Search Results - "THAPAR, A"

Adolescent and adult differences in major depression symptom profiles by Rice, F., Riglin, L., Lomax, T., Souter, E., Potter, R., Smith, D.J., Thapar, A.K., Thapar, A.

“…•There are etiological and treatment differences between adult and adolescent depression.•We systematically compared adolescent and adult major depression…”
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Investigating the genetic underpinnings of early-life irritability by Riglin, L, Eyre, O, Cooper, M, Collishaw, S, Martin, J, Langley, K, Leibenluft, E, Stringaris, A, Thapar, A K, Maughan, B, O'Donovan, M C, Thapar, A

“…Severe irritability is one of the commonest reasons prompting referral to mental health services. It is frequently seen in neurodevelopmental disorders that…”
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Association between obesity and depressive disorder in adolescents at high risk for depression by Hammerton, G, Thapar, A, Thapar, A K

“…Objective: To examine the relationship between Body Mass Index (BMI) and depressive disorder in adolescents at high risk for depression. Design: Prospective…”
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The links between prenatal stress and offspring development and psychopathology: disentangling environmental and inherited influences by Rice, F, Harold, G T, Boivin, J, van den Bree, M, Hay, D F, Thapar, A

“…Exposure to prenatal stress is associated with later adverse health and adjustment outcomes. This is generally presumed to arise through early environmentally…”
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'The risks of playing it safe': a prospective longitudinal study of response to reward in the adolescent offspring of depressed parents by Rawal, A, Collishaw, S, Thapar, A, Rice, F

“…Alterations in reward processing may represent an early vulnerability factor for the development of depressive disorder. Depression in adults is associated…”
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Maternal and Paternal Smoking During Pregnancy and Risk of ADHD Symptoms in Offspring: Testing for Intrauterine Effects by LANGLEY, Kate, HERON, Jon, SMITH, George Davey, THAPAR, Anita

“…Maternal smoking during pregnancy is associated with attention deficit hyperactivity disorder (ADHD) in offspring. It is assumed by many that this association…”
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The impact of gestational stress and prenatal growth on emotional problems in offspring: a review by Rice, F., Jones, I., Thapar, A.

“…Objective:  Events occurring very early in life, even prenatally, may have long‐term effects on future health and behaviour. The influence of poor foetal…”
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Testosterone therapy for sexual dysfunction in men with Type 2 diabetes: a systematic review and meta‐analysis of randomized controlled trials by Algeffari, M., Jayasena, C. N., MacKeith, P., Thapar, A., Dhillo, W. S., Oliver, N.

“…Aim To evaluate the effectiveness of testosterone therapy on a range of sexual function domains in men with Type 2 diabetes. Method Electronic databases were…”
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Explaining risk for suicidal ideation in adolescent offspring of mothers with depression by Hammerton, G, Zammit, S, Thapar, A, Collishaw, S

“…It is well-established that offspring of depressed mothers are at increased risk for suicidal ideation. However, pathways involved in the transmission of risk…”
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The relative contribution of common and rare genetic variants to ADHD by Martin, J, O'Donovan, M C, Thapar, A, Langley, K, Williams, N

“…Attention deficit hyperactivity disorder (ADHD) is highly heritable. Genome-wide molecular studies show an increased burden of large, rare copy-number variants…”
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Sex‐specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population by Martin, Joanna, Taylor, Mark J., Rydell, Mina, Riglin, Lucy, Eyre, Olga, Lu, Yi, Lundström, Sebastian, Larsson, Henrik, Thapar, Anita, Lichtenstein, Paul

“…Background Attention deficit hyperactivity disorder (ADHD) is more commonly diagnosed in males than in females. A growing body of research suggests that…”
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Disentangling nature from nurture in examining the interplay between parent-child relationships, ADHD, and early academic attainment by Sellers, R, Harold, G T, Smith, A F, Neiderhiser, J M, Reiss, D, Shaw, D, Natsuaki, M N, Thapar, A, Leve, L D

“…Attention deficit hyperactivity disorder (ADHD) is highly heritable and is associated with lower educational attainment. ADHD is linked to family adversity,…”
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Familial transmission of depression and antisocial behavior symptoms: disentangling the contribution of inherited and environmental factors and testing the mediating role of parenting by Harold, G T, Rice, F, Hay, D F, Boivin, J, van den Bree, M, Thapar, A

“…Genetic and environmental influences on child psychopathology have been studied extensively through twin and adoption designs. We offer a novel methodology to…”
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Computerized cognitive training in attention-deficit/hyperactivity disorder (ADHD): a meta-analysis of randomized controlled trials with blinded and objective outcomes by Westwood, Samuel J., Parlatini, Valeria, Rubia, Katya, Cortese, Samuele, Sonuga-Barke, Edmund J. S.

“…This meta-analysis investigated the effects of computerized cognitive training (CCT) on clinical, neuropsychological and academic outcomes in individuals with…”
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Hypertension and the Post-carotid Endarterectomy Cerebral Hyperperfusion Syndrome by Bouri, S, Thapar, A, Shalhoub, J, Jayasooriya, G, Fernando, A, Franklin, I.J, Davies, A.H

“…Abstract Objective Cerebral hyperperfusion syndrome is a preventable cause of stroke after carotid endarterectomy (CEA). It manifests as headache, seizures,…”
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A risk calculator to predict adult attention-deficit/hyperactivity disorder: generation and external validation in three birth cohorts and one clinical sample by Caye, A, Agnew-Blais, J, Arseneault, L, Gonçalves, H, Kieling, C, Langley, K, Menezes, A M B, Moffitt, T E, Passos, I C, Rocha, T B, Sibley, M H, Swanson, J M, Thapar, A, Wehrmeister, F, Rohde, L A

“…Few personalised medicine investigations have been conducted for mental health. We aimed to generate and validate a risk tool that predicts adult…”
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Psychiatric gene discoveries shape evidence on ADHD’s biology by Thapar, A, Martin, J, Mick, E, Arias Vásquez, A, Langley, K, Scherer, S W, Schachar, R, Crosbie, J, Williams, N, Franke, B, Elia, J, Glessner, J, Hakonarson, H, Owen, M J, Faraone, S V, O'Donovan, M C, Holmans, P

“…A strong motivation for undertaking psychiatric gene discovery studies is to provide novel insights into unknown biology. Although attention-deficit…”
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Remote assessment of ADHD in children and adolescents: recommendations from the European ADHD Guidelines Group following the clinical experience during the COVID-19 pandemic by Santosh, P., Cortese, S., Hollis, C., Bölte, S., Daley, D., Coghill, D., Holtmann, M., Sonuga-Barke, E. J. S., Buitelaar, J., Banaschewski, T., Stringaris, A., Döpfner, M., Van der Oord, S., Carucci, S., Brandeis, D., Nagy, P., Ferrin, M., Baeyens, D., van den Hoofdakker, B. J., Purper-Ouakil, D., Ramos-Quiroga, A., Romanos, M., Soutullo, C. A., Thapar, A., Wong, I. C. K., Zuddas, A., Galera, C., Simonoff, E.

“…The COVID-19 pandemic led ADHD services to modify the clinical practice to reduce in-person contact as much as possible to minimise viral spread. This had…”
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Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies by THAPAR, A, LANGLEY, K, O'DONOVAN, M, OWEN, M

“…It is well established that attention deficit hyperactivity disorder (ADHD) is a familial and highly heritable disorder. Consequently, much effort is being…”
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Managing and preventing depression in adolescents by Thapar, Anita, Collishaw, Stephan, Potter, Robert, Thapar, Ajay K

“…Summary points Depression affects 1-6% of adolescents each year worldwide Diagnostic criteria for depression are the same as for adults, but the primary…”
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