Search Results - "THEN, Florian"
-
1
Association of obesity with disease outcome in multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-01-2023)“…BackgroundObesity reportedly increases the risk for developing multiple sclerosis (MS), but little is known about its association with disability…”
Get full text
Journal Article -
2
Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response
Published in Journal of neurology, neurosurgery and psychiatry (01-08-2017)“…ObjectiveTo analyse predictors for relapses and number of attacks under different immunotherapies in patients with neuromyelitis optica spectrum disorder…”
Get full text
Journal Article -
3
Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis
Published in Journal of neurology, neurosurgery and psychiatry (01-11-2018)“…ObjectiveHippocampal inflammation in anti-LGI1 encephalitis causes memory deficits, seizures and behavioural abnormalities. Recent findings suggest that…”
Get full text
Journal Article -
4
Mineralocorticoid Receptor Signaling in Peripheral Blood Cells in Patients with Multiple Sclerosis
Published in International journal of molecular sciences (15-08-2024)“…Multiple sclerosis (MS) is associated with alterations in neuroendocrine function, primarily the hypothalamic-pituitary-adrenal axis, including lower…”
Get full text
Journal Article -
5
Compromised tDCS-induced facilitation of motor consolidation in patients with multiple sclerosis
Published in Journal of neurology (01-10-2018)“…Objective To investigate whether consolidation after motor learning can be facilitated by offline (post-training) transcranial direct current stimulation…”
Get full text
Journal Article -
6
-
7
Clinical manifestations and immunomodulatory treatment experiences in psychiatric patients with suspected autoimmune encephalitis: a case series of 91 patients from Germany
Published in Molecular psychiatry (01-03-2022)“…Autoimmune encephalitis (AE) can rarely manifest as a predominantly psychiatric syndrome without overt neurological symptoms. This study’s aim was to…”
Get full text
Journal Article -
8
Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study
Published in EBioMedicine (01-06-2020)“…We aim to evaluate serum neurofilament light chain (sNfL), indicating neuroaxonal damage, as a biomarker at diagnosis in a large cohort of early multiple…”
Get full text
Journal Article -
9
Somatosensory evoked potentials and their relation to microstructural damage in patients with multiple sclerosis—A whole brain DTI study
Published in Frontiers in neurology (29-08-2022)“…Introduction Somatosensory evoked potentials (SSEP) play a pivotal role in the diagnosis and disease monitoring of multiple sclerosis (MS). Delayed latencies…”
Get full text
Journal Article -
10
Influence of female sex and fertile age on neuromyelitis optica spectrum disorders
Published in Multiple sclerosis (01-07-2017)“…Background: Gender and age at onset are important epidemiological factors influencing prevalence, clinical presentation, and treatment response in autoimmune…”
Get full text
Journal Article -
11
Diroximel fumarate in patients with relapsing–remitting multiple sclerosis: Final safety and efficacy results from the phase 3 EVOLVE-MS-1 study
Published in Multiple sclerosis (01-12-2023)“…Background: Diroximel fumarate (DRF) is approved for adults with relapsing–remitting multiple sclerosis (RRMS) in Europe and for relapsing forms of MS in the…”
Get full text
Journal Article -
12
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
Published in Cell (03-04-2009)“…Huntington's disease (HD) is an incurable neurodegenerative disease caused by neuronal accumulation of the mutant protein huntingtin. Improving clearance of…”
Get full text
Journal Article -
13
Outcome of MS relapses in the era of disease-modifying therapy
Published in BMC neurology (07-08-2017)“…In multiple sclerosis (MS), neurological disability results from incomplete remission of relapses and from relapse-independent progression. Intravenous high…”
Get full text
Journal Article -
14
Efficacy of fingolimod and interferon beta-1b on cognitive, MRI, and clinical outcomes in relapsing–remitting multiple sclerosis: an 18-month, open-label, rater-blinded, randomised, multicentre study (the GOLDEN study)
Published in Journal of neurology (01-12-2017)“…Cognitive impairment (CI) affects 40–65% of multiple sclerosis (MS) patients. This study attempted evaluating the effects of fingolimod and interferon beta-1b…”
Get full text
Journal Article -
15
Changes of central noradrenaline transporter availability in immunotherapy-naïve multiple sclerosis patients
Published in Scientific reports (04-09-2020)“…The neurotransmitter noradrenaline (NA) mediates arousal, attention and mood, and exerts anti-inflammatory and neuroprotective effects. Alterations of…”
Get full text
Journal Article -
16
Humoral COVID-19 vaccine response in patients with NMOSD/MOGAD during anti-IL-6 receptor therapy compared to other immunotherapies
Published in Multiple sclerosis (01-05-2023)“…Background: Data on the humoral vaccine response in patients on anti-interleukin-6 (IL-6) receptor therapy remain scarce. Objective: The main objective of our…”
Get full text
Journal Article -
17
Evaluation of Cognitive Deficits and Structural Hippocampal Damage in Encephalitis With Leucine-Rich, Glioma-Inactivated 1 Antibodies
Published in JAMA neurology (01-01-2017)“…Limbic encephalitis with leucine-rich, glioma-inactivated 1 (LGI1) antibodies is one of the most frequent variants of autoimmune encephalitis with antibodies…”
Get more information
Journal Article -
18
Glutamic acid decarboxylase antibody-associated neurological syndromes: Clinical and antibody characteristics and therapy response
Published in Journal of the neurological sciences (15-02-2023)“…Antibodies against glutamic acid decarboxylase (GAD-abs) at high serum levels are associated with diverse autoimmune neurological syndromes (AINS), including…”
Get full text
Journal Article -
19
Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study
Published in Journal of neurology (01-02-2017)“…Histamine H 3 receptor blockade may enhance lesion remyelination in multiple sclerosis (MS). The efficacy (using a magnetic resonance imaging marker of…”
Get full text
Journal Article -
20
Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS)
Published in Journal of neurology (01-02-2019)“…Background Cognitive impairment (CI) affects approximately one-third of the patients with early multiple sclerosis (MS) and clinically isolated syndrome (CIS)…”
Get full text
Journal Article