Search Results - "THARP, William G"

Coordinated regulation of gene expression and microRNA changes in adipose tissue and circulating extracellular vesicles in response to pioglitazone treatment in humans with type 2 diabetes by Nunez Lopez, Yury O., Casu, Anna, Kovacova, Zuzana, Petrilli, Alejandra M., Sideleva, Olga, Tharp, William G., Pratley, Richard E.

“…Pioglitazone, a PPARγ agonist, is used to treat type 2 diabetes (T2D). PPARγ is highly expressed in adipose tissue (AT), however the effects of pioglitazone to…”
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The neuroendocrine stress response compensates for suppression of insulin secretion by volatile anesthetic agents: An observational study by Tharp, William G., Breidenstein, Max W., Friend, Alexander F., Bender, S. Patrick, Raftery, Daniel

“…Alterations in perioperative metabolic function, particularly hyperglycemia, are associated with increased post‐operative complications, even in patients…”
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Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients by Irimia, Daniel, Liu, Su-Yang, Tharp, William G, Samadani, Azadeh, Toner, Mehmet, Poznansky, Mark C

“…Experimental systems that provide temporal and spatial control of chemical gradients are required for probing into the complex mechanisms of eukaryotic cell…”
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Sexually Dimorphic Diet-Induced Insulin Resistance in Obese Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)-Deficient Mice by Jaworski, Diane M, Sideleva, Olga, Stradecki, Holly M, Langlois, Garret D, Habibovic, Aida, Satish, Basanthi, Tharp, William G, Lausier, James, LaRock, Kyla, Jetton, Thomas L, Peshavaria, Mina, Pratley, Richard E

“…We report an MMP/TIMP-deficient mouse in which both sexes develop obesity when fed a standard chow diet. Circulating levels of matrix metalloproteinases (MMPs)…”
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Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo by Tharp, William G., Yadav, R., Irimia, D., Upadhyaya, A., Samadani, A., Hurtado, O., Liu, S‐Y., Munisamy, S., Brainard, D. M., Mahon, M. J., Nourshargh, S., Oudenaarden, A., Toner, M. G., Poznansky, Mark C.

“…We report for the first time that primary human neutrophils can undergo persistent, directionally biased movement away from a chemokine in vitro and in vivo,…”
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Regarding Anesthetics, Lung Function, and Models of Obesity by Tharp, William G.

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Obesity and Asthma: An Inflammatory Disease of Adipose Tissue Not the Airway by SIDELEVA, Olga, SURATT, Benjamin T, BLACK, Kendall E, THARP, William G, PRATLEY, Richard E, FORGIONE, Patrick, DIENZ, Oliver, IRVIN, Charles G, DIXON, Anne E

“…Obesity is a major risk factor for asthma; the reasons for this are poorly understood, although it is thought that inflammatory changes in adipose tissue in…”
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Adipose tissue natriuretic peptide receptor expression is related to insulin sensitivity in obesity and diabetes by Kovacova, Zuzana, Tharp, William G., Liu, Dianxin, Wei, Wan, Xie, Hui, Collins, Sheila, Pratley, Richard E.

“…Objective Cardiac natriuretic peptides (NPs) bind to two receptors (NPRA‐mediator of signaling; NPRC‐clearance receptor) whose ratio, NPRR (NPRA/NPRC),…”
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Origins of amyloid-β by Tharp, William G, Sarkar, Indra Neil

“…Amyloid-β plaques are a defining characteristic of Alzheimer Disease. However, Amyloid-β deposition is also found in other forms of dementia and in…”
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Intraoperative Considerations for Transgender Patients by Tsai, Mitchell H., Balla, Agnes, Tharp, William G.

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Body Habitus and Dynamic Surgical Conditions Independently Impair Pulmonary Mechanics during Robotic-assisted Laparoscopic Surgery: A Cross-sectional Study by Tharp, William G., Murphy, Serena, Breidenstein, Max W., Love, Collin, Booms, Alisha, Rafferty, Melissa N., Friend, Alexander F., Perrapato, Scott, Ahern, Thomas P., Dixon, Anne E., Bates, Jason H. T., Bender, S. Patrick

“…BACKGROUND:Body habitus, pneumoperitoneum, and Trendelenburg positioning may each independently impair lung mechanics during robotic laparoscopic surgery. This…”
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Effects of obesity, pneumoperitoneum, and body position on mechanical power of intraoperative ventilation: an observational study by Tharp, William G, Neilson, Maegan R, Breidenstein, Max W, Harned, Ryan G, Chatfield, Sydney E, Friend, Alexander F, Nunez, Denis, Abnet, Kevin R, Farhang, Borzoo, Klick, John C, Horn, Nathan, Bender, S Patrick, Bates, Jason H T, Dixon, Anne E

“…Mechanical power can describe the complex interaction between the respiratory system and the ventilator and may predict lung injury or pulmonary complications,…”
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Are You Down With TPP? Considering Transpulmonary Pressures as Opposed to Ventilator-Measured Pressures by Bender, S. Patrick, Tharp, William G.

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Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes by Tharp, William G, Gupta, Dhananjay, Sideleva, Olga, Deacon, Carolyn F, Holst, Jens J, Elahi, Dariush, Pratley, Richard E

“…Incretin hormone dysregulation contributes to reduced insulin secretion and hyperglycemia in patients with type 2 diabetes mellitus (T2DM). Resistance to…”
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Intraoperative Lung-Protective Ventilation Trends and Practice Patterns: A Report from the Multicenter Perioperative Outcomes Group by Bender, S. Patrick, Paganelli, William C., Gerety, Lyle P., Tharp, William G., Shanks, Amy M., Housey, Michelle, Blank, Randal S., Colquhoun, Douglas A., Fernandez-Bustamante, Ana, Jameson, Leslie C., Kheterpal, Sachin

“…BACKGROUND:The use of an intraoperative lung-protective ventilation strategy through tidal volume (TV) size reduction and positive end-expiratory pressure…”
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Effects of glucose and insulin on secretion of amyloid‐β by human adipose tissue cells by Tharp, William G., Gupta, Dhananjay, Smith, Joshua, Jones, Karen P., Jones, Amanda M., Pratley, Richard E.

“…Objective Obesity and type 2 diabetes mellitus are risk factors for developing Alzheimer disease. Overlapping patterns of metabolic dysfunction may be common…”
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Body Habitus and Dynamic Surgical Conditions Independently Impair Pulmonary Mechanics during Robotic-assisted Laparoscopic Surgery by Tharp, William G., Murphy, Serena, Breidenstein, Max W., Love, Collin, Booms, Alisha, Rafferty, Melissa N., Friend, Alexander F., Perrapato, Scott, Ahern, Thomas P., Dixon, Anne E., Bates, Jason H. T., Bender, S. Patrick

“…Background Body habitus, pneumoperitoneum, and Trendelenburg positioning may each independently impair lung mechanics during robotic laparoscopic surgery. This…”
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Thromboelastography Before Epidural Placement in a Thrombocytopenic Parturient With Gaucher Disease Treated With Imiglucerase: A Case Report by Tharp, William G, Farhang, Borzoo

“…Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia. Here we discuss assessment of…”
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Migration of Antigen-Specific T Cells Away from CXCR4-Binding Human Immunodeficiency Virus Type 1 gp120 by BRAINARD, Diana M, THARP, William G, POZNANSKY, Mark C, GRANADO, Elva, MILLER, Nicholas, TROCHA, Alicja K, REN, Xiang-Hui, CONRAD, Brian, TERWILLIGER, Ernest F, WYATT, Richard, WALKER, Bruce D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Treatment with the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin Improves Fasting Islet-Cell Function in Subjects with Type 2 Diabetes by D'Alessio, David A., Denney, Amanda M., Hermiller, Linda M., Prigeon, Ronald L., Martin, Julie M., Tharp, William G., Saylan, Monica Liqueros, He, YanLing, Dunning, Beth E., Foley, James E., Pratley, Richard E.

“…Context: Dipeptidyl peptidase 4 (DPP-4) inhibitors are proposed to lower blood glucose in type 2 diabetes mellitus (T2DM) by prolonging the activity of the…”
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