ATP-evoked increases in [Ca2+]i and peptide release from rat isolated neurohypophysial terminals via a P2X2 purinoceptor by Troadec, Jean‐Denis, Thirion, Sylvie, Nicaise, Ghislain, Lemos, José R., Dayanithi, Govindan

“…The effect of externally applied ATP on cytosolic free Ca 2+ concentration ([Ca 2+ ] i ) was tested in single isolated rat neurohypophysial nerve terminals by…”
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Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas by ACUNZO, Julie, THIRION, Sylvie, BRUE, Thierry, ENJALBERT, Alain, BARLIER, Anne, ROCHE, Catherine, SAVEANU, Alexandru, GUNZ, Ginette, GERMANETTI, Anne Laure, COUDERC, Bettina, COHEN, Richard, FIGARELLA-BRANGER, Dominique, DUFOUR, Henry

“…In human somatotroph adenomas, growth hormone (GH) hypersecretion can be inhibited by somatostatin analogues such as octreotide. Unfortunately, serum GH levels…”
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Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations by Guéant-Rodriguez, Rosa-Maria, Guéant, Jean-Louis, Debard, Renée, Thirion, Sylvie, Hong, Lu Xiao, Bronowicki, Jean-Pierre, Namour, Farès, Chabi, Nicodème W, Sanni, Ambaliou, Anello, Guido, Bosco, Paolo, Romano, Corrado, Amouzou, Emile, Arrieta, Heidy R, Sánchez, Beatríz E, Romano, Antonino, Herbeth, Bernard, Guilland, Jean-Claude, Mutchinick, Osvaldo M

“…BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) 677C[rightwards arrow]T polymorphism is heterogeneously distributed worldwide, with the highest and…”
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Inactivation of transcription factor pit-1 to target tumoral somatolactotroph cells by Roche, Catherine, Rasolonjanahary, Ramahefarizo, Thirion, Sylvie, Goddard, Isabelle, Fusco, Alexandra, Figarella-Branger, Dominique, Dufour, Henry, Brue, Thierry, Franc, Jean-Louis, Enjalbert, Alain, Barlier, Anne

“…The treatment of growth hormone (GH)- and prolactin (PRL)-secreting tumors resistant to current therapeutic molecules (somatostatin and dopamine analogues)…”
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