Search Results - "THAMES, Howard D"

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    The Limitations of Model-Based Experimental Design and Parameter Estimation in Sloppy Systems by White, Andrew, Tolman, Malachi, Thames, Howard D, Withers, Hubert Rodney, Mason, Kathy A, Transtrum, Mark K

    Published in PLoS computational biology (01-12-2016)
    “…We explore the relationship among experimental design, parameter estimation, and systematic error in sloppy models. We show that the approximate nature of…”
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    Estimation of α/β for Late Rectal Toxicity Based on RTOG 94-06 by Tucker, Susan L., Ph.D, Thames, Howard D., Ph.D, Michalski, Jeff M., M.D, Bosch, Walter R., D.Sc, Mohan, Radhe, Ph.D, Winter, Kathryn, M.S, Cox, James D., M.D, Purdy, James A., Ph.D, Dong, Lei, Ph.D

    “…Purpose To estimate α/β, the parameter ratio from the linear-quadratic (LQ) model, for Grade ≥2 late rectal toxicity among patients treated on Radiation…”
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    Ultraviolet A does not induce melanomas in a Xiphophorus hybrid fish model by Mitchell, David L, Fernandez, André A, Nairn, Rodney S, Garcia, Rachel, Paniker, Lakshmi, Trono, David, Thames, Howard D, Gimenez-Conti, Irma

    “…We examined the wavelength dependence of ultraviolet (UV) ra-diation (UVR)-induced melanoma in a Xiphophorus backcross hybrid model previously reported to be…”
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    Computational Modeling of Micrometastatic Breast Cancer Radiation Dose Response by Smith, Daniel L., PhD, Debeb, Bisrat G., PhD, Thames, Howard D., PhD, Woodward, Wendy A., MD, PhD

    “…Purpose Prophylactic cranial irradiation (PCI) involves giving radiation to the entire brain with the goals of reducing the incidence of brain metastasis and…”
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    Mitigation and Treatment of Radiation-Induced Thoracic Injury With a Cyclooxygenase-2 Inhibitor, Celecoxib by Hunter, Nancy R., MS, Valdecanas, David, BS, Liao, Zhongxing, MD, Milas, Luka, MD, Thames, Howard D., PhD, Mason, Kathy A., MS

    “…Purpose To test whether a cyclooxygenase-2 inhibitor (celecoxib) could reduce mortality resulting from radiation-induced pneumonitis. Methods and Materials…”
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    Preclinical evaluation of molecular-targeted anticancer agents for radiotherapy by Krause, Mechthild, Zips, Daniel, Thames, Howard D., Kummermehr, Johann, Baumann, Michael

    Published in Radiotherapy and oncology (01-08-2006)
    “…The combination of molecular-targeted agents with irradiation is a highly promising avenue for cancer research and patient care. Molecular-targeted agents are…”
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    The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis by Wang, Aijin, Arantes, Stacey, Yan, Leqin, Kiguchi, Kaoru, McArthur, Mark J, Sahin, Aysegul, Thames, Howard D, Aldaz, C Marcelo, Macleod, Michael C

    Published in BMC cancer (22-09-2008)
    “…Overexpression of the bZip transcription factor, ATF3, in basal epithelial cells of transgenic mice under the control of the bovine cytokeratin-5 (CK5)…”
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    Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy by Tucker, Susan L, Dong, Lei, Cheung, Rex, Johnson, Jennifer, Mohan, Radhe, Huang, Eugene H, Liu, H Helen, Thames, Howard D, Kuban, Deborah

    “…To compare the fits of normal-tissue complication probability (NTCP) models based on rectal dose-wall histograms (DWHs) vs. dose-volume histograms (DVHs) when…”
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